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@hubermanlab Please organize a podcast with George Lucas, @MitoPsychoBio and @jordanbpeterson about Star Wars, mitochondria, spirituality and life.
People need to know while we still can.
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Sefray
1.2K posts
Tyler you have massive negativity bias.
You focus a lot on groups and their minority of bad apples.
This way you will never "become president".
Please try alternative:
Study your topic in depth.
Show the good.
Show the bad.
Mixed in-between.
And truthful, honest and balanced view overall.
West is built on individualism.
Reject collectivism.
Have discernment.
You are not responsible for actions of small minority of fellow evil Americans.
Most people of other groups neither.
Strive for virtues.
Have some principles.
Consider faith.
We are all flawed humans.
Lets help each other become better through love, truth and good.
Justice must be righteous.
🙏
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I am running for President of the United
States in the year 2036.
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@MitoPsychoBio and I are back from Nepal after quite an illuminating experience (more to come on that).
We return with a stronger sense of purpose: bringing this community together around the science and lived experience of energy.
Join us this upcoming Tuesday as we gather again on X Space to...
....explore how we sense our energetic state, how it becomes experience, and whether understanding ourselves through an energetic lens can offer deeper insight into our health and the nature of mind.
Looking forward to regrouping with you all - see you there!
📅 Tuesday, March 24, 2026 : 12PM EST
📍 x.com/i/spaces/1RJjp…
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Thank you. ❤️
You know, it seems like flow is one of those important patterns and might be a universal one.
Another parallel of flow I found and experience is flow state or some people sometimes call it hypomania.
The strongest occasion happened to me in 2025.
There is a long boring biographical context which lead to moment where I started to really take care of myself health wise and spiritually, prayed once and then have gone into several months period of the most amazing flow state phase of my life.
Never was this energetic, creative and alive.
Won an art contest, made couple of games, wrote my first screenplay in 2 days, opened up in deep important conversations...
Faith and prayers was the key to this.
It often triggered or hightened flow state.
Was atheist/agnostic for 30+ years, but after that could not deny God anymore and started my serious spiritual journey. Have a lot of obstacles, fail often and need to learn a tone of stuff, but now slowly, but surely growing and building towards hopefully something good.
Still figuring out what it might be, it's up to His will now.
🙏
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Important concept - life needs resistance, but the right amount.
We can only live and thrive in a Goldilocks zone of energy resistance.
ERP paper here: picardlab.org/uploads/7/7/8/…
Why would I get fat?@whygetfat
The mitochondria's electron transport chain could instead be called the electron resistance chain. The magic which enabled multicellular life is there's just the right amount of resistance to extract and transform a little bit of energy as the electrons flow Nick Jikomes, PhD: "The mitochondria are little cells inside of our cells, and they've got two membranes. The inner membrane is like a little wire through which these electrons are flowing from food to oxygen, and the way it flows, and that it flows, that's how energy is getting made." Martin Picard, PhD: "That's how energy is getting transformed." Nick Jikomes, PhD: "Transformed. Yes." Martin Picard, PhD: "You get electrical energy of the electrons flowing, and then through each step in the electron transport chain, which is this a sequence of big protein complexes in the inner membrane of the mitochondria, which are like little folds, and they're so gorgeous. "So as the electrons are flowing through this, they're facing little steps of resistance in the electron transport chain, could be called maybe the electron resistance chain. But this is finely tuned by evolution so that there's just the right amount of resistance for the electrons as they flow, a little bit of energy is extracted, is transformed, and then that is used to pump a proton across the membrane. "So then you're using electrical energy, it gets transformed into this electrochemical gradient, and it's that step of transformation which I think is really the magic of life, and maybe why mitochondria enabled complex multicellular life, right, because then you go from chemical electrical energy, which comes from chemical energy, the food you ate, and then you transform this into this electrochemical charge, which is like a little voltage, which so malleable. Like the degrees of freedom, once you have stored electricity, the degrees of freedom is immense, much more than if you go from like biochemical energy. So that ability to transform biochemical energy into an electrical charge like a voltage potential, then you can power everything, the same way that electricity powers everything in our lives, from computer, phone, light, stove, washer. So we know electricity is versatile. The brain uses that as an energetic modality to integrate information." @MitoPsychoBio & @niroshajmurugan with @trikomes @ 22:14–24:19 (posted 2025-10-29) youtu.be/GiwDfsIgziA&t=…
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We've also just open-sourced Writebook fully! Help us make it better now that the repo is on GitHub. github.com/basecamp/write…
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ONCE is back! It's now a full-fledged application server for running dockerized web apps, like Campfire/Writebook/Fizzy or your own vibe-coded adventures. Zero-downtime upgrades, scheduled backups, and a gorgeous TUI with hyperdrive graphics. Enjoy! github.com/basecamp/once
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@DrBrianKeating @slatestarcodex 🤔
Looked for what bad games I'm might be playing, but do not saw anything yet.
