James

Easter Sunday 2026, Artificial General Intelligence has risen

I have never been so bullish on the United States of America.

1/ Insane: A single injection into the inner ear reversed deafness in all ten patients. Some started hearing again within weeks. Gene therapy just crossed a threshold we thought was still years away. Lets dig into this breakthrough and how it works 🧵

@AndreasSteno @MickF1 @DavidD_Chapman Canada has itself committed $25B towards Ukraine war, ramping up recently.

@MickF1 @DavidD_Chapman No US funding at all

Withdraw from NATO and withdraw all US troops from US bases in Europe and see how many days it takes Russia to conquer Europe.

Medicine is shifting from reactive to predictive

My dear front-end developers (and anyone who’s interested in the future of interfaces): I have crawled through depths of hell to bring you, for the foreseeable years, one of the more important foundational pieces of UI engineering (if not in implementation then certainly at least in concept): Fast, accurate and comprehensive userland text measurement algorithm in pure TypeScript, usable for laying out entire web pages without CSS, bypassing DOM measurements and reflow

OH “compute markets are basically competing to buy time to talk to digital god”

These two photographs are separated by only 66 years.

A CEO from one of our portfolio companies shared this with their team. I’m re-sharing it with their permission, because it resonated and reflects what all founders and CEOs should be communicating. -- We are living through a period of compounding change. And in moments like this, the biggest risk is no longer making the wrong decision. It is moving too slowly while the world moves around you. There are two paths. We can play defense: - Protect what we have - Optimize what works - Wait for clarity It feels safe. It isn’t. Or we can play offense: - Learn faster than the environment changes - Use new tools to solve old problems in better ways - And create entirely new strategies and businesses That’s where the opportunity is. Challenge yourself to do things faster and better than you have ever attempted. Stay uncomfortable. Stay on the front foot.

The awkward truth is that what counts as a good engineer just became a different thing in the last 4 months

this is why they’ve shut sora down.

@ShaziGoalie Eatons Centre also full, but no one walking out with shopping bags. Toronto folks just stretching after winter hibernation.

Spoke to a Toronto realtor today. Open houses are busy. Lots of showings booked. But offers just aren’t coming in. Buyers are showing up, taking a look and then walking away.

ENTRY LEVEL JOB MARKET WORST IN 37 YEARS PER FORTUNE

The astroturf war on AI begins

@kevinroose what models and prompts did you use?

We made a blind taste test to see whether NYT readers prefer human writing or AI writing. 86,000 people have taken it so far, and the results are fascinating. Overall, 54% of quiz-takers prefer AI. A real moment! nytimes.com/interactive/20…

insane sequence of statements buried in an Alibaba tech report

Striking image from the new Anthropic labor market impact report.

Top mathematician Don Knuth is losing his mind because Claude solved an open problem he'd been working on for weeks

My friend who is a CTO of a 50-person $100M ARR startup: "We used to hire 2 juniors for every senior. We’ve hired 0 juniors since 2024. The seniors are 3x more productive with AI. I don’t even have a pipeline of junior hires anymore"