Richard Scott

@JohnRMontford @kramer_holly Non-invasive measurements using a regular upper-arm cuff can accurately measure intra-arterial waveforms, including people with bad vascular disease without risks associated with an invasive measurement! Blue = invasive aortic catheter Green = calculated aortic waveform

@pash22 @Mihir_Kelshiker Is it false economy to avoid 15 seconds of screening early vs the impact on the medical system when these patients hit A&E in crisis?

AI stethoscope trial by @Mihir_Kelshiker et al highlights the perils of implementation gaps: When used as intended, an AI stethoscope enhanced the detection of cardiovascular disease — but low uptake and workflow challenges hampered effectiveness in a large pragmatic trial. nature.com/articles/d4159… via #KarenOLeary & @NatureMedicine @Coronary4front @gbiondizoccai

@elonmusk Have you considered a donation to cover SNAP funding for November? A great way to show you are for the American people.

This #NationalStrokeWeek, remember: 1 in 3 strokes is linked to undetected AF. The #UscomBP+ identifies AF risk in under 1 minute using a regular cuff. Let’s make stroke prevention part of routine care. 👉uscom.com.au #StrokePrevention @StrokeF @doingnz

From nature.com/articles/jhh20… Arterial waveform parameters in a large, population-based sample of adults: relationships with ethnicity and lifestyle factors. Abstract Little is known about how aortic waveform parameters vary with ethnicity and lifestyle factors. We investigated these issues in a large, population-based sample. We carried out a cross-sectional analysis of 4798 men and women, aged 50–84 years from Auckland, New Zealand. Participants were 3961 European, 321 Pacific, 266 Maori and 250 South Asian people. We assessed modifiable lifestyle factors via questionnaires, and measured body mass index (BMI) and brachial blood pressure (BP). Suprasystolic oscillometry was used to derive aortic pressure, from which several haemodynamic parameters were calculated. Heavy alcohol consumption and BMI were positively related to most waveform parameters. Current smokers had higher levels of aortic augmentation index than non-smokers (difference=3.7%, P<0.0001). Aortic waveform parameters, controlling for demographics, antihypertensives, diabetes and cardiovascular disease (CVD), were higher in non-Europeans than in Europeans. Further adjustment for brachial BP or lifestyle factors (particularly BMI) reduced many differences but several remained. Despite even further adjustment for mean arterial pressure, pulse rate, height and total:high-density lipoprotein cholesterol, compared with Europeans, South Asians had higher levels of all measured aortic waveform parameters (for example, for backward pressure amplitude: β=1.5 mm Hg; P<0.0001), whereas Pacific people had 9% higher loge (excess pressure integral) (P<0.0001). In conclusion, aortic waveform parameters varied with ethnicity in line with the greater prevalence of CVD among non-white populations. Generally, this was true even after accounting for brachial BP, suggesting that waveform parameters may have increased usefulness in capturing ethnic variations in cardiovascular risk. Heavy alcohol consumption, smoking and especially BMI may partially contribute to elevated levels of these parameters

South Asian: 🫀⬇️ skeletal muscle 🫀⬇️ energy expenditure even when control for difference in muscle mass 🫀⬇️ brown fat volumes in skeletal muscles (🥶) 🫀⬆️ inflammation Compared with Dutch controls Differing metabolic phenotype #EASCongress2025

@DrMarthaGulati @WHA @BaimInstitute @GoRedForWomen @dranulala @ShrillaB @aayshacader @mchonig @pnatarajanmd @Drroxmehran @PamTaubMD @ASPCardio @AnastasiaSMihai @WomensHeartCS BP = SV x HR x SVR Different Stroke Volume, Heart Rate and Systemic Vascular Resistance achieve same Blood Pressure Superficial "no BP difference" is not the same as demonstrating "equal CVD risk"!🤔 Measure underpinning physiological differences. Women not small men. @Uscom

During #HeartMonth it is important we recognize what needs to change in our clinical trials 📌include more women in trials 📌report the analysis by sex: even if no difference, we need to know that #goredforwomen #inclusion #clinicaltrials @WHA @BaimInstitute @GoRedForWomen

@Uscom For those who attend #ArabHealth, this is your opportunity get a Cardiovascular Assessment with the @Uscom BP+. See how easy it is to use in everyday clinical use wherever you are measuring legacy cuff BP.

We are excited to announce that Uscom will be showcasing our innovative medical products at the upcoming #ArabHealth exhibition, taking place in Dubai between 27-30th of January. Visit us at the national stand of Hungary SA.F55! #Uscomconference #Arabhealth2025 #Uscom

@Hragy @hvanspall @CircAHA @josephahill Good evidence #RDN helps #hypertension, but the challenge remains to identify in advance who will benefit. #PulseWaveAnalaysis and #PulseWavePhenotypes need to be explored to improve patient selection. e.g. @Uscom BP+ differentiates physiologic state between people with same BP.

@hvanspall @CircAHA @josephahill Renal denervation?

What’s new in #Antihypertensive therapies? 📍Aldosterone synthase inhibitors 📍Angiotensinogen targeted therapies 📍GLP1/GIP receptor agonists 📍Natriuretic peptide 1 receptor agonists And more.. @CircAHA @josephahill buff.ly/4h45ULk ahajournals.org/doi/epub/10.11…

Measure non-invasive central blood pressure with pulse wave analysis, including SEVR for an estimate of V02 Max and better predictor of CVD risk with a simple, objective and automated 42 second cuff measurement. At the same time evaluation of valve function, risk of AFib and differentiate between people with similar brachial BP, but very different central BP and different vascular tone (stiffness).

