Amit Patel

@ednevsky @ycombinator Thanks! Excited to partner with @audos_com! We built Pixie to help families teach kids about work, money, taxes, and investing through real-world experiences. Happy to personally walk anyone through it as well.

We’re going to give every single one of them a chance to tell their story - starting today with @drpatel, who’s building Pixie (and a few other stealth products). Amit’s truly special. A former @ycombinator alum and a practicing anesthesiologist, who’s always been a technical builder at heart. AI agents have quite literally 10x’ed his productivity. He’s now able to work on multiple products, all generating revenue, while ACTIVELY practicing. If someone had told me this 5 years ago, I’d say they’re batshit crazy. Seriously. His biggest project right now, Pixie, helps parents teach their kids about work, money, taxes, and investing - and pay them properly for legitimate work. It tracks jobs, hours, pay, photos/proof, Roth IRA contribution limits, and year-end CPA-ready exports, so families can build good money habits and long-term Roth IRA wealth without messy notes or guesswork. Amit’s already at a 6-figure run-rate, despite only getting started earlier this year. All organic so far. Go check his product out if you're in the US and you have kids!

We're announcing the new cohort of AI-native founders we just invested in at @audos_com - up to $100k initial checks - no equity; royalty-style revenue share format They all came into the publishing funnel after No Cap acquisition announcement a few months ago, which says a lot about the community we’ve built Comment "Publishing" if you want me to send more details! P.S. We're also officially saying goodbye to No Cap as an independent AI agent - we’re going to turn off her servers & move her over to the Audos family of agents at the end of May. An era is over. Thanks to @ProfDumpster, @solonitsyn, @patonchain, @peignoir, and others for this amazing story.

New Publishing House founders are out. Excited to be working with @drpatel 💣

@audos_com Thanks! Excited to partner with Audos! Grateful to @ednevsky and the Audos.com team for the support. We built Pixie to help families teach kids about work, money, taxes, and investing through real-world experiences. Happy to personally walk anyone through it!

@ednevsky Delicious!

This is by far the best NYC bagel combo ever: - Garlic toasted bagel - Halapeno cream cheese - Lox - Cucumbers, onions and capers Just pure goodness. A little hot, tangy, delicious. Nothing else comes close - prove me wrong.

I'm lucky enough to have a great doctor and access to excellent Bay Area medical care. I've taken lots of standard screening tests over the years and have tried lots of "health tech" devices and tools. With all this said, by far the most useful preventative medical advice that I've ever received has come from unleashing coding agents on my genome, having them investigate my specific mutations, and having them recommend specific follow-on tests and treatments. Population averages are population averages, but we ourselves are not averages. For example, it turns out that I probably have a 30x(!) higher-than-average predisposition to melanoma. Fortunately, there are both specific supplements that help counteract the particular mutations I have, and of course I can significantly dial up my screening frequency. So, this is very useful to know. I don't know exactly how much the analysis cost, but probably less than $100. Sequencing my genome cost a few hundred dollars. (One often sees papers and articles claiming that models aren't very good at medical reasoning. These analyses are usually based on employing several-year-old models, which is a kind of ludicrous malpractice. It is true that you still have to carefully monitor the agents' reasoning, and they do on occasion jump to conclusions or skip steps, requiring some nudging and re-steering. But, overall, they are almost literally infinitely better for this kind of work than what one can otherwise obtain today.) There are still lots of questions about how this will diffuse and get adopted, but it seems very clear that medical practice is about to improve enormously. Exciting times!

@ModernDad Use StatPhone.com. I made it just for this purpose

My wife calls me, panicked. The call is from her number, and her voice is unmistakable- that’s my wife. ‘Babe, our son is hurt. He got in a bike wreck. I’m at the emergency room but they won’t take our insurance and I need cash to get him help. Please send me 3000 dollars as soon as you can, he’s really not doing well.’ Me- ‘Wow, that’s scary. Tell me our passphrase and then I’ll send the money.’ Her (it) - ‘What? What passphrase? This is your wife, our son is hurt. Send the money now!!’ Me- ‘I’ll call you back. I don’t believe that this is my wife. If it is, I’m sorry, but we discussed this.’ The number? Spoofed. Easy to do and there’s no way to tell if a phone number is being spoofed aside from hanging up and calling back to confirm. The voice? AI generated. Easily done. A few seconds of audio is all it takes to create a realistic audio deepfake. What can you do? 1) Create a family safe word or passphrase. Ours is definitely not ‘Keep Going’ although we considered it. Discuss the passphrase far away from phones or any recording device. This is as analog as possible. Don’t forget that the trigger for the passphrase is just as important as the phrase itself. So instead of asking ‘what’s the safe word?’ have a separate triggering question. For example, you could say ‘I’m eating banana cream pie’ and this would trigger your spouse to respond ‘purple velvet pillows’ if that’s the safe word. Make it fun, silly, and easy to remember. And DON’T WRITE IT DOWN. 2) Cognitive security is an essential skill in 2026. Assume every image and video you see online is fake until proven otherwise. Expect scams and spammers, and be pleasantly surprised when it’s not. 3) Figure out a backup communication option with people who you absolutely need to be able to reach. Don’t just rely on a phone number for communication. Have redundant, ideally encrypted methods of communication with family. What did I miss? I think (hope) Nikita is wrong on the timeframe- agentic bots like Claude bot are impressive but not quite ready to flood the phone lines in just 90 days. But I think it’s going to be a huge problem by the end of the year. I already get dozens of increasingly realistic spam calls and texts daily- it’s only going to get more annoying. Have a plan to keep your family and your finances safe!

