OptiNeuro BioSciences

I have found, and most other researchers find similar, is that it doesn’t really increase desire, but it does initiate the physical response of being VERY 🦏. Similar to the days of puberty when the wind blowing would set you off. For increasing desire, I stack with Kiss or oxytocin (as needed).

PT-141 is the peptide nobody wants to talk about publicly. But privately? DMs are flooded. It activates melanocortin receptors in the brain. Boosts desire at the signal level. Works through the central nervous system, not blood flow. Men over 30 need to know about this one. 🔥

@NomadHH @BowTiedUM It’s everywhere… especially nootropic focused suppliers.

@BowTiedUM Cant find Bromantane anywhere damn it

The "Limitless Pill" hook has been spammed so hard People now associate it with "Mid" Sucks for them because we figured out the real limitless stack as of Today Bromantane Sublingual NALT DLPA Vilon Circadian UVA/B in retina or Chroma Trinity (get UV/Red 20x+ faster than sun)

@ElevateBiohack @irvinnofficial I’ve also tried KW, which is potent stuff, but I couldn’t sleep for 24 hours. The M6 version is still debatable as to its effectiveness. I’ve got a batch, but I’m skeptical it works. I don’t get the same results as KW

@OptiNeuroBio @irvinnofficial I love it as well. I’m about a 50/50 blend as well.

It’s here

@Retardutide Yes, I noticed that when reading the article. Big red flag was when one of the Hospira and Ocean vials failed (for different reasons) and they followed up with “oops, our bad”.

Hospira: Overpriced, Overrated. Twas good while it lasted Hospira senpai. Genetek is gonna be the new go to bac water now for most people. Indian pharma grade. Cheap. Consistently tests well. ebay.io/m/xXhkmz You're welcome!

Been using Selank for many, many years (back when we had to import from Russian pharmacies, sometimes by way of Europe). Selank (or its stronger mods like NA-Selank Amidate or Adlank) is a good anti-anxiety pep. It’s very helpful for folks with strong ADHD and have trouble sleeping.

Opinions on Selank? I have some now thinking about adding to my bunny rabbit’s nighttime routine. 🙂

@Devloncowart @Dr_JonesDC This is the ideal stack of you’re having food noise issues on reta.

@Dr_JonesDC Whats your thoughts on Cagrilintide stacked with Reta?

Stacking Retatrutide and Tirzepatide isn't reckless. Maxing out either one is. Most people have this exactly backwards.

@KrisRChase For me, I push myself to give something at least 3 months of solid research, unless it’s giving me negative results.

real question for the group. how do you decide a peptide isn't working and you're done with it? a set number of weeks, a specific marker, or you just quietly lose interest and the vial dies in the fridge?

@ArcasDream @irvinnofficial Very similar to both, but a bit more potent (at least according to animal studies). Not as long lasting as armoda, but longer than moda.

@irvinnofficial please let us know how it compares to moda and armoda when you have a chance.

@BowTiedHRT Nice! Epitalon and pinealon are two highly underrated peptides in my opinion. From my 30+ years of nootropic research, I find pinealon a quite helpful addition to any good nootropic stack.

Elite Research Always ahead of the curve! New drops from Elite Research USA 🇺🇸 today: Epitalon+ capsules, Pinealon+ capsules, Cartalax lyophilized, and PE-22-28. The Epitalon and Pinealon caps are enteric coated, so they pass through the stomach intact and dissolve in the upper intestine. They are also formulated with sodium caprate to increase intestinal permeability and absorption. No one else is offering this AND we’ve reduced the price! PE-22-28 nasal spray is still rare in this space. If you have not looked into the compound, it is worth reading up on before deciding whether it belongs in your research bag. Cartalax works upstream on cartilage specific gene expression for structural rebuilding, a slower and more targeted process than the systemic, angiogenic repair we expect from BPC-157. And of course, Elite has the best price on Hospira Bac water you’ll find anywhere. Code 🪙🦊♌️ SFL10 🪙🦊♌️ eliteresearchusa.com/?code=SFL10

@BiohackerJake Wow… thank you for sharing. I always find it interesting to hear about other people’s experiences and stacks.

