Sabine D. Brookman-May

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Sabine D. Brookman-May

Sabine D. Brookman-May

@brookmans76

Professor of Urology @LMU_Muenchen, SVP Therapeutic Area Head Urologic Oncology @AuraBiosciences - former VP R&D J&J - Sports Medicine 🚵‍♀️Passionate Cyclist

Regensburg/Germany, Boston/US Katılım Şubat 2013
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Sabine D. Brookman-May retweetledi
UroToday.com
UroToday.com@urotoday·
Discussion on patient selection for radioligand therapy in #ProstateCancer. Oliver Sartor, MD @EJHospital and @DanielPetrylak @YaleCancer, join @neerajaiims @huntsmancancer the art and science of selecting patients for PSMA radioligand therapy in #mCRPC. They discuss using PSMA PET SUVmean, genomics, disease sites (strong for nodes/bone, weak for liver), and clinical factors like hemoglobin and renal function—underscoring that lesions with uptake below liver should generally not get RLT and that earlier, individualized treatment yields better outcomes. #WatchNow > bit.ly/3ZAzEJ6
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Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
So important to get the right treatments developed for upper tract disease #UTUC Looking forward to seeing more trials in this indication as we need an organ sparing approach here #Dabogratinib might offer a great option to treat these patients given the high rate of #FGFR3 alterations in UTUC + the improved safety profile compared to unselective FGFRinhibitors #UTUC #FGFR3 @oncodaily #SURF303 @TyraBiosciences #UrothelialCarcinoma
Tyra Biosciences@TyraBiosciences

Last week at #EAU26, our team connected with industry peers across the #UrologicOncology community and engaged in discussions shaping the future of patient care. We look forward to continued collaboration looking forward. @Uroweb #TyraBiosciences

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Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
Great project and publication @LawenTarek ➡️ leading to several subsequent questions on the potential causal relationship between low testosterone and GG3 progression in men with #ProstateCancer on #ActiveSurveillance What are the underlying hypothesis? ❓selection of androgen-insensitive/less-dependent clones? ❓association of low T with other causative factors such as metabolic syndrome, obesity, inflammation? ❓no causal relationship but association with reduced #PhysicalActivity, frailty, age, less immune-surveillance? Would be great to see more data on this topic and specific assessments of biomarkers, longitudinal T, molecular status overall, lifestyle factors #ProstateCancer #ActiveSurveillance #Testosterone @oncodaily @JUrology @urotoday
Tarek Lawen, MD | Urology@LawenTarek

Beyond proud to have published this project in the Journal of Urology (@JUrology)! Grateful for the outstanding team that made this possible and excited to continue building on these ideas! auajournals.org/doi/abs/10.109… @UTMDAnderson @SUO_YUO @JCO_ASCO

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Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
After our session at #EAU26 I met with Jeremy Bellaiche from shuf.ai to integrate the main messages on physical exercise and cognitive performance in a short #podcast. Very nice experience to start with and hope to work together on more topics in the future! Great tool for MDs to generate informative and individualized podcasts @jeremy02766919 shuf.ai #PhysicalExercise #CognitiveFunction #Exercisumab #BrainFertilizer @uroweb 👉shuf.ai/episode-player…
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Sabine D. Brookman-May@brookmans76

After a short exercise session this morning, I was very honored to join a great panel on the topic of physician‘s wellbeing and sustainable performance at #EAU26 and talk about the significant positive impact of physical exercise on #cognitive function and resilience - beyond all well known impact on life span, health span, cancer and chronic diseases #PhysicalExercise #BrainFertilizer #Exercisumab @Uroweb @UroDoco @drphil_urology @carme_mir1 @JLVasquez82 #JasonHowlett @urotoday

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Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
Excellent summary on #NMIBC and #UTUC treatment, diagnostics and biomarkers from #EAU26 by Joost Boormans 👉urosource.uroweb.org/resource-centr… Key takeaways on #NMIBC and #utDNA/urine biomarkers 👇 ☑️#Erdafitinib-iDRS shows strong activity as ablative treatment in FGFR-altered IR-NMIBC → 6-month CR rate: 89% + as adjuvant treatment in BCG-treated HR-NMIBC, adjuvant erdafitinib shows → 1-year RFS: 83% ☑️#utDNA highly prognostic → patients #MRD-negative at baseline and week 12 had ~100% 1-yr RFS #THOR2 ☑️For HR-NMIBC, strategies that may shape future care are optimized intravesical therapy (e.g. BCG + MMC) + biomarker-guided surveillance ➡️opens promising perspectives for biomarker-guided follow-up and treatment decisions #NMIBC #BladderCancer #UroOnc @oncodaily @Uroweb @urotoday
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Sabine D. Brookman-May retweetledi
Zach Klaassen
Zach Klaassen@zklaassen_md·
First-in-human Nectin4-targeted fluorescence imaging for TURBT #EAU26 @urotoday • Diagnostic accuracy: 96% vs 85.6% with WLC • Tumor margin detection: 91.1% vs 72.2% • Ex vivo biopsy accuracy: 96.3% • Preclinical models doubled complete resection rates Probe demonstrated a favorable safety profile
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EAU Young Academics
EAU Young Academics@EAUYAUrology·
Young urologists are not just the future of our field—they are shaping it today. The Young Academics of Urology works to strengthen the scientific foundation, research skills, and international collaboration of the next generation of urologists. #Urology #YAU #EAU26
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Phillip Pierorazio
Phillip Pierorazio@drphil_urology·
@brookmans76 Wonderfully fun/insightful session Insights from amazing colleagues on sustainability of a surgical career - understand & honor CORE VALUES, create structure in life - make time for physical/mental health (sleep well) - understand that ADVERSE EVENTS will affect you, be prepared
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Sabine D. Brookman-May retweetledi
Matt Cooperberg
Matt Cooperberg@dr_coops·
Monique Roobol #eau26 wonderful update on PRAISE-U; RCT vs real world implementation of #prostatecancer screening across the EU @Uroweb
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Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
After a short exercise session this morning, I was very honored to join a great panel on the topic of physician‘s wellbeing and sustainable performance at #EAU26 and talk about the significant positive impact of physical exercise on #cognitive function and resilience - beyond all well known impact on life span, health span, cancer and chronic diseases #PhysicalExercise #BrainFertilizer #Exercisumab @Uroweb @UroDoco @drphil_urology @carme_mir1 @JLVasquez82 #JasonHowlett @urotoday
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