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Moloch's Bargain
Imagine a game where every player is choosing rationally—and the outcome is catastrophic for everyone.
Essayist Scott Alexander (@slatestarcodex) named this dynamic after the Canaanite god of child sacrifice: Moloch. It describes competitive situations where individual optimization leads to collective destruction. Nuclear arms races. Social media outrage loops. Academic publish-or-perish. Everyone knows the game is broken. Nobody stops playing—because stopping unilaterally means losing.
Most systems we call “dysfunctional” are actually functioning perfectly—just not for us. They’re optimizing for their own perpetuation, not human flourishing. That distinction matters enormously when you’re trying to fix them.
You can’t win a Moloch game by playing harder. You win by changing the rules, or refusing to play.
Which Moloch’s bargain have you quietly accepted as “just how things work”? The answer is uncomfortable.
Read More at Slate Star Codex→
slatestarcodex.com/2014/07/30/med…
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Visual hyperphantasia.
Any sound, music at will.
Clear and precise internal thoughts in words.
Emotions are part of it.
Smells and taste are hardest to conjure up in mind but possible.
Can feel tactile sensations in my dreams like pain or pleasure.
Can almost feel pain from perception of pain of other people or from painful personal memories or at least get physically uncomfortable.
Intuition.
Subconscious works at all times in front and background, often gives me cool ideas at random and guides me.
There is a spiritual mystery and dynamic quality that perhaps is beyond descrete mediums.
Meditation and prayer helps with all of it.
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When you think, what medium do you tend to think in?
Would be very curious to hear how you’d describe the base unit(s) of your thoughts and how they feel to you.
I assumed what happens in my head was similar to everyone else but have been surprised by how varied thought can be.
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When God sings with his creations, will Vibecoders not be part of the choir?
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@AlisonbobEth @MitoPsychoBio @niroshajmurugan Just studied physics recently about energy and time.
Have a rough personal model that needs refinement, cause I am dumb chaotic autodidact. 😅
Wonder how it will click with health energy model.
Can't wait for Martin's book.
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Are you seeing a lot of movement, towards this newer view? It seems very obvious to me, but I understand things through a systems lens, so it’s a natural framework.
For @niroshajmurugan I jokingly say we need to move from spacetime concepts (things/parts/objects) to quantum concepts (processes/relations), to understand complex systems. A cell, a body, an earth, a universe, doesn’t matter, all follow universal patterns 💫
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Great to be back from Nepal!
In this week's first Substack article, we discuss a recent paper written with Chris Kempes on the role of energy in health and disease.
The key difference between life and death is not the physical stuff of life. It's the flow of energy.
We propose that thinking about health and disease processes energetically can unlock a meaningful transition to the next stage of evolution for biomedicine.
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@windscribecom Tempting. 🤔
To join the contest or make a sacrifice, study and work instead.
GIF
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ATTENTION ALL ANIMATORS!
You've got a chance to win THOUSANDS of dollars in our animation contest! $42,000 prize pool! Get your submissions in by April 13th!
