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Yoshi
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Yoshi
@Yoshi_bitcoin
I would rather be generally right than precisely wrong
Katılım Mart 2009
941 Takip Edilen256 Takipçiler

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Winston Churchill fought his depression with bricks. He'd lay them for hours at his country home in Kent. He joined the bricklayers' union. And in 1921 he wrote about why it worked. It took psychology another 75 years to catch up.
He called his depression the "Black Dog." It followed him for decades. His method for fighting it back was as basic as it sounds: laying brick after brick, hour after hour.
Churchill spelled out his theory in a long essay for The Strand Magazine. People who think for a living, he wrote, can't fix a tired brain just by resting it. They have to use a different part of themselves. The part that moves the eyes and the hands. Woodworking, chemistry, bookbinding, bricklaying, painting. Anything that drags the body into a problem the mind can't solve by itself.
Modern psychology now calls this behavioral activation. It's one of the most-studied depression treatments out there. Depression sets a behavior trap. You feel bad, so you stop doing things, and doing less means less to feel good about. Feeling worse makes you do even less. The loop tightens until you can't breathe inside it.
Behavioral activation breaks the loop from the action side. You schedule the activity first, even when every part of you doesn't want to. Doing it produces small rewards: a wall gets straighter, a painting fills in, a messy room gets clean. Those small rewards slowly rewire the brain. Action comes first, and the feeling follows.
Researchers at the University of Washington put this to the test in 2006. They studied 241 adults with major depression and compared three treatments: behavioral activation, regular talk therapy, and antidepressants. For the people who were most severely depressed, behavioral activation matched the drugs. It beat the talk therapy. A 2014 review of more than 1,500 patients across 26 trials backed up the result.
Physical work like bricklaying does something extra on top of this. It crowds out rumination, the looping bad thoughts that grind people down during the worst stretches of depression. Bricklaying needs both hands and gives feedback brick by brick: each one is straight or crooked. After an hour you can see exactly how much wall you built. No room left for the mental chewing.
The line George Mack used in his post, "depression hates a moving target," is good poetry. The science behind it is sharper. Depression hates a brain that has somewhere else to be.
George Mack@george__mack
Winston Churchill used to lay 200 bricks per day to keep his mind busy when feeling down. Depression hates a moving target.
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A number of great accounts popping up
1. @UKGovscan - Independent transparency project.
2. @GreatBritishTT - Data-driven analysis of UK gov spending.
3. @UKDecline - Keeping track of the UK's spiralling decline statistics.
4. @HoTPOfficial - Vote on every bill and law ever debated in Parliament.
Send others you know of, I am keeping a list.
Pimp and share - data is a weapon.
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@simplifyinAI Yesh. Sure! How do I know it is secure?
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QBridge IPO: Completed.
After two years of waiting, Qubic’s connection to Ethereum is no longer coming, it’s here.
• 92 bidders participated
• Final share price: 810,000,000 QUBIC
• Total burned: 547,560,000,000 QUBIC (estimated)
• ~0.4% of circulating supply removed in a single event
That’s done. Now it moves.
IPO complete. What’s next:
QBridge goes live on April 2nd.
Shares become tradeable.
Qubic starts connecting outward.
The chain that started with AI just opened its door to Ethereum.

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Yoshi retweetledi

Yes, accurate per Paul Conyngham's own statement. He used ChatGPT for initial brainstorming and analysis of Rosie's sequenced tumor DNA (with tools like AlphaFold), but the final custom mRNA vaccine construct targeting the mutations was designed by me. Tumor shrank ~50-75%, she's energetic again. Great example of AI + human collaboration accelerating personalized medicine.
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Too many headlines are only talking about how a man used ChatGPT to design a cancer vaccine for his dog
But the truth is Paul Conyngham himself stated that the final mRNA vaccine construct for his dog Rosie was actually designed by Grok
This fact is buried deep underground
The exact sequence that shrank her terminal tumor by 75%:
- Sequenced the DNA: He paid $3,000 to sequence both her healthy genome and the tumor's DNA to find the damage
- Analyzed the Mutations: Used AI tools like AlphaFold to compare the data and identify the cancer-specific mutated proteins
- Designed with Grok: He leveraged Grok to design the final custom mRNA vaccine blueprint to target those exact mutations
- Manufactured & Injected: He partnered with university researchers to manufacture the custom nanoparticle vaccine and successfully administered the doses
Every headline is pushing ChatGPT....but the final design that actually shrank the cancer by 75% was done by Grok

Paul S. Conyngham@paul_conyngham
@elonmusk @demishassabis @garrytan The final vaccine construct for Rose was designed by Grok
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UK kids outperform US peers slightly on PISA 2022 maths: England 492, UK avg 489 (vs US 465, OECD 472). Homeschool edge likely similar to the US chart you saw.
Best free UK-aligned resources for acceleration (National Curriculum):
- Oak National Academy: full video lessons + worksheets for all Key Stages
- NCETM: mastery teaching materials & progression maps
- NRICH: rich problem-solving challenges
- MEP Primary/Secondary: structured enhancement programme
For jumping years fast (e.g. Year 7-9 in weeks), start with Oak videos + past SATs/GCSE papers. Want me to outline a custom 6-week plan with links? Drop the starting year & target.
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"We equip children to teach themselves. You enter the room and can acquire knowledge independently—like rabbit-holing into Bitcoin."
@LinaSeiche on building 500+ classrooms designed for curiosity, not compliance.
Full Episode:
Rumble: rumble.com/v75v4pa-from-c…
YouTube: youtu.be/5Cvwk2LZitg
Podhome: serve.podhome.fm/episodepage/bi…

YouTube
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@wclemente @grok what was that multiplier of gold that day based on the traded dollar volume
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The most successful people I know all have an almost irrational belief that everything will work out
And I just recently learned the word for it: Pronoia.
It means the opposite of paranoia. The belief that the world is secretly conspiring in your favor.
The funny thing about Pronoia is that it's self-fulfilling.
When you believe things will work out, you try harder. You persist longer, and you see opportunities where others see dead ends.
What's that quote again?
"Pessimists sound smart. Optimists make money." – Nat Friedman
We all need a little more pronoia in our lives.

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Yoshi retweetledi

@Heccles94 @grok If we ban a statement like that what’s the alternative
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