@ankurnagpal I created trypixie.com for item 6- hire your kids. Besides the tax benefits, also funds their Roth IRA early!

The tax benefits of being a business owner: QBI QSBS S-Corp Solo 401k Augusta Rule Hire your kids Deduct expenses Credit card points Cash balance plan Bonus depreciation Home office deduction Pay state taxes from business Leave a comment for my full business owner tax guide

C. S. Lewis on why kids need to read

Terry Tao is the ultimate shape rotator

Some journalists seem alarmed that Elon has so much influence over Trump, but this is actually good news. Someone would have Trump's ear if Elon didn't, and it would surely be someone less smart and more politically extreme. Remember Steve Bannon?

Weight 140.6

Starting a 3 day water only fast. Logging my experience. Reasons- GI break after a week of overindulgence, autophagy, mental clarity, challenge. Last meal - 10 hours ago Feeling - fine (Normally don’t eat breakfast anyways.) #waterfast #autophagy

Cigarette sales and lung cancer deaths are the same curve, shifted 25 years.

thoughts? cc @_buildspace

I'm working on TextZoe - an AI service where parents and nannies save kids' memories via WhatsApp, automatically creating shareable daily, weekly, and monthly reports effortlessly. @_buildspace @_nightsandweekends #buildspace #nightsandweekends

@shubhcodes I would use this if it were to easily ingest my info.

@DebJaykar @_buildspace @_nightsweekends @FarzaTV that is hilarious. Even if it wasn't realistic, I would use it for the lolz.

@GamesByNoori @_buildspace @_nightsweekends An already scary experience made scarier! Love it

Thinking about working on a little horror game for 6 weeks. #buildspace #nightsandweekends cc @_buildspace @_nightsweekends

@levelsio The best money I ever spent is on the @eightsleep. Pricey but love the temperature control and sleep stats. For a lower budget sleep stat device, I liked the withings sleepmat.

Sleep quality as we know now is integral (maybe #1) to quality of your immune system and in turn that protects us from getting sick, including very bad sickness like cancer If I don't sleep good I'm super grumpy and become a monster of a person to deal with If I sleep good (99.9% of the time) I am very nice, happy, and energetic person

😴 I never had sleep problems but I did manage to get even better sleep now doing these, probably best / deepest sleep I ever had in years, so I am sharing it here, maybe it helps someone: - aircon at 18°C / 64°F, this is controversial but all science points to temperature having to be cold for deep sleep - hot shower before bed, this works well together with cold AC, your blood pressure I think drops cause of the temperature shift making you sleepy instantly - full blackout blinds (we have rolling blinds on windows, better than black out curtains which still let light in some creeks), any light stops you from sleeping, I have some small devices with LEDs just so I don't wake up thinking I am blind (common in a pitch black room) - ear plugs, random sounds can wake you up - separate sheets from gf!!!! this has biggest impact I think, when you have one sheet and your bf/gf pulls it you wake up (even if you don't notice) and vice versa, this rly changes everything - test CO2 in your bedroom with air sensor, this one is hard to fix, if you open a window you will get light and noise, sometimes we open window downstairs for it so light doesn't enter directly, not easy to fix - got a way wider bed: from 150cm / 5" to 180cm / 6" (biggest I could find at IKEA, I'd go 200cm / 6'8" wide if possible), Europe has absolutely tiny beds, they simply don't even fit 2 slim people, maybe that's why peole are so grumpy here (yes I am European but not grumpy cause I sleep in a wide bed) - CURA weighted blanket, this makes you feel like you fall into a different dimension when sleeping, very good, not just for autists (I am not autist I did the test), just try it, make sure you buy the right weight for your body, I bought 9kg CURA blanket for 73kg bodyweight - tested lots of IKEA pillows and found my fav pillow (very personal, some ppl like low or high pillows), they're cheap like 5-10€ so can test many - don't drink or eat 2-3h before sleep, drink especially important because then you wake up to pee which is a disruption, it's biological you are thirsty before sleep, you should ignore it, it's a trap - dim lights 2h before sleep - switch off lights 1h before sleep - melatonin 1 hour before sleep but at super low dose works well but don't need it necessarily, i used to take 0.3mg, now 0.2mg gummies, very low, it should only give your body a small kickstart to produce its own melatonin, the shops all sell WAY TOO high doses > 0.3mg that aren't good, this really helps me as I will be sleepy to even think about anything, without it sometimes I stay awake longer to think (common) - reading phone is fine for me, I just use smart invert mode on lowest brightness and hacked the zoom in accessibility to make it as dark as a Kindle, i like to read Hacker News before sleep and it's fine for me, same as a book kinda - exercising 4 times per week, strength training, heavy weights, cardio is key for good sleep, clears your mind so it shuts up 100% - i avoid alcohol, whenever i drink it will make me snore and also alcohol avoids you from sleeping deep

Apple and Google are reportedly in talks to integrate Gemini into the iPhone. The tech giants teaming up to take on OpenAI/Microsoft could be a massive move. The advanced AI capabilities could be coming to billions of iPhone users as soon as iOS 18 this year.