J2D2
1.4K posts


@OMApproach If you worship him, you will try and follow his path. Jesus literally said I AM THE WAY!
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@Steve_Sailer No Les Miserables = Can't take this list that seriously
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@JohnDoyle It was a scary time.. My own wife was drinking bottles of wine a week and was constantly in a mood... Things are better now, thank God
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Gen X divorced Dads get a lot of flack on here, but the Moms are far more bleak. I can think of two examples recently of these women breaking up perfectly good families — inb4 “you never know,” well I do actually — because of some vague lockdown-induced sense of not being “fulfilled” or “appreciated.” I wonder how much of this was literally just spending too much time watching “shows” during Covid.
In one instance, one of these women left her husband and ended up following her 20-something daughter to Nashville. This woman is in her late 50s. What do you expect your Nashville experience to be?
Perhaps bleakest is that in many cases, they have horrible plastic surgery which makes them more “attractive” not because they’re more beautiful (or less aged) but because it signals greater availability to the guys they throw themselves at, who are quite often much younger.
I don’t care about age gaps and certainly am not naive enough to think that an older woman could ever “take advantage of” a young man, but it’s frankly pathetic that these women are unable to cope with the stage of life that they’re in.
Yes, we all know about the Gen X Dad having a “midlife crisis” (this trope is born from women being mad at a guy for enjoying his life — wow he’s driving a Corvette and dating a 25 year old he’s clearly in crisis) but less attention is paid to the female inability to cope with aging. They are literally in crisis!
It’s been popular for a while to mock women who delay falling into typical patterns of life — marriage, families, etc. — because they want to have their fun for as long as possible while not realizing that their window is closing. But since peak Woke I keep hearing stories of older women who DID fall into those patterns, and then just blew everything up because of some grass-is-greener fantasy probably induced or at least popularized by those younger women. NOT GOOD!
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I am slightly neurotic about being in my 50s -- I still have so much I want to do, and I want to stay in the best health I can. I also don't want my brain capacity to deteriorate.
So I ask you, dear X people, whether there's any scientific basis for what I'm doing for the ol' noggin.
My approach is this: keep my brain active in a bunch of different ways. So not just in my daily reading and writing, but also in learning a musical instrument, studying great chess games (I'm working my way through what Bobby Fischer called his 60 memorable games), and learning a foreign language.
Yes, of course a language has practical use, but just as important to me is that it gives my brain a different kind of workout from anything else I do.
I have no ironclad proof that this will lower my chances of Alzheimer's. But it makes sense. Opinions?
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@texasrunnerDFW @vtchakarova @tyillc AI coming for OF -- they really should focus on their substacks and be ready for the rainy days ahead
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Elon completely stole the banquet 😂
He was already posing for someone else when Xiaomi CEO Lei Jun walked up to his idol asking for a selfie
Elon instantly poses with the funniest face
does the same funny expression with Apple CEO Tim Cook too
Now Elon became the MAIN attraction across Chinese media and the entire world 🤣
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@Breaking911 Lol. He perp seems like he's in a decent mood right after
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🚨Transgender Schizophrenic Utahn Murdered Parents Because Mom Interfered With Genital Surgery🚨
Mia Bailey — born as Collin Troy Bailey (biological male) — shot both of his parents in the head.
Mia (Collin) said that he was scheduled to have his gender reassignment surgery, but claims that his mother put a stop to it.
In the coldest statement ever, Mia (Collin) said, “She (Mia’s mother) can’t say sorry to save her life, apparently.”
“I had one thing going on & she (Mia’s mother) took it away from me.”
“She was a target because she betrayed me.”
Mia (Collin) plead guilty to 2 counts of aggravated murder & aggravated assault
& was sentenced to 50 years in prison.
📍St. George, Utah
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@EricSpracklen I’m pretty sure maga boomers don’t want to get nuked
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This is not the same man I voted for. I honestly can’t even recognize him anymore.
An absolutely disgusting betrayal.
MAGA boomers please wake up, PRESIDENT TRUMP DOES NOT CARE ABOUT YOU.
Watcher.Guru@WatcherGuru
Reporter: "To what extent are Americans' financial situations motivating you to make a deal?" President Trump: "Not even a little bit…I don't think about Americans' financial situations."
