KC Martin-Stone

@internetuserf12 56% of patients with ME/CFS in one study had brain sag on MRI. This is the cardinal sign for CSF leak, but is rarely (never) investigated. My hypothesis is that CSF-lymphatic fistula is the likely primary lesion in many cases of ME/CFS. Only recognised in 2024 as a type of leak.

We don’t yet know the primary lesion in ME/CFS. We do consistently observe multi-system dysfunction - mitochondrial, immune, autonomic, and metabolic. Until an upstream node is identified, most treatments target downstream effects - essentially a game of whack-a-mole. One emerging hypothesis is that antigen-presenting cell (APC) injury may represent a central regulatory node.

You don’t say…

the science is clear. there has never been any evidence for droplet transmission, when there’s a big amount for aerosols. it’s basic physics. plus, you can’t generate droplets without generating large amount of aerosols. it’s safe to assume all respiratory pathogens are airborne.

📣 Louder now, for the people up the back 📣

Here are 5 reasons why I would wear a respirator, if I lived somewhere with a Meningitis B outbreak.

@sxwrkr_ Cool, good luck!

@KCMartinStone Great news, my gf has one thank u!

Has anyone had heavy lollipop-head to where your most comfortable position is leaning on your elbows and then your hands start getting like … nerve damage And what can be done to fix it haha 👉🥹👈

Does anyone know when the AirFanta 4Lite will be back in stock? @Engineer_Wong ?

@sxwrkr_ I had CCI badly for 6 years. I tried 12 different pillows in the first year. Bought new furniture so I could rest my head. Saw doctors, physios, acupuncturists, etc. Nothing helped, until I figured out this balance program. The improvement for me was profound.

@sxwrkr_ Forgot to say - make sure the balance board is not on a slippery surface. If you have wooden / tiled / polished concrete / other hard floors, place it on a yoga mat or folded towel.

@niyana_holt @JaneCaro Forced adoptions didn’t stop when the single mother’s pension began. They continued until the 1980s, at least.

@JaneCaro Lots of families had a daughter leave town? Some didn’t tell their parents. Our family removed my sister for 6 mths, baby adopted. I heard that Margaret Whitlam, working at the hospital saw the dilemma and that’s when a single Mother’s pension began and adoptions stopped.

These were the supposed ‘good old days’ before feminism revealed the cruelty and disdain for women that underpinned all the bullshitty ‘family values’ patriarchy is so nostalgic for. Horrifying ugliness & judgemental brutality. smh.com.au/national/nsw/d…

It's ok to work from home to support war, but not to protect health.

This should be tattooed onto the palm of every "health correspondent": You're more likely to develop invasive meningococcal disease if you have low CD4 T cell counts. And you're more likely to have low CD4 T cell counts after a Covid infection.

Spinal CSF-venous fistulas almost always arise from meningeal diverticula. The diverticular size can vary from tiny (submillimeter) to massive (think dural ectasia). At least one-third of diverticula change size when a fistula forms ⁦@spinalCSFleak⁩ pubmed.ncbi.nlm.nih.gov/41730631/

@urbanmel Holy fuck, that’s negligent

Email from NDIS where they have declined my application, but have not assessed me on MY disabilities. They’ve assessed me on a number of disabilities that weren’t in my application and left out ones that were. Is this normal? 🤷🏼‍♀️

@AndrewCallenMD I include CVF surgery in that question, because CVFs caused by ⬆️ CSF pressure indicate localised dural weakness, too, even if the valve effect of the CVF prevents adjacent CSF loss prior to sealing. Anyway, these are my wandering thoughts this morning. Congrats on the paper!

@AndrewCallenMD I assume the erosion in the above tweet is a relatively severe example, but it points to the possibility of microscopic erosion in a potentially significant portion of cases. Could this support a suggestion for the standard use of fibrin pre closure in all / most leak surgery?

Sacral dural tears in #SIH are probably under-recognized. Why? Because the sacrum often isn’t scrutinized, or sometimes even included in the field of view on routine spine imaging. In a new multicenter @AJNR study we found: • Sacral leaks often produce isolated sacral CSF collections • Image-guided patching can lead to meaningful clinical & imaging improvement • Longitudinal imaging suggests some lesions mimicking “Tarlov cysts” may actually represent chronic or partially healed leaks Encouraging to see multicenter collaboration continue to emerge in SIH imaging/treatment research. ajnr.org/content/early/…