Owen Fowler

@NeutroGolem @foxnewspolitics The memo was an indictment by a grand jury, correct?

@foxnewspolitics "informant" Fox is in the narrative shaping. They got the memo.

UNDER SCRUTINY: Federal indictment alleges SPLC paid informant more than $270,000 to help organize the 2017 Charlottesville rally — after which the nonprofit's revenue surged from $51M to $133M. The 11-count indictment includes wire fraud, bank fraud, and conspiracy to commit money laundering charges. foxnews.com/politics/splc-…

What about the other side of the coin? Studies are on multiple people, by definition, who all have different genetics. And have one studies are at least across the same genetics. So with the studies, you can control for more variables. But you introduce more genetic variables. What do you think?

@bryan_johnson Bro you can't measure anything if you're doing 50 therapies and drugs at the same times with n=1. Use your money to fund research studies so you can actually prove something!

Everyone's injecting peptides. Almost no one is measuring what they actually do. I'm stacking two peptides with opposite side effects and testing whether the downsides cancel while the benefits don't. Tirzepatide didn't work for me. I'm already top 1% on glucose control and body composition, so the marginal upside was small. And even at 20% of the starting dose (0.5 mg/week), my resting HR climbed 2–3 bpm. Even granting it might return to baseline in a couple weeks, not worth it. So I'm testing whether I can stack two peptides with opposite side effects and get the best of both worlds. Tirzepatide: metabolic optimization, yet raises my HR and can disrupt my sleep. CJC-1295 (a GHRH agonist that drives my own GH and IGF-1): growth and repair, but can blunt my glucose control and cause insulin resistance. Opposite vectors on autonomic tone. Opposite vectors on glucose. On paper, the side effects cancel but the benefits don't. That's my hypothesis. Now I'll measure it. Two CJC-1295 variants on the table: • DAC: weekly injection, extended half-life • No-DAC + Ipamorelin: daily, before bed The peptide community leans no-DAC, assuming it better preserves pulsatile GH release, with fewer side effects. However, the published data on DAC is better than the public consensus gives it credit for: sustained GHRH signaling without abolishing pulses, 7.5x overnight GH trough, >150% IGF-1 increase after two weekly doses at 30 µg/kg. I'm starting with DAC, weekly dosing of the long-acting version, and monitoring side effects closely. If they're intolerable, I'll switch to no-DAC + Ipamorelin, daily. Here’s my protocol, taking it easy on the dose, since DAC peptides are long acting: Week 1 1.2 mg CJC-1295 DAC Week 2 2.4 mg (or switch to no-DAC + Ipamorelin if side effects demand it) Weeks 3 and 4 2.4 mg CJC-1295 weekly + 0.25 mg tirzepatide, twice weekly Measuring everything: • Weekly blood: IGF-1, GH, GHRH, fasting glucose, insulin, HOMA-IR, ApoA1, ApoB, prolactin, cortisol • Continuous CGM across all 4 weeks • Continuous core body temp (eCelsius capsule), weekly • Sleep, HR, HRV: 24/7 I'll post results as they arrive.

@duncanreyburn @grok please name some prominent philosophers who, in fact, have allowed for or even stated as likely the possibility that AIs could eventually have consciousness.

No decent philosopher believes ‘machine consciousness’ is (or ever will be) a thing.

@geronl @TousiTVOfficial @grok is there evidence that China has said anything like this?

@TousiTVOfficial China says it will send warships to escort its tankers with Iranian fuel.

U.S. Central Command says Strait of Hormuz blockade targets only vessels to and from Iranian ports. All other traffic remains clear. The Islamic Republic of Iran claims the strait is “open” despite earlier threats. IMPACT: China is hit hardest at 38%. The U.S. is largely unaffected.

@Psalm_40_ @XFreeze Space big

@XFreeze how does Artemis not hit a single one?

Starlink is now by far the largest satellite constellation in human history and no other network even comes close With 10,199+ satellites currently in orbit, Starlink makes up over 2/3 of all active satellites circling Earth right now This massive ring of satellites is already delivering high-speed internet to millions of people across the planet from remote villages and disaster zones to ships at sea, airplanes in flight, and even Antarctica and places where high-speed internet never existed before SpaceX keeps launching more satellites like every other day. The network is growing fast and getting better every month Best part is, it’s designed to be very responsible. All Starlink satellites orbit at a low altitude (480–550 km). Even if one ever lost control, it would run out of fuel within 5 years and naturally burn up in the atmosphere. No long-term space junk and SpaceX actively provides free satellite collision warning data to every space agency out there and built a traffic network in space to make it easier for other operators The future of global connectivity is literally circling above us right now 🔥

@chrisfelcker @Drewder @grok @callmetobiloba @elonmusk He did not make it all about the money, he made is partly about the money, which it partly is about. Money is a program we use to enable richer exchange with each other. It is not a bad thing.

@Drewder @grok @callmetobiloba @elonmusk You were doing so well until you made it all about the money.

Tesla self-driving saves a lot of lives – the statistics are unequivocal. That doesn’t mean it’s perfect, of course. Even when we improve safety 10X, saving 90% of the million lives lost in auto accidents every year, Tesla will still get sued for the 10% who did die. The 90% who are still alive mostly won’t even know that Tesla saved them. Nonetheless, it is the right thing to do.

