Daniel

@sanilrege curious what the magical thinking approach is to these findings? onlinelibrary.wiley.com/doi/full/10.10…

@AlanCarson15 how best to downplay these findings? onlinelibrary.wiley.com/doi/full/10.10…

@alexandrer81988 @tabler_tim @MECFSSD @loscharlos Okay thanks a lot for the information i didnt know about andorra. I am sick 10 + years now and hoping something comes that can make a big difference. LDN helps a little but. I use methylene bkue too. But no major improvements sadly.

@opus__33 @tabler_tim @MECFSSD @loscharlos Yes I have a spectro mri showing a lot of inflammation and acetate for me in brain I don’t know if I am lc or me cfs. I had nothing before covid infection. Andorra it is real pharmacies and they sell you what you want and you are sure of the drug quality.

Advanced brain imaging shows widespread white-matter neuroinflammation in ME/CFS, with tissue swelling, immune cell infiltration & nerve fiber reorganization across key brain pathways correlated with greater disability, even when standard MRIs look normal. onlinelibrary.wiley.com/doi/full/10.10…

@alexandrer81988 @tabler_tim @MECFSSD @loscharlos Im actually MECFS but with it affecting cognition mainly. Neuroinflammation seems to be a key driver for me. Im in ireland, was thinking about using indiamart. What is it about andorra?

@opus__33 @tabler_tim @MECFSSD @loscharlos I am sorry for you lc is not degenerative so less serious than SLA but the level of disability and utter pain how people are left for dead with no rights and no ability to study and work is very sad people just don’t know the years people go through. Are you in Europe ? Andorra

@tabler_tim @alexandrer81988 @MECFSSD @loscharlos im considering baricitinib too. My cognitive problems are very severe but getting my hands on it is another matter.

@alexandrer81988 @MECFSSD @loscharlos Oh that’s interesting. What have you noticed with baricitinib?

@DrMichaelScoma Immune modulation approach to treatment?

The clinical signature is unmistakable and often written off as neuropsychiatric illness: 🔹extreme light sensitivity 🔹sound intolerance 🔹overwhelming sensory overload Disrupted cortical and thalamic networks impair the brain’s ability to filter and process incoming stimuli.

The “Brain on Fire” Hypothesis “My brain feels inflamed.” My patients report this constantly. Persistent neuroinflammation drives sensory disruption and cognitive impairment with autonomic dysfunction as a driver. Conventional testing - and thinking - often misses the mark.

@mecfsskeptic I understood Jarred Youngers research indicated significant neuroinflammation as demonstrated through PET and MRS.

9) Link to the paper: Omdal et al. 2026. Long-COVID: assessment of circulating markers suggests no cerebral neuronal damage, neuroinflammation or systemic inflammation-a controlled study. nature.com/articles/s4159…

1) "The absence of neuroinflammation markers is consistent with the hypothesis that persistent long-COVID symptoms are unlikely due to ongoing neuronal injury or central nervous system inflammation" From a Norwegian study that tested 48 LC patients.

@cstroeckw Does younger's microglia activation study change the narrative at all?

I think one of the many reasons ME/CFS has been shunned is because medicine, especially in its more clinical form, still often equates “no classical inflammation” with “no disease.” The core pathology probably is downstream of oxidative stress resulting in dysfunction/damage invisible to the inflammation-based diagnostics.

@Gmwetz I had pain relief in short term but wasn't a good solution over a number of days and don't use at all anymore.

I had the worst brain issues since my start of #LongCovid two years ago. Yesterday I took IBUPROFEN 600 and my brain issues are better today. Anyone else have the same experience?

@Karl_Lauterbach Thank you for your support

Frau Bonk hat ME/CFS seit sie an COVID erkrankte. Sie lebt auf dem Land in MV, ihr Leben ist sehr schwer. Habe ihr von den laufenden Studien berichtet, aber es wird Jahre dauern, bis wir eine echte Therapie haben. So lange müssen wir ihr Leben erleichtern. Wir geben Niemanden auf

@profmsharpe @findboundary @GeorgeMonbiot @ThosVarley However, I hope the point I am trying to make is clear which is the psychological effects of ME/CFS are downstream from the organic illness. I would also like to note that one need not make the final decision regarding funding or direction of research to effect these decisions

It’s the greatest medical scandal of the 21st Century. Intransigent doctors and gullible journalists have made the lives of ME/CFS patients a living hell. A massive and shocking story in this week’s column. theguardian.com/commentisfree/…

@muiris30 @RichardHanania So what is your reasoning for immigration that is occurring in the tech industry for example. Or in engineering fields or scientific research? Are u saying foreign workers in these fields is not needed even if they have skills and talent to contribute?

I think the best minds on the “dissident right” realize economic nationalism is just a less honest form of racialism. “Markets and trade are good except when with foreigners, then you become poor!” The “economic” arguments against immigration and trade are laughable, a fig leaf

@InvertTheWing Maybe be a slightly hyperbolic statement on your part, but he did look a serious addition with his pace and goal threat

Absolutely huge. His fitness was the difference between Tottenham winning and losing this weekend.

@bonchieredstate Whatever u think about his debating it is just a fact that he is a bad campaigner

@mattwhitlock What's with the bullying analogy? I don't get this approach, christie uses it too.

In both debates Nikki Haley has come most prepared to stuff Vivek in a locker.

@mehdirhasan He claims that initially they weren't well off so I'm not sure you are addressing this in a fair way.

Ramaswamy opens by claiming he endured hardship as a child. The son of a doctor and an engineer-turned-lawyer, he went to private school.

@TVietor08 Very judgmental of you

Christie referring to Biden as "sleeping with a member of the teacher's union" is gross and disrespectful