Ace Bryan Sotelo Cabal

Gut microbes affect #cognition during #ageing nature.com/articles/d4158… #GutMicrobiome #Aging

Excited to share our new review article published today in @mbiojournal discussing the role of viral toxins in pathogenesis and dissemination. We summarize our recent work and current literature on flavivirus NS1, SARS-CoV-2 Spike, CCHFV GP38, and EBOV GP. journals.asm.org/doi/10.1128/mb…

Influenza virus hitches a cellular ride to the heart: Cell Host & Microbe cell.com/cell-host-micr…

Thanks to its extensive intrinsic neural networks spanning its entire length, the gastrointestinal tract has long been recognized for its ability to operate independently of the central nervous system Find out more about what's new @APSPhysiology: tinyurl.com/4rphwxaf

A recent study in Nature Communications reveals over 250 metabolic enzymes located directly on chromatin, a discovery that vastly expands the previously known count of only about 20. nature.com/articles/s4146…

How diet affects the gut epithelial barrier ift.onlinelibrary.wiley.com/doi/full/10.11…

Before polio vaccines Is THIS what we want to go back to?

6 year ago today, Dr. Li Wenliang passed away of COVID-19. He warned the world about a virus outbreak in Wuhan. The government silenced him. The rest is history.

A Sticky Dance Between a Cell and a Neuron. #neuroscience #science #mysterious #HiddenWorld #cell #FluorescenceFriday ➡️A Schwann cell precursor interacting with sensory axons 🔬🧫

What if our gut bacteria inject proteins into our cells that modulate our immune response? New findings show that 80% of Pseudomonadota from healthy gut microbiomes also have intact type III secretion systems @NatureMicrobiol  tinyurl.com/4v9crswh

The vagus nerve (again), here connecting the dots between sleep disturbance and gastrointestinal dysfunction cell.com/cell-stem-cell… More on this remarkable circuitry erictopol.substack.com/p/vagus-nerve-…

Emerging findings help us understand better why dietary fiber is so central to improving gut and immune health Dietary fiber supports mucosal immune function, via intestinal Segmented Filamentous Bacteria: @MucosalImmunol tinyurl.com/3fd74mr8

💪 Muscle cells merging in real time You’re watching one of [in my opinion] the coolest things your body does without you ever noticing (muscle precursor cells literally fusing into one long, powerful fiber). 🔵 Alignment: individual myoblasts migrate and line up like they’re preparing for formation 🟢 Recognition: cells “sense” compatible neighbors through surface proteins 🟡 Contact: membranes begin to thin and synchronize their signaling 🟠 Fusion: boundaries dissolve and nuclei gather inside a shared cytoplasm 🔴 Strengthening: the new multinucleated fiber becomes the machinery that lets you lift, run, and repair The glowing green nuclei are each a tiny command center contributed by a merging cell. The red signal traces the membranes as they stretch, touch, and finally blend into a unified structure. This is how muscles grow and regenerate - i.e. this is "strength" engineerednat the cellular level Credit: Yue Lu, Elizabeth Chen Lab

First test of partial epigenetic reprogramming to reverse aging for two eye conditions (glaucoma and NAION) gets FDA go ahead @lifebiosciences Based on 2020 @Nature paper pubmed.ncbi.nlm.nih.gov/33268865/ endpoints.news/exclusive-fda-…

Fascinating study on the relationship between all cause mortality and different types of physical exercise. I'll keep walking! bmjmedicine.bmj.com/content/5/1/e0…

Healthy people should take probiotics: science or hype? Available evidence supports the use of probiotics for: 🔸 Preventing antibiotic-associated diarrhea 🔸 Alleviating some minor gut issues 🔸 Improve lactose intolerance via @ISAPPscience

Incredible results out today. The same mRNA technology used in COVID vaccines- is now cutting melanoma recurrence and death nearly in HALF by training the immune system to recognize cancer. This is why we fund science and support mRNA technology.

Wow! Someone is already trying to rename blebbisomes! That took less than a year! sciencedirect.com/science/articl…

Can GLP-1 drugs reduce the incidence of cancer, independent of weight loss? Results from cohort studies are encouraging for many types (Figure) and clinical trials are ongoing @NatureCancer nature.com/articles/s4301…

HPAI infection in pregnant mice has severe consequences: In utero transmission, virus in uterus, placenta, and fetus. Offspring w decreased size, neurodevelopmental delays, + adolescent behavioral impairments. 👉biorxiv.org/content/10.110…