Sabine D. Brookman-May

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Sabine D. Brookman-May

Sabine D. Brookman-May

@brookmans76

Professor of Urology @LMU_Muenchen, SVP Therapeutic Area Head Urologic Oncology @AuraBiosciences - former VP R&D J&J - Sports Medicine 🚵‍♀️Passionate Cyclist

Regensburg/Germany, Boston/US Katılım Şubat 2013
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Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
I am very happy to share that I am starting a new role today, as VP Global Head of Clinical Development at Curium - a deliberate move to re-focus on #ProstateCancer (and beyond) and to expand into #RadioligandTherapy (#RLT) and precision Imaging. At Curium, I’ll be leading global clinical development across the radiopharmaceutical portfolio, from early innovation to registrational strategy. Next up: smarter trials, better patient selection, true integration of diagnostics + therapeutics - and most importantly, proving outcomes that meaningfully improve patient benefit. I look forward to working with many of you again! #ProstateCancer #RLT #PSMA #UrologicOncology #ClinicalTrials @oncodaily
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Sabine D. Brookman-May retweetledi
Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
As the Clinical Lead at J&J at that time writing the #PROTEUS protocol and defining the specific PET-based MFS endpoint, I am curious to see the final official results at ASCO as well. A few considerations: 🔵 As #PSMA PET imaging was not integrated in the study from the beginning, this endpoint will only be available for a subset of patients 🔵 PET based #MFS is defined in a specific way for PROTEUS as aligned with the FDA - not every positive PET scan counted 🔵 Subsequent therapy is important to consider which is often initiated prior to reaching conventional MFS 🔵 QoL is one key aspect to consider. Concerning erectile function, I’d expect that in cases with nerve sparing surgery and perioperative function (limited subset in a HR setting) recovery will be good ➡️ We will need to consider PROTEUS results together with results from other trials in this early setting including the #BCR setting ➡️ Finally, it will be most important to develop treatment strategies for patients resulting in as much as possible Freedom From Clinical Deterioration (FFCD) with as limited as possible subsequent treatment needed - new endpoints are needed! @ChrisSweens1 @oncodaily @AttardLab @DrPaulNguyen #RadicalProstatectomy #ProstateCancer @TylerSbrt
Tyler Seibert MD PhD@TylerSbrt

Important considerations for Proteus as #ASCO26 approaches 👇🏼 MFS is a challenging endpoint when we have PSMA PET available (whether it counts as an event or not)

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Eric Topol
Eric Topol@EricTopol·
What is the most established intervention linked to lower biological (epigenetic) age? Exercise A new systematic review @LancetLongevity of 44 studies, >145,000 participants thelancet.com/journals/lanhl…
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Tyler Seibert - tmp account. Go follow @TylerSbrt
Oncology friends 🌍🌏🌎 🙏🏼 share 📸 while out 🏃🏼🏃🏽‍♀️🚶🏿‍♂️🚴🏾‍♀️⛷️🏂🏄🏽‍♀️ 🌊🏝️☀️🏔️🌳🌻🌧️❄️ 🏃🏼by💧 @aadel_chaudhuri @scserendipity1 @_ShankarSiva @SimonMDLord @ethansgrumps @cwspeers @shiv_smith @lauren_henke @ResearchWyatt @mleapman @PaulSargos @SimonLo21054188 @NiuSanford @alison_tree
Tyler Seibert - tmp account. Go follow @TylerSbrt tweet media
Tyler Seibert - tmp account. Go follow @TylerSbrt@TylerSbrt7

🥇First post with new account has to be:🏃🏼 by 💧 #EAU26 (#ProstateCancer #radonc content coming soon)

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Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
I didn’t go there with the bike but took my bike with me in the car to go cycling there. It was a conference where I gave talk for the Bavarian Urologists and decided to go for a ride 🚴‍♀️ just in between. Great and lovely area there with the monastery on an island in a small lake 😁🏔️ - but great idea also to cycle to the monastery- maybe next time
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Tyler Seibert MD PhD
Tyler Seibert MD PhD@TylerSbrt·
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Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
Thank you Simon! Did a 50th birthday cycling performance test ride today to see whether I get significantly worse at the age of 50 - which was not the case thankfully 😁 + I got a table football as a birthday present for my post-cycling workout 🚴‍♀️⚽️❤️ #Cycling #Roadbike #Football #Soccer
Sabine D. Brookman-May tweet mediaSabine D. Brookman-May tweet mediaSabine D. Brookman-May tweet mediaSabine D. Brookman-May tweet media
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Sabine D. Brookman-May
Sabine D. Brookman-May@brookmans76·
Published my first paper without #urology or #oncology but with pure #sportsmedicine/neurological focus in @Muscles_MDPI 👉 A scoping review on Physical Exercise and its effects on cognitive performance and Neurobiological Markers #PhysicalExerciseAsBrainFertilizer #ExerciseAsMedicine ✅ Findings highlight skeletal muscle as an active endocrine and metabolic organ, with acute contraction-induced signaling (e.g., myokines, lactate, catecholamines, BDNF) representing a plausible mechanistic link between exercise and cognitive enhancement ✅ Available evidence positions acute exercise as a reliable, rapidly acting strategy to enhance cognitive performance, with promising implications for learning, occupational functioning, rehabilitation, and healthy aging #PhysicalExercise #Muscle #Learning #HealthyAging #BDNF
Sabine D. Brookman-May tweet mediaSabine D. Brookman-May tweet mediaSabine D. Brookman-May tweet mediaSabine D. Brookman-May tweet media
Muscles MDPI@Muscles_MDPI

🌍⚡ Research Alert🌱💡 📄 Title: Acute Skeletal Muscle Activation Through Physical Exercise and Its Effects on Cognitive Performance and Neurobiological Markers in Adults: A Scoping Review 🔗 Read it here:mdpi.com/2813-0413/5/2/… #skeletalmuscle #neuromuscular

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