Matt Cooperberg

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Matt Cooperberg

Matt Cooperberg

@dr_coops

Urologic oncology & epi, focus on #prostatecancer @UCSFcancer @UCSFurology. GU Chief @SFVAMC. All views strictly personal. RT≠E. #🟦

San Francisco, CA Katılım Eylül 2010
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Daniel E Spratt
Daniel E Spratt@DrSpratticus·
@dr_coops @DrewMoghanaki @alison_tree Agree Matt. We need 5-10 year data and ideally from RCTs before adopting a treatment in localized PCa. No one would ever think to adopt experimental tech without even RCT data with good followup right?
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Thomas Chi
Thomas Chi@thomaschi8·
My feet thank you millennials for making it cool to wear sneakers with a suit. Nothing like coming back from all day meetings at a 5 day conference and realizing your 🦶🦶don’t hurt! @dr_coops doing it in style!! @AmerUrological @UCSFUrology @UABUrology
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Benjamin J. Davies MD, MBA
Federal dollars fund a SWOG trial for the Tokyo BCG strain. Once P3 study is good we have a private company obtain the rights (ImmunityBio) for the BLA from JBL. Has there been any assurance that this public money will help the BCG crisis? Or is it just for ImmunityBio mid drug?
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Matt Cooperberg
Matt Cooperberg@dr_coops·
@daviesbj @KeithKow This is true for some massive % of drugs built on Federally funded science. Not saying NIH should take equity positions but taxpayers (Medicare/aid) should very reasonably get a (big) discount!
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Matt Cooperberg retweetledi
Ahmed Al-Khalidi
Ahmed Al-Khalidi@khalidi79397·
So why does "indigenous vs. colonizer" almost always mean Europeans, and almost never Bantu, Turks, Arabs, Slavs, or Han Chinese? A few reasons, in descending order of how much they actually explain: 1. Recency and documentation. European expansion happened in the era of the printing press, photography, census records, and treaties. The Bantu expansion left no paperwork. The Arab conquests are 1,300 years old and mythologized as religious destiny rather than conquest. When the receipts exist, the case is easier to make, and Europeans left receipts. 2. The winners wrote the framework. Modern human-rights language, postcolonial theory, and the very category of "indigenous peoples" were built in Western universities after WWII, primarily to process European guilt over European empires. The tool was designed for one job. Asking it to evaluate the Arab conquest of Egypt or the Turkic conquest of Anatolia is like asking a tax form to diagnose a disease. It wasn't built for that. 3. Christendom is critique-able; other civilizations aren't. You can write a bestseller attacking Western Christian civilization from inside a Western university and win awards for it. Try writing the equivalent book about Arab-Islamic conquest from inside Cairo or Istanbul. The asymmetry isn't about history. It's about which societies tolerate self-criticism and which punish it. So the critical literature piles up on one side and barely exists on the other. 4. The Soviet inheritance. Cold War-era anti-colonial framing was deliberately shaped by Moscow to delegitimize the West while giving its own empire and its allies' conquests, a pass. That framework outlived the USSR and still structures a lot of academic and activist vocabulary today. 5. Race makes it legible. European colonizers usually looked different from the colonized. Turkic conquerors of Anatolia, Arab conquerors of the Levant, and Bantu expansionists in Africa generally didn't look dramatically different from the populations they absorbed. The visual contrast made European empire easier to narrate as racial, and once a story has a clean visual, it travels. 6. And finally, Jews. The framework's selective application reaches its most absurd point when a people indigenous to a specific land, with continuous presence, language, religion, and archaeological record tying them to it for three thousand years, get labeled "colonial settlers", while the actual seventh-century conquerors who Arabized the region get labeled "indigenous." At that point the framework isn't describing reality. It's laundering a conclusion. The label isn't tracking who got there first. It's tracking who it's currently fashionable to blame.
Ahmed Al-Khalidi@khalidi79397

"Indigenous" is a real concept applied with a fake standard. The word means "the population already there when someone else arrived." Fine. The problem isn't the definition. It's that the people who deploy it loudest apply it to exactly one set of migrations and pretend the others never happened. The Bantu expansion swept across half of Africa, absorbing or displacing the peoples who lived there first. No one calls Bantu-speakers settlers. The Turks arrived in Anatolia in the 11th century and replaced Greeks and Armenians whose roots there ran thousands of years deeper. No one demands they go back to Central Asia. Slavs pushed into lands held by earlier Europeans. Arabs spread from a single peninsula across North Africa and the Levant, Arabizing populations that had been there since antiquity. Anglo-Saxons displaced Britons. Han Chinese absorbed countless earlier peoples across what is now southern and western China. None of these get the colonizer label. Each one is treated as just "history." The label only activates for a narrow, politically chosen set. Almost always Europeans, and almost always Jews returning to the one place on earth where their indigeneity is older than the word itself. That's not a definition. That's a filter. And the filter exists to produce a predetermined answer. Hate the messenger if you like. The history isn't an opinion.

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Matt Cooperberg
Matt Cooperberg@dr_coops·
@RomanCarvajal Nice summary - but where does 96% NPV come from? That’s far higher than most prior reports…
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DR CARVAJAL
DR CARVAJAL@RomanCarvajal·
At #AUA2026, the message was clear:
📌 ePLND provides staging information, but its therapeutic benefit remains uncertain.
📌 RCTs have not shown consistent improvements in BCR outcomes.
📌 PSMA PET/CT has a high NPV (~96%) and may safely avoid unnecessary PLND in intermediate-risk patients with negative scans.
📌 Morbidity is not negligible: lymphedema, DVT/PE, and potential overtreatment.
📌 Up to 47% of nodal metastases may even lie outside the standard ePLND template. The question is no longer “PLND yes or no?”
👉 It’s about smarter selection using PSMA PET, nomograms, and individualized risk assessment. #ProstateCancer #PSMAPET
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Alexander Kutikov MD
Alexander Kutikov MD@uretericbud·
Very impressive John K. Lattimer Lecture: Transurethral Robotic en-bloc TURBT- Challenging the Status Quo by @jteoh_hk #bladdercancer surgeons must take note. #aua26
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Matt Cooperberg
Matt Cooperberg@dr_coops·
Many congrats Jacob Taylor et al on @BJUIjournal paper of the year! #aua26 Long-term outcomes of bladder-sparing therapy vs radical cystectomy in BCG-unresponsive non-muscle-invasive bladder cancer
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Alastair Lamb
Alastair Lamb@LambAlastair·
This was quite distressing. Two #RARP in a row for GG1 #prostatecancer... Realise it's a technique session. But surely we can't ignore poor decision-making? Dr Kocher: "Good surgeon knows how to operate; excellent surgeon knows when (not) to operate" But the crowd want it! #AUA26
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