Lexi Rovner

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Lexi Rovner

Lexi Rovner

@lexrovner

co-founder & ceo @64xbio | @ycombinator S18 | prev @ucberkeley, @yale, @geochurch lab, @wyssinstitute, @harvard | musician, runner, skier

San Francisco, CA Katılım Ekim 2012
2.1K Takip Edilen2.8K Takipçiler
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Lexi Rovner
Lexi Rovner@lexrovner·
We’re launching LV Apex Suite today, our second Apex Suite after AAV. Each new modality adds data on what’s shared, what’s different, and how to engineer production systems in an integrated way. That’s tied to a core view at @64xbio: Cell lines, reagents, and process aren't separate levers, they're interdependent parts of a single production system. If we want better productivity, quality, and scalability, we need to understand and engineer that system more holistically. That’s what we’re building toward with CellMap: data-rich experimental maps of production biology that we can learn from computationally, to guide the design of better cell lines and reagents. Biologics are next, and existing suites will keep expanding with additional tools. With this, we’re also growing our commercial and ops teams. If you’re excited about building next gen biomanufacturing tools, DM me. Incredibly proud of the team today for all the work behind this launch. Much more to come.
64x Bio@64xbio

New product launch: Today we’re launching LV Apex Suite, a new product suite for lentiviral vector production. This marks 64x Bio’s expansion from AAV into LV — and another step in translating our CellMap-driven VectorSelect platform across new modalities. LV Apex Suite begins with a high yield engineered HEK293T suspension cell line for transient LV production, with stable systems and additional production-enabling technologies in development. More broadly, this launch reflects where 64x Bio is headed: expanding CellMap as a data foundation for production biology, and learning from those data computationally to iteratively guide development of better cell lines, reagents, and production systems for viral vectors — and soon, biologics. To learn more about LV Apex Suite, read our press release below and visit 64xbio.com/lvapexsuite. Press release: 64xbio.com/articles/64x-b…

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Nima Alidoust
Nima Alidoust@nalidoust·
Today we are introducing Tara. Biological datasets are a source of insights and a means to train biological AI models. As the ability to reason at scale emerges, they take on a new role: the ground truth for testing what reasoning models produce, and the environment in which those models operate, get feedback, and improve. Tara, our autonomous research agent, is embedded in our ever-expanding datasets, lab-generated and synthetic, and built to test and evolve the hypotheses frontier models generate, matching the pace at which they produce new ideas. By keeping those models grounded in a vast space of high-precision biological data, we believe we can compound biological reasoning and close the impedance mismatch between hypothesis generation and validation.
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64x Bio
64x Bio@64xbio·
Thanks @PharmaMfg for covering our LV Apex Suite launch! To read more about our new product launch, read our press release here: 64xbio.com/articles/64x-b…
Pharma Manufacturing@PharmaMfg

#64xBio adds #cellengineering platform to #lentiviralvector manufacturing. The new product suite extends the company's vector production platform beyond #AdenoAssociatedVirus applications to support #lentiviral therapies. pharmamanufacturing.com/industry-news/… #AAVs #viralvectors #biologics

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Lexi Rovner
Lexi Rovner@lexrovner·
We’re launching LV Apex Suite today, our second Apex Suite after AAV. Each new modality adds data on what’s shared, what’s different, and how to engineer production systems in an integrated way. That’s tied to a core view at @64xbio: Cell lines, reagents, and process aren't separate levers, they're interdependent parts of a single production system. If we want better productivity, quality, and scalability, we need to understand and engineer that system more holistically. That’s what we’re building toward with CellMap: data-rich experimental maps of production biology that we can learn from computationally, to guide the design of better cell lines and reagents. Biologics are next, and existing suites will keep expanding with additional tools. With this, we’re also growing our commercial and ops teams. If you’re excited about building next gen biomanufacturing tools, DM me. Incredibly proud of the team today for all the work behind this launch. Much more to come.
64x Bio@64xbio

New product launch: Today we’re launching LV Apex Suite, a new product suite for lentiviral vector production. This marks 64x Bio’s expansion from AAV into LV — and another step in translating our CellMap-driven VectorSelect platform across new modalities. LV Apex Suite begins with a high yield engineered HEK293T suspension cell line for transient LV production, with stable systems and additional production-enabling technologies in development. More broadly, this launch reflects where 64x Bio is headed: expanding CellMap as a data foundation for production biology, and learning from those data computationally to iteratively guide development of better cell lines, reagents, and production systems for viral vectors — and soon, biologics. To learn more about LV Apex Suite, read our press release below and visit 64xbio.com/lvapexsuite. Press release: 64xbio.com/articles/64x-b…

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Lexi Rovner
Lexi Rovner@lexrovner·
Headed to #BIO2026 next week. Lots of exciting things happening at @64xbio right now and we’re also expanding our commercial and ops teams. DM me to meet up, I’m excited to see everyone there.
64x Bio@64xbio

We'll be in San Diego next week for #BIO2026! The 64x team will be on the ground and @lexrovner is on two panels on advanced medicines, across AI and manufacturing. If you'll be there, we'd love to meet — reach out to us in the BIO partnering portal or at bd@64xbio.com

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Midjourney
Midjourney@midjourney·
Announcing a new division of Midjourney called "Midjourney Medical"
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SpaceX
SpaceX@SpaceX·
SpaceX has exercised the option to acquire @cursor_ai in an all-stock transaction with the goal of building the world’s most useful AI models. For the past few months, SpaceXAI has been jointly training a model with Cursor, which will be released in Cursor and Grok Build soon. We look forward to working closely with the Cursor team to advance our frontier AI capabilities
SpaceX@SpaceX

SpaceXAI and @cursor_ai are now working closely together to create the world’s best coding and knowledge work AI. The combination of Cursor’s leading product and distribution to expert software engineers with SpaceX’s million H100 equivalent Colossus training supercomputer will allow us to build the world’s most useful models. Cursor has also given SpaceX the right to acquire Cursor later this year for $60 billion or pay $10 billion for our work together.

