Alessia Zotta

🤔Do you think that OXPHOS in DCs = tolerance? 🚨In our new @Cell_Metabolism study @CNIC_CARDIO , we show that active #mitochondrial ETC primes cDC1s for immunogenicity, boosting anti-tumor immunity. Life (and #immunometabolism) is not simple ⚡️(1/9) OPEN: cell.com/cell-metabolis…

#PhD in immunometabolism on fatty acid oxidation in #macrophage function. MSCA-doctoral network unimedizin-mainz.de/unlimited-msca… For our DC8 position apply in parallel in 2 sites: 1. unimedizin-mainz.de/unlimited-msca… 2. cnic.es/en/convocatori… (DC8: NOT resident >12m in Spain in last 3 years)

Don't miss the 2nd Conference of the European ImmunoMetabolism Network - EIMN2026 . 📅10-12th June 2026 📌Luxembourg immunometnet.eu @ImmunoMetEurope linkedin.com/events/2ndconf…

#WeekendRead #InterferonsFriendsOrFoes?! @RuthFranklinLab @RMedzhitov &co show @ScienceMagazine that macrophage-derived oncostatin M overcomes type I IFN detrimental effects during influenza lung infections by driving AT-II epithelial cell proliferation! science.org/doi/10.1126/sc…

Welcome to read the comments from Professor Christian Frezza @FrezzaLab and his colleague on this paper. "Macrophage respiratory complex III governs immune evasion" journals.lww.com/immunometaboli…

I'm thrilled to share that I've been awarded a 4-year postdoctoral fellowship by @Stkstichting !🥳🧪 I am grateful for the opportunity to continue my research on macrophage metabolic reprogramming, particularly in metastatic development! Excited for what's ahead!🔬🤓🥼

We are looking for 1 mid-career scientist (and postdocs) willing to join us as SR-Tiget in Milan. Basic and translational immunology, gene and cell therapy, genome/protein tech, computational biology... all welcome 💚🤍❤️ check the Call, pls RT! fondazionetelethon.it/en/what-we-do/…

‼️#NewPaperAlert ‼️ The PYRIN domain is required for TLR4-mediated inflammation by PYHIN family members. This study uncovers a unique DAMP–PRR interaction with therapeutic implications in sterile inflammatory diseases. @ousitanio @UniAvogadro 1/ cell.com/iscience/fullt…

#EducationPower! Tang &co show ⁦@ScienceTM⁩ that tumor-derived microparticles loaded with succinate re-educate tumor-associated macrophages #TAMs via #epigenetic & #metabolic reprogramming, potentiating anti-tumor responses in multiple cancer models! science.org/doi/10.1126/sc…

Beautiful story in @Nature on how metabolism plays a major role in directing liver regeneration after injury from @NabilDjouder group nature.com/articles/s4158…

Very excited to share that the work of my PhD, where we engineer T cell metabolism to improve their antitumoral activity, is finally out in ✨ @NatMetabolism 🙏Huge thank you to @MazzoneLab and all the collaborators @vib_ccb @KU_Leuven 🔍—> sulkurl.com/n0r

A wonderful insight into climbing fibers and ataxia just out in @ScienceTM from @IlaIaia93 et al. 😄🤗✌🏻👏

🚨CALL FOR ABSTRACTS!🚨 Are you studying the role of the Cerebellum in Autism? Do you use new methods, models or approaches? We want you!!👉🏼 My friend Brigitta and I had the amazing opportunity to be guest editor at @JoVEJournal and unified our passions! app.jove.com/methods-collec…?

Massive congratulations to @AlvaCasey3 on her first author paper from her PhD: 'Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation' #immunometabolism nature.com/articles/s4225…

🚨 Fully Funded PhD Opportunity! 🚨 As part of UNION, we are offering one PhD, starting Sept 2025, exploring cross-tissue B cell metabolism in age-related diseases and cancer🔬🧬 🌍 2 rotations in top European labs
📅 Funded through @MSCActions DM for details! 📩 #PhDPosition

Massive work from Jess Spinelli @UMassChan demonstrating a SECOND electron carrier in the mammalian ETC cell.com/cell/fulltext/…

Mitochondrial respiratory complex III sustains IL-10 production in activated macrophages and promotes tumor-mediated immune evasion science.org/doi/full/10.11…

Thanks for sharing! #immunometabolism #tumor #immunity

Mitochondrial fatty acid oxidation is essential for the epigenetic control of type I interferon signaling @ScienceAdvances science.org/doi/10.1126/sc…

Thrilled to share the work of my PhD,out in @ScienceAdvances!🥳We discovered that complex III regulates IL-10 production in macrophages and its targeting decreases tumor growth in mice🧫Grazie a Luke,LON Lab & collaborators🔬 #immunometabolism #lover👇 science.org/doi/10.1126/sc…