Narod Daldal

We are accepting applications. If you are passionate about research or want to become an expert in an area of Computer Science check out the list of projects offered this year in #AI, #CyberSecurity , #QuantumComputing, #HCI, Bioinformatics and many more. ucd.ie/cs/phdvacancie…

we are looking to recruit a PhD student to use systems / integrative approaches to understand the role of paralogs in disease. full details here: cancerdata.ucd.ie/vacancies/

Thrilled to present multilocus pathogenic variation contributing to intrafamilial clinical phenotypic heterogeneity in NDDs with our visiting scholar Tugce Bozkurt-Yozgatli @btugce__ as the first author bmcmedgenomics.biomedcentral.com/articles/10.11… @LupskiLab @GREGoR_research @UTHealthSPH

Excited to share our recent work published in @MedCellPress, the very first systematic review and analysis on synthetic lethality in oncology, led by Alejandro Schäffer, @ChungYoungmin, @AKammula and @joo_sang_lee. Buckle up! 🚀 cell.com/med/fulltext/S…

UCD School of Computer Science (@UCDCompSci) PhD scholarships with a deadline of 5th February 2024. Consider applying! I'll have a project on the identification of therapeutic targets in cancer, involving a collaboration with @GOLDLab_UCD ucd.ie/cs/phdvacancie…

perspective piece in @NatureGenet with Lovely Paul Solomon Devakumar @stveep and @IcrLordLab. Thinking of synthetic lethality in cancer as a two-gene phenomenon is limiting. Environmental & other genetic factors are likely to play a significant role rdcu.be/dsrzs

Delighted that our paper is now out in NAR Cancer! Making use of CRISPR screens @CancerDepMap we systematically evaluated the ability of gene regulatory networks (GRNs) to identify genetic dependencies in cancer! A short thread on what we found 🧵1/9 academic.oup.com/narcancer/arti…

delighted to see @dekegelb's work out in @MolSystBiol! Tumors tolerate astonishing numbers of genetic alterations, including homozygous deletion of entire protein coding genes. How? Here we explored one potential explanation – paralog dispensability! embopress.org/doi/full/10.15…

@pinar_altinerr @emel_timucin Congrats 🎉

I'm delighted to announce that my master's project - Computational completion of the Aurora interaction region of N-Myc in the Aurora a kinase complex- was published. I would like to specially thank my supervisor @emel_timucin for her support. #compbio pubmed.ncbi.nlm.nih.gov/37884585/

Fantastic opportunity for a fully funded 4 year #genomics PhD position @TheCancerGenome @RCSI_Research. Informal enquiries can be directed to simonfurney@rcsi.ie Applications can be made at: forms.office.com/e/XdzYK6cD09 Application Deadline: November 19th 2023

Glad to see that our paper is now out @LSAjournal ! In this work, we analysed how antibody reliability influences the correlation between mRNA and protein abundances for proteins profiled using Reverse Phase Protein Arrays (RPPA) life-science-alliance.org/content/6/8/e2…

New paper with @idmehta @naar_k @David_J_Adams in @trendscancer. We review methods for identifying synthetic lethal interactions between paralogs in cancer and discuss some of the challenges of exploiting them for the development of targeted therapeutics sciencedirect.com/science/articl…

Gene regulatory networks (GRNs) are used to identify vulnerabilities in cancer, but it's unclear how good they are at this. Here, we used CRISPR screens to systematically evaluate the ability of GRNs to identify genetic dependencies in cancer. biorxiv.org/content/10.110… Thread: 1/16

@Shehata92 @PCCP @emel79383901 @aise_unlu @silviaosu Congrats! 🎉

Third paper from my PhD thesis is out today in @PCCP I am very grateful to @emel79383901 for her great work on this and to @aise_unlu for being there when experiments needed Thanks @silviaosu and Javi for your guidance and for hosting me in your lab! tinyurl.com/yufpnvwj

@SaintZainn and I shared our experiences organizing @ICBG2022 symposium in the @sysbioire blog. The post is here: bit.ly/3W1Ir3U 🔵 Registration for the symposium will close on October 31st! Don't forget to register and submit your abstracts!

@eraysahin89 Thank you! ☺️

@naar_k Congratulations 🎉

I’m delighted to present my research at the #conwayfest22 and receive commendation from my review panel. This big smile is for all who took an interest in my project and offered their words of praise. It was amazing to exhibit my project next to all the other incredible studies!

@sharmarashmi343 @colmr @AnjanVenkatesh @UCD_Conway @UCDCompSci @GenomicsCRT Thank you Rashmi! ☺️

@colmr @naar_k @AnjanVenkatesh @UCD_Conway @UCDCompSci @GenomicsCRT Congratulations @AnjanVenkatesh , @naar_k and to the team!

Woop woop! Congrats to @naar_k and @AnjanVenkatesh who both had commended posters @UCD_Conway #conwayfest22 cc @UCDCompSci @GenomicsCRT

Why is the density of neutral mutations critical to train protein stability predictors? Find out the answer in my recently published master's thesis: pubs.acs.org/doi/10.1021/ac… #AcademicTwitter

🗣️📢 NEW ONLINE EDUCATION PROJECT I'm thrilled to announce Biological Modeling, a new online course. * Free and always will be! * Fun and wacky stories! * Dozens of software tutorials! * Want to preorder the book? Kickstarter below!👇 Check it out at biologicalmodeling.org.