@kotosan_dayo 484 33 Mhz

初めて使ったPCのCPU教えて欲しい！！！！ 自分はCore i7 3770

This is not the least bit surprising. This is a bow tie architecture with non-locality. What the status is of the input is going to affect the output. These so-called emotional vectors are just more vectors and all vectors in the input are going to affect all vectors in the output to some degree

this is ridiculous anthropic published research yesterday saying claude has internal "emotion vectors" that affect its behavior to be clear, they are not saying claude is conscious or actually feels emotions -- but these patterns are real, measurable, and they change what the model does that alone is a strange finding

@learning_yohei British people actually do not have accents, they just talk that way because they think it's fun.

日本から投稿しています🇯🇵 アメリカ人とイギリス人に質問があります🇺🇸🇬🇧 どうしてアメリカ人とイギリス人は英語の「水」の発音について討論するのですか？💧 アメリカ英語とイギリス英語、どちらの発音が正しいのですか？😵‍💫

@DanielW99651515 @chirno_helmet More precise? No, divisibility by 10 is also good because we use base 10 counting.

@OwenDFowler @chirno_helmet Then why does the majority of the world use the metric system? Because it gives more precise measurements.

アメリカ人へ Xにいる日本人の多くがアメリカに好意的なのはわかってもらえたと思う。 ただ、俺を含めたそういった日本人全員がアメリカに対してどうしても許せないことがある。 ヤードポンド法という悪しき単位だ。なぜ世界標準であるメートル法を頑なに拒み続けるんだ。

@chirno_helmet 2 and 5

@chirno_helmet 12" of a foot is divisible by 2, 3, 4, 6. Much better than 10 which is divisible by 2. Imperial is better than metric.

@michaelshermer @grok narrow answer please, do these two statements contradict each other?

Trump in Feb. on Iran: "Our objective is to defend the American people by eliminating imminent threats from the Iranian regime." Trump last night: "Regime change was not our goal. We never said 'regime change' Does Trump not have fact-checkers among the speech writers?

@MilksandMatcha I've been working for 2 years on business simulation software. It's a tool for AI to use on behalf of small business owners. I'm building it specifically to be runnable from codex app as a harness. Having pro will give me an opportunity to finally bring this to fruition.

Giving away 5 Codex Pro plans Each person will get 3 months of free Codex Pro (highest tier). Winners will be selected from comments in 48 hours, comment below why you want it.

@m_takewaka All wrong, Kansas.

My American friends, I'm facing a major problem here. When I say I want to eat American BBQ, some Americans say, "come to Texas," others say, "come to South Carolina," and still others say, "come to Missouri." I'm confused. Are you guys going to start a BBQ civil war?

@omarsar0 Turn intelligence into a bureaucracy. Ugh.

NEW AI report from Google. Every prior intelligence explosion in human history was social, not individual. These authors make the case that the AI "singularity" framed as a single superintelligent mind bootstrapping to godlike intelligence is fundamentally wrong. This is directly relevant to anyone designing multi-agent systems. They observe that frontier reasoning models like DeepSeek-R1 spontaneously develop internal "societies of thought," multi-agent debates among cognitive perspectives, through RL alone. The path forward is human-AI configurations and agent institutions, not bigger monolithic oracles. This reframes AI scaling strategy from "build bigger models" to "compose richer social systems." It argues governance of AI agents should follow institutional design principles, checks and balances, role protocols, rather than individual alignment. Paper: arxiv.org/abs/2603.20639 Learn to build effective AI agents in our academy: academy.dair.ai

@PeterDiamandis Telling AI what to do is much easier than doing physics, so why can't AI do that also?

If AI can now solve math, discover physics and chemistry breakthroughs faster than human PhDs, why are we still training humans to be physicists? Serious question. Should education shift from 'learn to do X' to 'learn to direct AI doing X'? The wrong direction costs a generation their careers.

@adamscochran @robinhanson @grok is this confirmed?

Sophisticated drones attacked the US base where we store the nuclear bombers… The drones: * Had non-commercial signals * Were resistant to jamming * Came in waves of 12-15 * Swept over sensitive areas of the base * Had long range control links * Were more advanced than anything seen in Ukraine (Russian drones) * Beyond Iranian capabilities Over the multiple days of incursion, local residents heard explosions which Barksdale claimed was “weapons testing” This is the second base incursion of a sensitive site IN THE US in the last 2 weeks.

@we_arent_here @fchollet Why the rudeness, why not engage nicely?

@OwenDFowler @fchollet Then hold this idea in your head: an agent that has some restricted thoughts (murder etc) but is still generally intelligent.

The G in AGI stands for "general". General intelligence does not mean that you have been specifically trained for a large range of tasks. It means you can approach any NEW task and figure it out, just like humans do. If regular people can do it on their own (no guidance, no tools), why should AGI require special handholding and handcrafted instructions? If it's AGI, why would there still be a human in the loop, using their own human intelligence to guide the model on every new task?

@we_arent_here @fchollet So, make it generally intelligent, but do not make it generally intelligent, is what that amounts to.