Thomas L. Steinacker

Ending the week with an announcement of our newly-published tool for exploring 3D #genomics data and 1D genomics profiles: HiCognition! Read the paper here rdcu.be/dgjig and give it a try yourself at app.hicognition.com

@Saroj_Saurya @LPTrustUK @ArielBlocker @AnnelieseDodds @DailyInfoOxford @FrediOtto @JennerInstitute @OxfordMedSci @clvinnicombe @JaneHPMuyu @Dunn_School @UniofOxford Congratulations Saroj! Such a good effort :)

Check this out!! I had a haircut today so that I can donate my hair to the @LPTrustUK to make a wig for cancer patients. To make each wig it cost £550 & therefore I am fundraising as well. You can donate to my JustGiving page by clicking here. Please RT🙏justgiving.com/page/sarojsaur…

📣 Now #hiring! The @Gerlich_lab at IMBA seeks a scientific programmer / bioinformatician / data scientist to join its lab. 🎯 To the application: bit.ly/3VOTNY7 #CellBiology #Biology #ImageAnalysis #ComputerScience #SoftwareDevelopment #MachineLearning

The Gerlich lab is hiring! We are looking for a Research Technician to join our team @IMBA_Vienna, @viennabiocenter. For more info and to apply: imba.onlyfy.jobs/job/oawqg61s

Aydogan @mga38 @UCSF, Hankins @Co_Biologists et al @JRafflab @Dunn_School @UniofOxford discover an unexpected crosstalk during centriole biogenesis; more in our Research highlight: ow.ly/uYgW50KiAc8

Hot off the press @Nature! "A mitotic chromatin phase transition prevents perforation by microtubules". Our work on mitotic chromosome formation, a tweetorial: In #collaboration with @bryangibsonphd, @ShotaroOtsuka + the lab of Mike Rosen @UTSWNews 1/6 nature.com/articles/s4158…

From @JRaffLab, @TL_Steinacker, @ISiuShingWong, @JordanRaff and colleagues: How the phosphorylation of Ana1 by Cdk/Cyclins limits centriole duplication in flies. bit.ly/3ckjDSb @Saroj_Saurya #Biochemistry #CellCycle #CellDivision

Check out our excited work by @TL_Steinacker & @ISiuShingWong et al. on the effects of #phosphorylation on #Ana2/#STIL! It's now available @JCellBiol @RockUPress. Thanks everyone who involved in this project! 🍻🍻🍻 rupress.org/jcb/article/22…

"Centriole growth is not limited by a finite pool of components, but is limited by the Cdk1/Cyclin-dependent phosphorylation of Ana2/STIL" @TL_Steinacker @JRafflab et al @Dunn_School #RefereedPreprint #CellBiology #CellCycle reviewcommons.org/eeb/10.1101/20…

Our latest work shows centriole growth isn't controlled by the cytoplasmic depletion of its components but by a cell cycle dependent phosphorylation of Ana2. It's now available @biorxivpreprint. Well done @TL_Steinacker, @ISiuShingWong & co-workers! biorxiv.org/content/10.110…

@DunsingValentin @joachimgoedhart @Roy_Lab_Thinks @christlet I don't have any real data on this, but I think mNG is pretty stable. mNG-tagging of a low abundant protein allowed us to image it for a longer time in comparison to the GFP-tagged version.

@TL_Steinacker @joachimgoedhart @Roy_Lab_Thinks @christlet Is that compensated by higher photostability of EGFP?

Twitter, what's the latest greatest fluorophore for endogenous tagging? I heard mNeon but that was before the pandemic. @christlet

@DunsingValentin @joachimgoedhart @Roy_Lab_Thinks @christlet mNeonGreen-tagging work very well in Drosophila embryos. Using 488 nm excitation, I observe ~1.6-fold increase in brightness compared to GFP. :)

@joachimgoedhart @Roy_Lab_Thinks @christlet Maybe @TL_Steinacker can share his experience on FP tags in drosophila? :)

@s_jagal @GenesDev @juliusbrennecke Congratulations!!🥳

@IMPvienna @PaulaGuper @LCochella Congratulations!!

Congratulations to @PaulaGuper from @LCochella's lab for being presented this year's Lauwers Award for the best Monday Seminar talk! #vbcphdstudensrock imp.ac.at/news/article/l…

The big winner of our first Christmas decoration competition is @JRafflab, with their entry "O' come all ye fly vials". The judges were particularly impressed by their commitment to the @Dunn_GoGreen values, as recycled fly vials were used for this beautiful decoration!

@ju_charest @LCochella Congratulations!

We’re recruiting! Come join a young (but growing!) lab working at the intersection of cell biology and evolution to understand the organisation of the nucleus - and train in one of the world’s best PhD programmes! #EMBLPhD2021 embl.de/research/units…

📢 We are looking for outstanding early career researchers seeking mentoring and sponsorship to apply for career development fellowships @Dunn_School! 📢 We particularly welcome applicants from diverse backgrounds underrepresented at Oxford! Please RT! path.ox.ac.uk/content/cdf

Really excited to share that my PhD paper with @lcochella is out: A deeply conserved miR-1 dependent regulon supports muscle cell physiology! There are a few surprises here, check out this thread -> 1/8 biorxiv.org/content/10.110…

Read @InesDoesScience's latest preprint on how Ana1 and Polo work together in centrosome biology!