lena p

アメリカという国は、格差は激しいし薬物汚染はひどいし政治は(ご存知の通り)終わっているしで、どうしてあんな国が大国面して回っているのだろうと思っていたんだけど、最近タイムラインに10000件ほど流れてくるありえないサイズの肉塊の山の写真を見て、その物質的豊かさを急速に理解させられている

アメリカのニキたちが「オイオイ、JAPのヤツらホントはクソおもしれーじゃねェか─」と日本人のセンスに気付き始めてて草。こちとら英語は話せないけど、1000年以上前から短文で言葉遊びしてきてるンだわ。

a long time ago i had the experience of chatting irl with someone well known on twitter, well connected, well platformed, influential, etc. He was smart, seemed to have domain expertise in his technical field. But gradually over the course of the conversation I realized he didn't actually know what he was talking about. He used complicated words, but in subtly off ways, and would reply to questions with things that sounded like answers but actually weren't.He'd confidently reference concepts that I think he assumed I didn't know, but I did know, and I knew that the term he used didn't actually have anything to do with his claim, etc. But his confidence was intense and radiating, and the speed at which he talked and the complex vocabulary he used really disguised what I perceived to be both a lack of deep understanding of the material and also a lack of self-awareness that he didn't have deep understanding! I've def met people who disagree with me online who I think *do* engage deeply with the concepts, but this specific one didn't, and it was a little blackpilling for me to realize that he had such a following from a bunch of people who couldn't tell the difference.

A 2025 Nature study revealed a surprisingly simple way aspirin might help fight cancer metastasis. Researchers discovered that cancer cells trick blood vessels into releasing a substance called thromboxane A2 (TXA2). This chemical then sends a signal that basically tells our immune system’s T-cells to “stand down,” making it easier for cancer to spread. Science nugget: In mouse models of breast, skin, and bowel cancer, aspirin blocked TXA2 production. This freed up the T-cells to attack more effectively, resulting in significantly fewer metastases. When scientists genetically removed the key protein (ARHGEF1) that receives the signal, metastasis dropped sharply — and aspirin had no extra effect, proving this is the main pathway. The study helps explain why some earlier human observational data showed potential protective effects (especially for colorectal cancer). However, these promising results are still from mice, and experts stress that we need proper clinical trials in humans to confirm who might benefit and what the risks are. Any use of aspirin for cancer-related reasons should only happen after talking to your doctor, due to side effects like increased bleeding risk. It’s a fascinating reminder that an old, cheap drug might still have hidden powers we’re only beginning to understand. Does this aspirin-cancer connection surprise you, or does it make you curious about what other everyday medicines might have undiscovered effects?