Windscribe@windscribecom
"AI art is real art!!" "AI can only produce slop!" Enough bickering! It's time to put this to the test. Introducing the Windscribe Animated Production Fest! A contest for human and AI animations to go head to head for a prize pool of $42,000!
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@timsoret Golden rule.
If you don't want yourself being used as meat puppet for whatever bad or good purposes after your death then treat others the same.
Did Val approved it?
If not, to me this is wrong.
If he did and they doing it exactly as he allowed, it might be fine.
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Interesting moral dilemma.
I implore you, instead of having vivid gut reactions, to let them decant, and to listen to arguments from both sides thoroughly & earnestly.
Variety@Variety
FIRST LOOK: Val Kilmer has been resurrected via AI to star in the new movie "As Deep as the Grave." Kilmer was cast in the movie in 2020, five years before his death. But he was too sick amid his throat cancer battle to ever make it to set. Now an AI version of the actor is appearing in the film, with the full blessing of his daughter, Mercedes: "He always looked at emerging technologies with optimism as a tool to expand the possibilities of storytelling. This spirit is something that we are all honoring within this specific film, of which he was an integral part.” “He was the actor I wanted to play this role,” says writer-director Coerte Voorhees. “It was very much designed around him. It drew on his Native American heritage and his ties to and love of the Southwest... His family kept saying how important they thought the movie was and that Val really wanted to be a part of this. He really thought it was important story that he wanted his name on. It was that support that gave me the confidence to say, okay let’s do this. Despite the fact some people might call it controversial, this is what Val wanted.” wp.me/pc8uak-1lH1PI
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@TheCriticalDri2 Want to start saying it now:
I disapprove, discourage of digital or biological necromancy, AI cloning/mimicry/puppeteering/fake resurrections of my being, body, identity or soul in any way, shape or form.
Any artificial versions of me are fake.
Don't use my fakes. And let me go.
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Well, that's... horrifying.
Variety@Variety
FIRST LOOK: Val Kilmer has been resurrected via AI to star in the new movie "As Deep as the Grave." Kilmer was cast in the movie in 2020, five years before his death. But he was too sick amid his throat cancer battle to ever make it to set. Now an AI version of the actor is appearing in the film, with the full blessing of his daughter, Mercedes: "He always looked at emerging technologies with optimism as a tool to expand the possibilities of storytelling. This spirit is something that we are all honoring within this specific film, of which he was an integral part.” “He was the actor I wanted to play this role,” says writer-director Coerte Voorhees. “It was very much designed around him. It drew on his Native American heritage and his ties to and love of the Southwest... His family kept saying how important they thought the movie was and that Val really wanted to be a part of this. He really thought it was important story that he wanted his name on. It was that support that gave me the confidence to say, okay let’s do this. Despite the fact some people might call it controversial, this is what Val wanted.” wp.me/pc8uak-1lH1PI
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@bryan_johnson Solving aging ultimately will not save you from death.
Voldemort was fighting death too.
You have a snake as a logo.
Chinese emperor died from poisoning on his immortality quest.
Be careful with dragging other people into this. "Do no harm."
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I was in the HBOT chamber yesterday, at min 45, and remembered I’d swallowed a pill to measure my core body temp. Panic set in. Would this pill combust in my hyperoxyinatad tissues? Might this be my last moment? Surely, it will be one of these circumstances that finally gets me.
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No automation:
- no required civilizational progress.
- no needed life improvements.
- no enhancements and democratization in creative arts.
Extreme full automation:
- no challenge, effort and hard won value.
- loss of meaning, freedom and idependence.
- self-automation out of life and existence.
Let's find the proper way in the middle.
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"Canned music"
Witness the scandal when technology allowed to record music & voices, and reproduce them across time & space.
Funny how many people today sound exactly like this.
smithsonianmag.com/history/musici…
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We're happy to announce that the next release of our desktop app WILL be shipping with DLSS 5 compatibility!
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