Someone asked me a great question: If I could only test 5 things on a patient to assess their cardiovascular risk what would they be? My answer: 1. V02 Max 2. APOB 3. Insulin Kinetics 4. Blood Pressure 5. Visceral Fat I would optimise these first.

@HRIAust @ProfJRMcMullen Consider @Uscom BP+ to screen early for risk of AF and other CVD. A regular cuff BP measurement has lots of unused clinically relevant information. See detailed pulse pressure rhythm trace for early warning of AF risk long before becoming ED statistic!

Don't miss our next Heart to Heart #seminar on Dec 3! Join us in person at HRI, or online, and learn more about the amazing @ProfJRMcMullen. You'll also meet Warren Williams – an athlete with lived experience of AF and cardiac arrest. RSVP Now: bit.ly/4dAwTgQ

@DrRaniKhatib What would be interesting is understanding who benefits the most. Mean improvement is great, but there must be some achieving significantly better than the mean, some less than the mean. Consider @Uscom BP+ to improve discrimination with upper arm cuff measurements.

The future of managing hypertension?

@SABOURETCardio @AdrianZidaritz @_Woman_health @worldheartfed @UlrichJvV @ecocardio_cl @BirkhoelzerS @kevinnbass @LittleHeartMD @TomVargheseJr @FCademartiri @minhaskh @HeartOTXHeartMD @Dr_Khan @KhaledAliMD @RichardEudes @richardvalente3 @ammr @Sarah_Moharem @AlexMebazaa @jameslhbartlett @AnastasiaSMihai

@AdrianZidaritz @_Woman_health @worldheartfed @UlrichJvV @ecocardio_cl @BirkhoelzerS @kevinnbass @LittleHeartMD @TomVargheseJr @FCademartiri @minhaskh @HeartOTXHeartMD @Dr_Khan @KhaledAliMD @RichardEudes @doingnz @richardvalente3 @ammr @Sarah_Moharem @AlexMebazaa @jameslhbartlett

Call to action for Acute Myocardial Infarction in women: international multidisciplinary practical roadmap #EHJOpen clean copy soon available ☀️ academic.oup.com/ehjopen/advanc…

@Paddy_Barrett The difference between telling people exercise is beneficial vs. showing the the benefits. Graph shows dramatic change in peripheral artery stiffness with walking 🚶‍♂️ 🚶‍♀️. Numerically in AI % drop and visual change in pulse shape. @Uscom @BPplusPWA

As a cardiologist I meet so many people who think they cannot be active if they don't run. What they often do not realise is that, for most people, an hour's walk is pretty much as good as a 5 km run. And will almost certainly keep them in the right exercise zone.

@EricTopol why do we continue to only use cuff SYS/DIA when so much more is possible?

If you thought there prevalence of cardiovascular conditions in the US was declining, think again. ahajournals.org/doi/epdf/10.11…

@EricTopol from the AHA article... we can see lowering lipids is not achieving the desired results!

@EricTopol Central aortic BP has long been an indicator of risk over and above cuff BP. e.g. from Hypertension.

We need to eliminate the MYTH people with the same upper arm cuff blood pressure have the same CVD risks. Regular cuff measurements can easily and routinely collect additional clinically useful data that differentiates between people with similar BP. This is possible today. No need to wait for a future innovation to make this possible! @Uscom BP+

There should be more information on screening for irregular rhythms and risk of stroke. @Uscom BP+ measures detailed pulse pressure rhythm waveforms and morphology not available on any other cuff based BP monitor. Every time you measure BP you can get a risk assessment for stroke! BP+ demonstrated accuracy for cBP to ARTERY requirements presented at #ESC2024 Suprasystolic Pulse Rate Variability (sPRV) has demonstrated high sensitivity AND specificity screening for #AFib vs 12-lead ECG, and importantly higher values shown to predict risk. sPRV should be added to risk scoring used to decide if anti-coagulation therapy is appropriate. @StrokeAHA_ASA

This updated guideline is intended to be a resource for clinicians to use to guide various prevention strategies for individuals with no history of stroke, and replaces the 2014 Guidelines for the Primary Prevention of Stroke.

There should be more information on screening for irregular rhythms and risk of stroke. @Uscom BP+ measures detailed pulse pressure rhythm waveforms and morphology not available on any other cuff based BP monitor. Every time you measure BP you get a risk assesment for stroke! BP+ demonstrated accuracyfor cBP to ARTERY requirements presented at #ESC2024 Suprasystolic Pulse Rate Variabilty (sPRV) has demonstrated high sensitivity AND specificity screening for #AFib vs 12-lead ECG, and importantly higher values shown to predict risk. sPRV should be added to risk scoring used to decide if anti-coagulation therapy is appropriate. @StrokeAHA_ASA

@nephronus I would suggest studies consider @Uscom BP+ to measure differences & change with intervention in peripheral pulse waves. Sensitive to changed vascular tone (endothelial function etc.) Help select best target patients for different HT agents.

New therapies for #hypertension #NephTwitter #MEDTwitter