My current Biohacking protocol (July 2026). And more information about who I am behind the X mask. TRT + Hormones: -Testosterone Cypionate: EOD -Desiccated Thyroid (NP Thyroid): Daily AM fasted -HGH: Daily AM fasted Peptides & Research Compounds: -Retatrutide: Monday/Wednesday/Friday -Tesofensine: AM daily -Melanotan 1: Random as needed -MOTS-C: Daily-AM -BPC-157 + TB-500+ KPV: Daily AM -Follistatin FLRG-242: Wednesday AM -ATX 304: Daily AM -GW:0742: Daily AM -SR-9011: Daily AM -Tesamorelin: Sunday-Thursday night -SLU-PP-915: Daily AM Daily Medications / Supports: -LDN (Low Dose Naltrexone): -Tadalafil: Daily AM -Metformin + Dihydroberberine (split between lunch/dinner) -Telmisartan: Daily PM Core Daily Supplements: -Gorilla Mind Elite Multi-Vitamin -Ubiquinol -Omega 3 Fish Oil -Nattokinase+Citrus Bergamot -NAC -Vitamin D3/K2 -Taurine -Selenium -Creatine Monohydrate -Astragalus -Boron -Curcumin/Turmeric -Alpha-GPC -TMG -Glycine -Magnesium Glycinate and Threonate Nutrition & Intake: -Protein: 275–350g daily -Fiber: From food/berries+ psyllium husk -Water: 200+ oz daily + Celtic sea salt (AM + PM) -Caffeine: 450-550mg daily -Meals are breakfast, post-lift, lunch, dinner, and pre bed time (2 hours prior). -Current calorie intake between 3500-4500est. Training (Every Day): -Resistance Training: 40–45 min heavy dumbbells, rotating muscle groups, 8–10 sets of 10–12 reps -Incline Treadmill Walks (all at 10% incline, 2 mph): 30 min post-breakfast + 30 min post-lunch + 30 min post-dinner (90 min total daily) Recent removals: Cagrilintide Dihexa/Noopept/J-147 Planned additions in near future: -IGF 1-LR once Tesa experiment is done. -Potentially messing with Eloralintide -Likely increasing TRT weekly dosing again. -Anavar/Primo (likely Q3). Main goal: Continue my own research and path of raising BMR as high as possible, to be able to enjoy the lifestyle I would like, while able to fend off fat gain and still gain muscle, due to the combination of compounds we have available, that makes it the most possible its ever been during our time. --- What you get with me is an authentic person. Not going to hound you with questions on bloodwork. It’s purely my own journey and what has worked for me. I have spent countless hours this year with a ton of free time, to be able to come out of the woodworks with experience I can share that I have actually done myself. Not chasing lab work numbers, but chasing being in a state of feeling great everyday. Despite me having affiliations now, which BTW are vendors I research with, nothing changes about the core reason I started posting. I love this stuff. It’s all I focus on now. And it looks like I’m in the right area on X to be able to showcase it and help people as well as learn myself. I would like to be able to make an income out of this someday, but don't know how thats going to fully materialize. In real life, I’m a normal dork. I love Game of Thrones, love UFC/NFL, sometimes game a bit, love my pizza and frozen margs, and love binge watching TV series to the point it's obsessive. I am a former Surveillance and Casino Management employee, who walked away from the career in my early 30s years to pursue entrepreneurship, and initially found a skill in trading, prior to shifting my focus now to biohacking. Below are progress photos (I could only add 4, from January-almost current). My cut was from 218-171lbs, where now I’m back near 200 again, much more healthy and more lean mass. 7-MONTHS... I am about this. I am excited to see where the rest of the year brings me with increased calorie intake, as well as more research. Goal is always to have an outstanding story to tell. So far I am very thankful for: Peptide Plugs: peptideplugs.com/?ref=OPTIMIZED Biolongevity Labs: go.biolongevitylabs.com/aff_c?offer_id… Rescue Research USA: rescueresearchusa.com/?sca_ref=11636… ( Code Optimized) Elite Research USA- Whom I don’t have an affiliation with, But @trinity2pointO has been great to me, and also has an amazing research catalog I wouldn’t refer everyone to explore. Also, an additional shoutout for the friendships I have built with @peptidepirate, @ThePepGuy, @kalospepgod (PepGuide.net), @JasonXinTX, and many more I could mention, who I interact with all on here often. But thankful for them finding value in my content, and offering me an opportunity to be affiliated with them, as well as accepting ideas I have offered them as well! Excited to see the growth we all make. Rest of the day, Im taking it easy and enjoying some food with the other half, and the UFC fights tonight.. Might pop in with any updates, if my never-stop working vendors sneak in some that I don't want to miss sharing!

