John M Suffredini

Finally, a sham-controlled CTO PCI trial—and it delivers. ORBITA-CTO: small (n=50), but rigor where it matters—blinding, placebo control, symptom-level data. CTO PCI improves angina beyond placebo, with a clear reduction in episodes and more angina-free days. Not prognosis, not hard endpoints, but real symptom benefit—properly measured. #acc26 jacc.org/doi/10.1016/j.…

Presented at #ACC26: Among patients with atherosclerotic cardiovascular disease, targeting an LDL cholesterol level below 55 mg per deciliter led to a lower 3-year risk of cardiovascular events than targeting a level below 70 mg per deciliter. Full Ez-PAVE trial results: nejm.org/doi/full/10.10… Editorial: Paving the Road toward Targeted Lipid Lowering nejm.org/doi/full/10.10… @ACCinTouch

In diabetic patients with LM & TVD, #PCI was associated with ⬆️3yr risk for death, non-fatal MI & stroke (17.0% vs 12.4%; HR: 1.91; 95% CI: 1.50-2.44; P < 0.001). However, risk for the primary outcome was comparable between IVI-guided PCI & #CABG. jacc.org/doi/10.1016/j.… #JACCINT

2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/ SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults ahajrnls.org/3MzH1ha

It's an honor to be entrusted by @NASA to conduct our fifth commercial human spaceflight mission onboard the @Space_Station. Axiom Space has sent 14 astronauts, representing 11 nations to the station in the past 4 years, with crews conducting 160+ research and 100+ outreach activities. We are #BuildingOpportunity for countries around the world to access microgravity for discovery and inspire others to #TranscendEarth. None of this would be possible without the trust of our customers, partners and the hard work of #TeamAxiom. Read more: axiom.space/release/ax5-aw…

Thrilled to welcome our newest fellows to the BCM Cardiovascular Disease Fellowship! We’re so proud to have you join our family and can’t wait to work together to advance education, research, and patient care. @BCMHeart #BCMFellowship #Cardiology #FutureLeaders #ACCFIT

Patent foramen ovale (PFO) is present in approximately 25% of all adults and is a common cause of stroke in young and middle-aged patients. 📝 This Review discusses PFO-associated stroke management. ja.ma/430lxyZ

So lucky to be part of the @BCMHeart FIT jeopardy team. We went from Wild Card to 2nd place in the state (almost won) but grateful to learn and have fun! Great meeting by @KTamirisaMD & @txchapteracc! Thnx to @Umair2017 @john_suffredini @wilzawall #ACCFIT #ACC #CardioX

Sub-analysis of the BEST trial showing IVUS-guided PCI equivalent to CABG! An excellent review of the paper by @GreggWStone discussed how we can be better at what we do and be equivalent to bypass. In the order of importance, just in my opinion! 1-Intravscular imaging. A must, not an option. Needs meaningful use not just "use" 2-Complete revascularization- I am a huge believer. Complete the job 3-Physiology! will leave it to physiology enthusiasts :D heart.bmj.com/content/111/19… heart.bmj.com/content/111/19… #cardioX

Provocative study from the RENOVATE trialists and Samsung Med Cntr suggesting use of intravascular imaging may eliminate long-term diffs between CABG & PCI. Not definitive absent a powered RCT, but should be enough to mandate IVI in these pts, esp with class I guidelines. Agree?

The Axiom-4 mission will do solid science and help prep for a replacement for the International Space Station ti.me/4dU8T8X

Coronary Angiography After Out-of-Hospital Cardiac Arrest Without ST-Segment ElevationOne-Year Outcomes of a Randomized Clinical Trial: @JAMACardio 🥸TOMAHAWK - and out of hospital cardiac arrest without STEMI 😱Here you go 👇👇👇👇

10-Year Outcome of Complete or Infarct–Artery-Only Revascularization in STEMI with Multivessel Disease (DANAMI-3-PRIMULTI): @JACCJournals 🥸 FFR-guided complete revascularization - 10 year outcomes 😱 Summary 👇👇👇

Welcome to the incoming BCM Cardiology fellowdhip class for 2025!! So excited to have you join the BCM family!!

ECLIPSE trial showed orbital atherectomy no different from conventional balloon angioplasty for preparation of severely calcified coronary lesions prior to DES implant #TCT2024 View interview here: clinicaltrialresults.org/wp-content/upl…

New post hoc analysis from the ISCHEMIA trial: Revascularization (PCI or CABG) in 3-vessel CAD patients lowers 4-year rates of cardiovascular death or MI and improves quality of life, but shows no clear impact on overall mortality compared to conservative management. #EAPCI #interventionalcardiology #ischemiatrial ow.ly/QnFr50TRMoe

"Our elite teams have redefined spacesuit development, establishing new pathways to innovative solutions and applying a state-of-the-art design approach for the #AxEMU,” said Matt Ondler, Axiom Space President. @Prada #IAC2024 axiomspace.com/release/prada-…

In the NOTION-3 trial of percutaneous coronary intervention or conservative treatment in patients undergoing TAVI, PCI was associated with a lower risk of a composite of death, MI, or urgent revascularization at a median of 2 years. Full results: nej.md/3AH5WJo #ESCardio

Thrilled to collaborate on this paper on "Early Onset Athero..." with a stellar group led by Idine Mousavi and @jia_xiaoming and co! 🌟This review and our proposed #cvPrev strategies out now in @ESC_Journals 👇 doi.org/10.1093/eurjpc… @ErinMichos @CBallantyneMD @virani_md

Impact of Elevated Gradients After Transcatheter Aortic Valve Implantation for Degenerated Surgical Aortic Valve Bioprostheses ahajournals.org/doi/10.1161/CI… Special thanks to @RYKherallah and all others for bringing this project over the finish line!