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Gleb Kuznetsov
Gleb Kuznetsov@glebkuz·
Last week, I was invited to present at @AnthropicAI'e Boston Tech Week event. Since the Claude Code moment at the end of last year, the way we do science at @ManifoldBio made a quantum leap overnight. But really, it just came full circle. Manifold was founded by “hybrid scientists” and most of our first few hires could and did both code and do wet lab experiments. This was critical to invent and build the foundational molecular barcoding tech that lets us do the million-scale experiments no one else in the world can do, including interrogating drug candidates directly in vivo. Soon, the form of most of the data generated at Manifold became next-gen DNA sequencing data. (At the Anthropic forum, I live vibe-analyzed a summary that showed we’ve now done 525 NGS runs generating over 70 tera-bases — 10,000 human genomes worth). Engineering biology through this NGS lens is both a feature and a challenge. A feature, because this is how Manifold unlocks massive parallelism (a.k.a. GPU-ification of biology). A challenge, because for many scientists this was the first time they couldn’t easily analyze their own data, and became bottlenecked by a dedicated computational counterpart to help turn around insights, which still took weeks. Over night, that bottleneck has evaporated, aided by a strong data integration layer and an agentic interface we’ve built on top. Once again, everyone at Manifold Bio has become a hybrid scientist, just in time as the in vivo engine has achieved both scale and richness that have not been possible before. Even before this, we had already started making immensely valuable discoveries, including shuttles exploiting novel portals to deliver medicines to the brain – a high value problem that led to our first landmark deal with Roche last fall. Now that the loop is closed for scientists (and agents) at Manifold Bio, the pace of these discoveries is accelerating and we’re about to sweep through many more of the grand challenges in medicine. Thanks again to the Anthropic team for the opportunity.
Manifold Bio@ManifoldBio

Last week, @Anthropic brought together a select group of founders for their Founders’ Lab during #BOSTechWeek. Super to have our Co-Founder & CEO, @glebkuz , be selected to share how @ManifoldBio is doing science in the new era of agents!

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NewLimit
NewLimit@newlimit·
Following breakthrough results, we’re bringing longevity medicine to human trials. We’ve raised a $435M Series C led by @foundersfund to make it happen. Reprogramming cell age has the potential to create more healthy years for everyone. We're closer than ever to realizing it.
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Seth Bannon
Seth Bannon@sethbannon·
Can't we do better? First short film from @fiftyyears.
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Sam Rodriques
Sam Rodriques@SGRodriques·
We live in a golden age of biology. So why are people still dying from disease? Because discovery and development move slower than they should. Today, we’re partnering with Incyte to change that. Kosmos is now the first agent that can compress months of drug development into weeks, from the earliest stages of scientific discovery through to FDA approval. @Incyte will be the first company to deploy it across their pipeline. Work that used to take a team of scientists months now happens in weeks. Patients can't wait, and neither can we.
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Jared Friedman
Jared Friedman@snowmaker·
"Make something agents want"
Y Combinator@ycombinator

Software for Agents @aaron_epstein The next trillion users on the internet won't be people. They'll be AI agents, and they're already doing real work on top of software that was designed for humans clicking buttons. Every major category of software needs to be rebuilt for agents as first-class citizens, and that won't come from incumbents.

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Demis Hassabis
Demis Hassabis@demishassabis·
I’ve always believed the No.1 application of AI should be to improve human health. That work started with AlphaFold, and now at @IsomorphicLabs with the mission to reimagine drug discovery and one day solve all disease! We are turbocharging that goal with $2.1B in new funding.
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Josh Kopelman
Josh Kopelman@joshk·
Beginnings Matter. Who you are is a reflection of how you were raised. I am a reflection of how my parents raised me. And all of the founders I’ve been privileged to work with are a reflection of how they were molded by their parents. On Mother’s Day, @firstround thought we’d give some of our founders the opportunity to acknowledge the impact their mom had on them. @martabralic’s mom came to the US from Serbia without knowing anyone, learned English and programming languages to pick up new jobs to support the family. She gave Marta the confidence that she, too, could do hard things, like building @pomelocare. @kareemamin's mom modeled grace under pressure (even when Kareem once crashed her car). That’s probably why Kareem has an insane ability to remain calm under pressure, which he uses every day at @clay. @celinehalioua's mom pursued her PhD and instilled a love of research in Celine, which inspired her to start @loyalfordogs. Happy Mother's Day!
Liz Wessel@lizwessel

Beginnings Matter.  Behind so many founders are the moms who first shaped them. Happy Mother’s Day.

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