Kathryn Prame Kumar

Commencing in January 2022,we have a full-time funded (NHMRC) PhD project available. Focussed on the role of neutrophil extracellular traps in autoimmune vasculitis. Based at @SCSMonash @MonashCID, @Monash_FMNHS. Please retweet-details 👇 supervisorconnect.med.monash.edu/projects/defin…

New online! @KitchingLab and @MHickey_IVM describe how in vivo imaging has advanced our understanding of immune cell behaviour and dynamics in the kidney go.nature.com/2ZrmMJB @MonashCID @SCSMonash @MonashUni

The latest review on enteric neuron–immune interactions has just landed @MucosalImmunol! This is a must read–such an impt theme from both immunological and physiological perspectives rdcu.be/cw787 @_Ryan_Wang_ @BornsteinLab @FoongJaime @Nicola_L_Harris @MonashImmPath

Delighted to share my first (co)first author paper “#Microbiota from young mice counteracts selective age-associated behavioral deficits” out today @NatureAging. Thank you to everyone involved, especially co1st authors @BoehmeMarcus @Thomazsan 🧵1/ ... nature.com/articles/s4358…

Skeletal muscle cells in a zebrafish embryo photographed through a microscope. #CellBiology #microscopy #SciArt

Just posted a new preprint! We studied the enteric nervous system (ENS) - the neurons that sit in your gut and control digestion. We focused on an often-underappreciated feature of the ENS – its macro-scale organization, and how this differs between regions of the intestines. 1/5

1/Folks with mainly biology training sometimes ask me for resources that can help them learn bioinformatics. This short thread has my recommendations at various levels.

Congratulations to all presentation winners of @ImmuMon, especially Sarah Jones, Sarah Snelgrove and Brooke Wanrooy from @MonashCID @SCSMonash #ImmuMon

Intestinal barrier is often overlooked in the context of IBS symptoms. This new systematic review concludes there's a positive association between loss of barrier function and symptoms such as abdominal pain and changes in IBS ow.ly/BSiF30rzJ7T

Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health - Another great review from our @IrishResearch Postdoc @BerdingHarold - Great to have our Australian @foodmoodcentre collaborators involved too! academic.oup.com/advances/advan…

Increased intestinal permeability can contribute to the activation of the immune system and inflammation. These findings show, for the first time, that a polyphenol rich-diet can reduce serum zonulin levels, an indirect marker of intestinal permeability ow.ly/nhBQ30rz5b9

A neuronal growth cone photographed through a microscope. Actin filaments and microtubules are shown. #CellBiology #microscopy #SciArt

REVIEW | Disorders of the enteric nervous system — a holistic view go.nature.com/36AMITF This figure shows the extrinsic and intrinsic factors shaping ENS structure and function.

Paper published @FrontImmunol! Thanks to everyone who helped me throughout PhD, especially to @GutsyBiotech @cwonglab and @MHickey_IVM lab members!!! Shoutout to @KPrameKumar @sciencewithray Shu and Brooke for all the support, and lunches and bubble tea!!! frontiersin.org/articles/10.33…

@sjsijieshen @FrontImmunol @GutsyBiotech @cwonglab @MHickey_IVM @sciencewithray Congrats on your hard work Sj! Well deserved 👏👏🎉

Therapeutic approaches targeting the gut-brain axis may represent the next avenue for the treatment of psychiatric disorders. This new review in @FrontImmunol covers reciprocal interactions between gut microbes and the CNS during experimental disease ow.ly/uhST30rlpn6

[NEW POST] A recent study provides new insights into the transcriptomic landscape of the #ENS and its constituent cells by profiling 5,068 mouse and 1,445 human enteric neurons and diverse gut cell types at the single-cell level. ow.ly/8Kb750Cf5O4

A cancer cell sitting on a circle as seen through a microscope. If by "seen" I meant to say I made a single 3D color projection from three grayscale Z stacks, changed the hue in photoshop in -20 increments, and then made an animated gif in Fiji. Yeah, seen. #CellBiology #sciart

Fiber is a major tool for shaping the gut microbiome. This review from 2018 that shares @ProfWhelan offers a good overview on how dietary fiber impacts gut microbial ecology, host physiology, and health ow.ly/jh6k30rgmBE

New content online: The enteric nervous system: the hub in a star network dlvr.it/Rk48XK