hyper(bolic) disco(unting) girl

@FagiWyt13275 @ErinMondays @bowtiedwhitebat @WestsideLAGuy he didn't want kids with her

@ErinMondays @bowtiedwhitebat @WestsideLAGuy And this is all that matters, none of that "love" was enough for her. Its all cope

This is successful founder of Airtable Howie Liu & wife (she’s 3 years older). They have a great life together, new baby, and I’m sure he’s a loyal provider husband & dad. But she’s not genuinely sexually & romantically attracted to him. To deny this reality is cope.

@Enlibriated @D4RW1NEXE @bryan_johnson Lmao

@D4RW1NEXE @bryan_johnson Elite ball knowledge

Two doses of magic mushrooms degraded my sperm count from the 99.6th percentile to the 77.7th. This may be a first-in-human observation. Context: we ran the most quantified magic mushroom (psilocybin) experiment ever conducted. We were asking if psilocybin is a longevity therapy. After seeing the data, we think it is (see reply post for the experiment summary). Also, like most things biology: the results are complicated. My data suggests that the magic mushrooms (psilocybin) negatively impacted my fertility markers. Before the first psilocybin dose my motile sperm count was at 99.6th percentile for men under 25 years of age, it dropped to 77.7% and partially recovered to 89.3% following the first dose, and second doses, compared to the same age cohort (numbers compare similarly to my age cohort as well). 3 days following my second dose (first dose 25 mg, second dose 28 mg) . Motility: dropped 51% . Total count: almost unchanged, dropped by 2% . Total motile count: dropped 52% . Normal morphology: dropped by 50% 20 days post 2nd dose, the pattern continued, with typical latent effects on total sperm counts Motility: recovered back to -2% of pre-psilocybin baseline: . Total count: dropped by 38%, latent effect. . Total motile count: remained inhibited at -39% of pre-psilocybin baseline, (despite motility normalizing, due to the total count drop) . Morphology normalized to -10% of baseline levels. Reduction in free testosterone might have contributed to the effect. While total serum testosterone increased by 30% 3 days following the 2nd dose (neither FSH or LH were meaningfully affected either), and continued to be at 11% above baseline, SHBG increased by 37%, SHBG binds testosterone and reduces its bioavailability and activity. My free testosterone (direct) showed 24% and 23% drops at 3 and 20 days post 2nd dose. In light of the neuroplastic, well-being, brain reset, and systemic metabolic and anti-inflammatory benefits, the trade-off is probably worth it. Especially considering that the magnitude of inhibition has no meaningful effect on actual fertility (total motile counts above 50 million are still on the safe side). This is a first-in-human observation, to our knowledge there is no published human clinical study demonstrating that psilocybin diminishes male fertility markers. General mechanistic evidence exists for recreational and psychoactive drugs possibly inhibiting fertility markers due to their effects on the hypothalamus-pituitary-adrenal axis and general hormonal reset.  Yet no direct evidence for psilocybin or other similar psychedelics inhibiting fertility markers exist. A potential mechanism for the immediate inhibition of motility could involve direct serotonergic signaling in sperm. Human sperm express multiple serotonin receptors, including 5-HT2A, and one recent study found that a 5-HT2A antagonist reduced sperm motility, suggesting that 5-HT2A may regulate motility. Psilocybin is known to bind 5-HT2A with high affinity.

@etirabys damn this ad feels intimate

facebook marketplace is really insistent about showing me this one even though it KNOWS I mostly want mulch and children's books

@dundereloise Would you recommend the experience

I'm cheap so I thought I'd never go to a Michelin star restaurant, but yesterday I got to go for free. One of their courses features plankton. Yes the little floaty things that live in the ocean. Yet another win for my horseshoe theory of dining. I could imagine some destitute fisherman settling for plankton on days he doesn't manage to catch a fish.

@pammalamma Disclaimer I hang out in my bathroom habitually cuz it's warmer than the rest of the house but i have no issue with the hard floor idk

@hyperdiscogirl I…

fun fact about me i can sleep anywhere, i frequently fall asleep on the floor and a few days ago i slept the whole night on the bathroom floor with a robe for a blanket

@meadandjuniper Just Do it

@hyperdiscogirl …how

@cameronspirals oh lol why

@hyperdiscogirl girl you might have sleep apnea

@tunient i feel like if I clicked on the blue link i would find some sort of misinfo tiktok rabbit hole

@hyperdiscogirl i wonder what the commentator meant by this. afaict it is maybe harder to investigate crimes on cruises but idk if it's true x.com/tunient/status…

saw this comment earlier and can't stop thinking about it

@RogeFather @VERYKOOLLUKEY Those can actually survive digestion and reach the intestines in meaningful amounts!

@hyperdiscogirl @VERYKOOLLUKEY Cool, and is this the same way that prebiotics and prebiotics work...?

Pasteurized milk is a processed food I used to think raw milk was simply about being more nutritious, which is certainly true I have come to realize that the enzymes are even more important Lactase, lactoferrin, amylase, catalase, ect… all destroyed by pasteurization These enzymes are essential in metabolizing the milk and important for overall health Here are some of the enzymes in milk and there properties: - Catalase: Acts as an antioxidant, breaking down hydrogen peroxide into water and oxygen to prevent oxidative stress within the milk - Amylase: Assists in the breakdown of starch into sugars - Lactoferrin: immune system boosting, designed to protect the nursing young from infection, protects you from getting sick from any contaminants in the milk - Lactoperoxidase: one of the most abundant enzymes, anti-microbial, inhibits the growth of a wide range of bacteria, including Salmonella and Staphylococcus aureus - Lipase: essential for lipid metabolism, responsible for the hydrolysis of milk fats into free fatty acids and glycerol These enzymes prove that milk should be raw, the way God intended Lactase is the same enzyme they give lactose intolerant people, found in REAL milk Other enzymes literally prevent any kind of pestilence the milk could have Milk is perfect the way it is

@RogeFather @VERYKOOLLUKEY No, they're not. However, if you didn't, the quantities of enzymes in raw milk aren't going to make up for it, because 1) the quantities are comparatively small 2) most of that will get denatured by your stomach acid before it ends up in the intestines

@hyperdiscogirl @VERYKOOLLUKEY Gut microbiome balance is important. Saying that you have "all the enzymes" is a statement that needs a bit more clarification. You're 100% certain that the ratios are all perfect in all people?

My friend Kevin told me about this page of Unparalleled Misalignments by Ricki Heicklen and it will be one of those web pages I turn to for years and years and just chuckle with deep pleasure. TED Talk —> Edward Said is just 🤌🏼 rickiheicklen.com/unparalleled-m…

@DanielleFong grillchee

never kill yourself

@dioscuri u looks the same

Scrolling back to 2011 and every single photo looks like it was taken inside a glass of sepia-tinged orange juice.

@abjectbaby the diff experresion also... cheeks look way more full when smiling

Buccal fat removal is when you use bronzer and the camera is angled down

@powcampsurvivor sounds like you get it pretty well

i really dont get sabrina carpenters thing. the aesthetic is like shes a sexy cartoon mouse who acts like a prostitute and also a baby. all of the songs are about how she needs to get stuffed by some oaf and they all sound like say so by doja cat but 70% worse

@sandwichlover7 (fake body) (fake situation)

that’s not true