@KimeraChems @_9th_Life_ Yep…

@OptiNeuroBio @_9th_Life_ Buzzword IMO

@tonymission @BiohackerJake Even worse, the glucagon component actually makes you more hungry. So it’s a balancing act for reta to pull off.

@tonymission @BiohackerJake Well, reta, the glp component is 33% of total solution. In tirz, it’s 50% of the solution.

People coming from Tirz to Reta need to understand that the appetite suppression is not nearly as strong on Reta. It's estimated to be 20% that of Tirz. The deficit largely comes from increased BMR so in theory you're even eating the same amount but burning an extra 500-700kcal per day. If you expect Reta to be like Tirz + one Glucagon receptor you're going to be severely disappointed. It takes a real mindset switch for Tirz users to stop chasing this zero-appetite feeling and understand that fueling the metabolism with good food is part of sustained weight loss and muscle retention. Hunger isn't a problem in need of a solution, it's a solution to your problem.

@KimeraChems @_9th_Life_ Hospira suddenly has a cult-like following and I find it funny…

@_9th_Life_ We have tested BAC water Batch and lot coded.

@_9th_Life_ There’s plenty of others that are just as good. No need to pay a premium for the USP certificate

@Breedlove22 Good write-up. Unfortunately for most, they miss some of the best nootropics around if they strictly focus on peptides. Nootropics is an even bigger rabbit hole than peptides. Spent 35+ years trying to test anything and everything.

I've spent 6 months testing nootropic peptides... So in this thread I'll break down the 5 I run, what each one is, what it did for me, and the side effects worth knowing (THREAD): 1. Pinealon

@BiohackerJake @tonymission @ThePepGuy @trinity2pointO @peptidepirate Congrats!

Wanted to give everyone a shoutout and thank you for helping me reach 1,000 followers on X. Wanted to give a second shoutout to @tonymission, @ThePepGuy, and @trinity2pointO, and of course @peptidepirate, for also assisting my journey in growing some traction in the biohacking/fitness X community. Means a lot guys. Truly.

🧪 Phase 3 Retatrutide Clinical Trial WEEK 14 — SHOT #14 Current check-in: Weight: 332.8 → 298.2 lbs Down: 34.6 lbs BMI: 42.7 → 38.3 RHR: 74 → 64 bpm Dose: 4mg Titration: 8 weeks on 2mg, now Week 6 on 4mg Appetite suppression: 7/10 Sleep: great Side effects: nothing really notable this week Little shot day insight: Once a month at the clinic I get 4 single dose pens. Every week after I inject I have to log it in the trial app. Time of injection and where I injected. Nothing crazy, but it’s one of those small details I never would’ve thought about before joining a Phase 3 trial. Should get my 90 day bloodwork tomorrow.

@zicoreemo_ @TheCryptoDaddi According to pharma, 28 days. Reality 60 days. There’s not a lot of good research on this. One small research study showed that 45 days was about when degradation started having an impact.

@TheCryptoDaddi What is the shelf life of retatrutide after reconstitution?

Saw this detailed 24 week Retatrutide plan today and figured I would share it. I want to throw my 2 cents into the mix here. Starting at 3mg if you have NO prior GLP experience is probably a bad move. Most researchers I know see noticeable changes at 1mg weekly doses. Not only is this a safer approach but it’s money in the bank. Reta is a STRONG and EFFECTIVE peptide. But more doesn’t always = better. Every single researcher will vary on dosing. Be smart.