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@TheAliceSmith lol- both Barbie and this. You felt contrarian saying both sucked, but that was the objective truth, IMHO
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@Biohazard3737 May the memory of your loved ones be eternal and God willing, you will see them again, over on the other shore. youtube.com/shorts/4Jjyd1p…

YouTube
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@VincentRK @UpToDate Does Open Evidence obviate Up to Date? What about other AI? I think for me it has.
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Here is the inside story on how @UpToDate does what it does.
From my experience as an author/section editor for UpToDate for 20 years, here is how it works. It’s amazing!
Every day a team of people @UpToDate scour the top medical journals (and major meeting abstracts) for articles of importance. In my case they pertain to myeloma and related disorders. Any article that is felt to be important is sent to a expert MD medical editor at UpToDate who reviews the paper. If the information is felt to be important, the relevant chapter is updated with this content, summarized in a few sentences in Word track and then sent to the author of the chapter who is a top expert in the field.
As an author I have to review the update in detail and then make a decision whether to include the new information, and whether the way it has been incorporated is correct or needs to be edited.
Once I make a decision, it is then reviewed by an expert section editor. For 15 years for me, the section editor was Dr. Robert Kyle! (Currently I’m the section editor and we have about 6 experts serve as authors on over 40 chapters pertaining to myeloma and related disorders). The section editor independently decides whether the author made the right call and either approves or we have a back and forth till we agree.
The updated chapter is then reviewed again by the expert MD editor at UpToDate and then posted.
For important phase III trials or FDA approvals we usually make the update within a week. Sometimes by the next day! With so many important papers, every week there are 2-3 updates pertaining to my chapters that go through the above process! It’s hard work but it keeps me ridiculously current. And more importantly it keeps the content accurate and current. This is not random addition of new information. It’s vetted information that’s added.
Every UpToDate chapter is also peer reviewed annually. Each chapter also undergoes an annual author and editor review to make sure that the overall content and flow is good and to delete content that may be no longer important or accurate. The extraordinary process and rigor involved is why it’s such an invaluable irreplaceable resource. It is AMAZING and hard to replicate.
UpToDate is easy to navigate. But the newly launched UpToDate Expert AI takes it to the next level! It makes the entire content available to query just like you query a top ranked LLM. But it’s not searching the random internet or a stack of published articles. It’s primarily trained and derives vetted and adjudicated UpToDate content. It will not randomly hallucinate. It will not list 10 options for treatment newly diagnosed myeloma but will give you what experts currently feel is the best option based on the latest evidence. All answers are referenced and pointing to specific content sections in UpToDate (which also has links to source material). So you can immediately get all the background information if you need more detail.
Working with UpToDate has helped my career immensely. For the last 20 years it has been impossible for me to not know about every important study related to myeloma and related disorders as they get published! For 20 years, I have received a precise summary of every important article published in my field. More importantly I am forced to read them, review the source material, and make a judgment call. As a result I remember this stuff. A gift indeed!
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@AJ_Route7 @FordDavid15084 @Serenitee_Sam No hospital will even engage in that kind of conversation with even a genuine parent. Of course, this is a skit to farm payout.
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POV: You thought the “Under 2” free flight rule was a suggestion.
Watching this airline supervisor stand her ground is oddly satisfying. If you can’t prove the age, you pay the fare. Period. The way she handled the "call the hospital" bluff? Professionalism at its peak.
Southwest really said: “Receipts or a seat."
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@texasrunnerDFW @unusual_whales Boomers are just holding the money for their children, many whom are millennials. A great wealth transfer is happening despite the occasional boomer who wants to blow their fortune on a good time in their 80s
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@unusual_whales What percentage did the Silent Generation hold when the boomers were 40?
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@Dmm1010472 @chriswithans They are copying a playbook from another group that have mastered milking the morons in govt
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@chriswithans He has 3 other wives- all claiming to be single moms with multiple children. They are collecting benefits and he’s pocketing and deciding how to spend. This is very common. Muslim guy lives in a compound in WA - over 10 wives (current/former) collecting benefits, 25 kids
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