Leuschner Lab retweetledi
Leuschner Lab
14 posts
Leuschner Lab
@LeuschnerLab
Heisenberg Professorship for Immunocardiology @Uniklinik_hd
Heidelberg, Deutschland Katılım Mayıs 2024
160 Takip Edilen81 Takipçiler
Leuschner Lab retweetledi
Using the first mouse model of tricuspid valve regurgitation, we identify a cardio-intestinal innate immune circuit in which chronic venous congestion reprograms monocytes into IL-6-producing drivers of heart failure.
doi.org/10.64898/2026.…
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Check out the latest issue of @CircRes with our Echo-Guided IR Method on the cover ♥️ 🥢
Circulation Research@CircRes
@CircRes May 9th Issue is Out! ahajrnls.org/3wPOBJJ Cover: Representative IF staining of endothelial cells (magenta), inflammation (yellow), & WGA (green) in a 4-chamber view of a heart 7 days after Echocardiography-Guided Induction of I/R;nuclei-blue.
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Leuschner Lab retweetledi
Leuschner Lab retweetledi
In @Circres we describe a novel Echocardiography-Guided Method for Induction of Myocardial Ischemia/Reperfusion.
Check out the full study here: doi.org/10.1161/CIRCRE…
Great collaborative effort with @leuschnerlab, @lavinelab, @jacksonlab @rkramann @dzhk_germany @ImmunoFibHF
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scRNA-Seq profiling of 🫀interstitial cells reveals fibrosis in HFpEF to be distinct from HFrEF including the induction of basement membrane collagens and a protective ⬆️ of ANGPTL4 in murine and human HFpEF | led by @LauraWienecke and @jan_lanzer
doi.org/10.1007/s00395…
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Leuschner Lab retweetledi
What do Angptl4 and collagen IV have to do with fibrosis in HFpEF?🫀 Proud to have found some answers!🔬 Thanks to my co-first @jan_lanzer, all authors and our supervisor team for excellent support @LeuschnerLab @JulioSaezRod 👌🏻 link.springer.com/article/10.100…
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Leuschner Lab retweetledi
Molecular fibroblast activation patterns in heart failure.
link.springer.com/article/10.100…
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Leuschner Lab retweetledi
Check out our paper just published in Circulation
➡️ Translation controls inflammation after myocardial infarction
doi.org/10.1161/CIRCUL…
This work was a huge collaborative effort over many years.
@dzhk_germany @DGK_org @VolkersMirko
Key findings + paper summary below 🧵⬇️⬇️⬇️
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Leuschner Lab retweetledi
Read my Tools of the Trade article, published in @NatRevCardiol, highlighting my experience with and the method of ultrasound guided induction of myocardial infarction:
rdcu.be/dLgU3
Thanks to @FloSicklinger & F. Leuschner for developing such an innovative method.
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Leuschner Lab retweetledi
Couldn't attend the #Immuno-#Cardiology Symposium @FondationLeducq @jacksonlab? No problem-> read the report 'Linking immune modulation to cardiac fibrosis' here 👉 rdcu.be/dIUBP
#fibrosis #cardioimmunology
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A shortcut to the infarcted heart
Excited to share our collaborative effort with @DenisSchapiro lab led by @FloSicklinger and @FloWuenne. Using spatial omics technologies, we found a new way how monocytes sneak into the infarcted heart.
biorxiv.org/content/10.110…
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Leuschner Lab retweetledi
I am very excited to share our lab's first preprint @uniklinik_hd together with the @LeuschnerLab. This study was led by @FloWuenne and @FloSicklinger. biorxiv.org/cgi/content/sh…
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