BrewJohnson

@ReaLtimes69 @grok what movie is this?

🇺🇸 The Best Western Opening Scene Ever 👍🤠

@jefferydhughes @speedrun World class founders with bold ideas (and ideally some traction)

@brewjohnson @speedrun Love to learn more about what they’re looking for

friends/ex-colleagues — if anyone wants an intro to the a16z speedrun team, please email/DM me! @speedrun is a combination of founder boot camp + summer camp. Incredibly valuable and fun!

@aakashgupta @grok how common is this?

What's eating her cornea is Acanthamoeba, a free-living amoeba that lives in tap water on every inhabited continent. The mechanism is what makes it a nightmare. Acanthamoeba latches onto the corneal epithelium, then burrows into the stroma and digests it one layer at a time. When drops or the immune response turn the environment hostile, it encysts. The cyst wall is nearly chemical-proof. Every time a cyst breaks dormancy, the active amoeba resumes feeding, and the treatment clock resets. Standard regimen is hourly antiseptic drops for 6 to 12 months. Published cases run 14. Pain is the clinical signature, described as out of proportion to visible damage because Acanthamoeba inflames the corneal nerves directly. Many patients stay on trigeminal nerve-pain medication for life after the infection clears. If drops fail, the next step is therapeutic penetrating keratoplasty. A cornea transplant. Recurrence at the graft-host junction runs 10 to 41%, so patients often cycle through two or three grafts. A documented fraction eventually asks for enucleation because the nerve pain is worse than losing the eye. Now the part the "Dominican water" framing buries. Chicago-area tap water has tested positive for a highly virulent Acanthamoeba strain linked to a regional spike in AK cases. CDC prevention guidance is identical for Los Angeles and Santo Domingo: never shower in contacts, never rinse a case with tap water, never swim in them, never wear them overnight. About 45 million Americans wear contacts. 99% admit at least one hygiene risk behavior. In a CDC-reviewed Iowa cohort, 17.5% of AK cases reported showering in lenses and 12.7% had rinsed cases with tap water. Initial misdiagnosis happens in 75 to 90% of cases because AK mimics herpes, fungal, and bacterial keratitis. Average interval from first symptom to diagnosis in that Iowa cohort was 1.2 months. 41% of those patients were legally blind in the affected eye before the right diagnosis landed. The risk she took is one 45 million Americans take in their own showers every week.

Dear President Trump, Thomas Sowell is an American treasure. Please consider honoring him with the Presidential Medal of Freedom. I can’t think of a greater representative of American values.

A grand jury indicted the SPLC on 11 felony counts of wire fraud, bank fraud and money laundering. I don’t know if they are guilty of these charges, but I do know the group is a money grabbing slander machine:

@pmarca found some more

Found the Nazis.

@beyondmach5 @speedrun should be open

@brewjohnson @speedrun DMs?

@kevinlewis4801 @speedrun shoot me a dm

@brewjohnson @speedrun Would love an intro for speedrun

@kcjr82 @speedrun this is true

@brewjohnson @speedrun Lots of scouts for speedrun

@DataChaz reminds me of the “kramer pants story" share.google/vqeiyFAha15M8S…

@BrianNorgard @standardsubsea @cwamidon Next time you’re in the Gundo stop by the Loan Labs office. would love to catch up.

This is Scout, a USV from @standardsubsea of El Segundo, CA founded by @cwamidon. One of the most impressive young companies building to secure our maritime future. Yet another example of what’s happening is South Los Angeles.

i am dying reading through @pmarca’s tweets from the past couple days. the whole series on introspection is a masterpiece. so many classics.

@pmarca 🤣🤣🤣🤣🤣

@YengT9 let's go lekondo!!!

"the greatest modern medical scandal since lobotomies." @geraldposner on the ongoing controversy over gender affirming care, an ideological movement about to collapse under the weight of lawsuits by detransitioners who want their mutilated bodies back. nypost.com/2026/02/09/opi…

The end state of California’s “restorative justice” experiment is sacrificing all the commons so criminals aren’t ever inconvenienced by consequences.

This is absolutely insane Democrats increased the number of middle managers at the City of San Diego by 461% from 70 in 2015 to 373 today These are government positions paid for by taxpayers for things like “homelessness, climate change, sustainability and more” “The number of middle managers at the city of San Diego has increased by 461% since 2015, while the city's population increased by just 1%. In fact, middle manager positions grew 23 times faster than the number of frontline workers, which also increased over that period — the city created new unclassified positions to be more innovative in the areas of homelessness, climate change, sustainability and more. And now, according to a report from the City of San Diego, the city has twice the number of middle managers as Los Angeles on a percentage of workforce basis.” - Richard Bailey, former Mayor Coronado

Last high school football game at the Lions All Star game 60th annual game. Flew around all day disrupting the other team. Was number 44 in blue. #hungry #Dline #classof2026 #uncommitted

@Nexxa_AI @constructcap @a16z So glad I could be along for the ride. I'm sure you could have done it without me, but then again, maybe not?

We’ve raised a $9M Seed round to accelerate specialized AI for heavy industries. This round was led by @constructcap with significant participation from @a16z speedrun, alongside our incredible existing investors. →Total funding now stands at $14M! Huge thanks to our customers, partners, investors, and especially our team. The work to modernize heavy industry is just getting started. Read more: lnkd.in/gzYcxTsV @PlugandPlayTC @PropellerOcean @untappedvcLA @beat_ventures