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🆕🔥Systematic Review and Noninferiority Meta-Analysis 🌟s @DrToddLee @DrEmilyMcD
Seven vs Fourteen Days of Antibiotics for Gram-Negative Bloodstream Infection
@BradSpellberg #IDXposts
jamanetwork.com/journals/jaman…
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2.8K posts
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@ASPLDD
Antmicrobial Stewardship and ID Pharm D, at University of Toronto
Toronto, Ontario เข้าร่วม Haziran 2015
202 กำลังติดตาม575 ผู้ติดตาม
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So:
Measles can be a big deal, most recover but bad outcomes happen and it still kills people - mostly kids- every year.
People may be blasé about this because the vaccine, which is safe, HAS worked well.
For most, two doses and you are good (prior exposures matter)
10/10
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Hospital antibiotic stewardship programs with designated funding & resources use less fluoroquinolones, anti-pseudomonal agents, and clindamycin
🆕 in @ASHE_Journal
📰doi.org/10.1017/ash.20…
#antimicrobialstewardship
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Thank you @SabraGibbens for your bravery in writing this - right where it belongs, in a peer-reviewed journal. These are strange times. An important and necessary perspective.
@picardonhealth @cmaj @EricTopol
#msdynttrid=VUZwXCneKrXZ5yscNvewRBGudlxCXluVAmeszsrlX3s" target="_blank" rel="nofollow noopener">cmaj.ca/content/196/35…
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Post-hoc bias: a marginal improvement in symptoms tends to encourage patients/HCPs to continue treatment even when the change is coincidental. This can lead to continuing dubious and costly treatments, including unnecessary antibiotics:
jamanetwork.com/journals/jaman… @JAMANetworkOpen
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Drug-related hospital re-admission is common in older adults and many events are preventable. #Antibiotics are one of the top 3 drug classes implicated
link.springer.com/article/10.100…
Toronto, Ontario 🇨🇦 English
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94% of patients with a penicillin allergy who were testing were negative.
Penicillin allergy testing should be a part of preoperative management.
Should Penicillin Allergy Testing Be Included as Part of Preoperative Testing? - PubMed pubmed.ncbi.nlm.nih.gov/37428901/
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Important for providers particularly in GTHA to understand most of this area falls into a lyme endemic zone (along with pockets in SW ON, around Kingston, and Up north). Very different than years past with small endemic zones.
publichealthontario.ca/-/media/Docume…
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During Canada's shortage of children’s fever and pain medications, parents were guided to use weight-based divided doses of adult formulations.
Our new @NEJM study reports this was associated with increased paediatric dosing errors for Tylenol and Advil: nejm.org/doi/full/10.10…
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An underrated reason to go from IV to Po antibiotics is nursing time required to prepare and administer them:
💊 PO 80 seconds
💉 IV 22 minutes
According to @jabicjenkins this time in motion data will help to convince non-stewards to support this important initiative
#ECCMID23
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Poster 625 at #SHEASpring2023: Do you have FOMO (fear of missing organisms)? If your patient with a diabetic foot infection has not had a culture with Pseudomonas in the past year, this has a negative predictive value of 94%. Hold on the pip-tazo!
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Fantastic review I was waiting for
🆕️🔥🔥 @CMIJournal
@CLandersdorfer @GweeAmanda
Prof.Nation
Clinical pharmacological considerations in an early IV to oral antibiotic switch:are barriers real or simply perceived?
Rationale of switch in context of PKPD
clinicalmicrobiologyandinfection.com/article/S1198-…
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The July issue of @PharmacoJournal is online at: buff.ly/2OJ01s6 @ACCP @Stephan55924484 @GI_PharmD @AbrarThabit @canuckIDpharm @DrRaziKeb @ASPLDD @wsueacphs @IDpharmresearch @LusizzZZ
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Vaccination supports #antimicrobialstewardship
COVID-19 vaccination associated with reduced antibiotic prescribing in long-term care IRR 0.7 (95%CI 0.4-1) and community residents IRR 0.3 (95%CI 0.3-0.4)
@uOttawa @UofT_dlsph @ICESOntario @MPHMcMaster @PublicHealthON
Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟@ABsteward
A smart idea, importance of vaccination & antibiotic stewardship 🆕️⚡️⚡️Population Wide Cohort Study 🇨🇦 @CIDJournal Dr.MacFadden COVID-19 Vaccination is Associated with Reduced Outpatient Antibiotic Prescribing In Older Adults with Confirmed SARS-CoV-2 academic.oup.com/cid/advance-ar…
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My husband Tom survived a #superbug infection yrs ago but like many, has several comorbidities. After >3yrs of avoiding #COVID, it hit him hard despite being vaxxed & getting #Paxlovid. He was hospitalized this wknd but is finally on the mend. #COVIDisNotMild #COVIDAwarenessWeek
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Vancomycin is the oldest and most frequently used drug in our arsenal against MRSA
Despite being used for almost 65 years, vancomycin resistance (MIC ≥ 16 μg/mL) is extraordinarily uncommon, with just 52 incidents of VRSA reported worldwide in the past two decades #IDTwitter
Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟@ABsteward
Understanding the interaction between host and pathogen is crucial to the challenge of improving patient outcomes! 🌟Another fantastic review🌟 by @VanceFowler5 et Al @antibioticsmdpi Persistent MRSA Bacteremia: Host, Pathogen, and Treatment #IDTwitter mdpi.com/2079-6382/12/3…
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Mandatory antibiotic indication field is a starting point to support #antimicrobialstewardship in the outpatient setting
ASHE Journal@ASHE_Journal
From @ae_gross @sbleas66 @Papanikrolimus: Implementation and evaluation of the accuracy of mandatory outpatient indication fields - a useful start for benchmarking #outpatient antibiotic #stewardship programs #idtwitter bit.ly/3EEtqxG
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Everyone who's treating MRSA Bacteremia should read this article now!
An excellent review by @VanceFowler5 et Al @CIDJournal
Persistent MRSA Bacteremia: Resetting the Clock for Optimal Management
🌟Excellent figures 🌟
@snap_trial
Thoughts 🤔 #IDTwitter
academic.oup.com/cid/article-ab…
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