Alba Vilchez Acosta

PhD position: Tumor Immunology and Aging – investigate the role of aged myeloid cells in tumorigenesis and immune evasion For more information or inquiries, please contact us at matemaus@vhio.net Application guidelines: vhio.net/vhio-phd-oppor…

❇️ New brain partial reprogramming results from the @OcampoLab and YouthBio: neuron-specific partial reprogramming ameliorates age-related decline in memory and learning: biorxiv.org/content/10.110… 👏 Congratulations @Albavalvil and all coauthors!

❇️ New brain partial reprogramming results from the @OcampoLab and YouthBio: neuron-specific partial reprogramming ameliorates age-related decline in memory and learning: biorxiv.org/content/10.110… 👏 Congratulations @Albavalvil and all coauthors!

Extremely happy to present our new manuscript investigating the role of epigenetic dysregulation as driver of mammalian aging. Congratulations to @calidamrabti and all the authors and collaborators for the fantastic work!! biorxiv.org/content/10.110…

New Preprint Alert! Induction of in vivo reprogramming in C. elegans has negative effects during development and is highly toxic. Congratulations to ⁦@haque_nibrasul⁩ members of ⁦@OcampoLab⁩ and collaborators! The best is yet to come! 🪱 biorxiv.org/content/10.110…

New preprint from the lab. Comparative analysis of previously established and novel reprogrammable mouse strains. Goal: generate new tools to achieve significant organismal rejuvenation and lifespan extension in wild type mice! biorxiv.org/content/10.110…

Happy to share our latest preprint! 🐭🧬We conducted a comparative analysis across multiple reprogrammable strains, tissues, and expression methods, presenting a comprehensive atlas for improving in vivo reprogramming research! @Albavalvil @OcampoLab biorxiv.org/content/10.110…

@AzucenaMS Feliz 8M! 💜

He empezado el día de la mujer cayéndome de la cama al girarme para apagar el despertador. Lo veo como una metáfora de la situación actual de la mujer. Aparentemente bien y cómodas, pero cuando intentas avanzar un poco te h0stias.

Important text by @MathiasJucker about accidental inoculation of seeds that can cause Alzheimer's disease many decades later. Under extraordinary circumstances, Alzheimer’s disease may be transmitted by a prion-like mechanism — yielding insights into both the basic biology of this neurodegenerative disorder and strategies for early prevention. Banerjee et al. describe 8 cases involving individuals who received cadaver-derived human growth hormone for pituitary insufficiency early in life and who, more than three decades later, developed cognitive impairment and/or biomarker changes consistent with Alzheimer’s disease. Source: nature.com/articles/s4159… and nature.com/articles/s4159…

NEWS & VIEWS | Alba Vílchez-Acosta et al. (@unil) comment on: Vit. B12-dependent #metabolism is a limiting factor for cellular reprogramming & plasticity, & could be a therapeutic supplement for improving tissue repair. #vitamins nature.com/articles/s4225…

Online now! Parras et al report a reprogrammable mouse strain with attenuated toxicity as a tool to advance the application and understanding of in vivo reprogramming @aocampox @ParrasAlbert @Albavalvil @Gdesdin @sarapico7 doi.org/10.1038/s43587… rdcu.be/dr9xU

Happy to share our collaborative preprint with @neurocientific and Ruediger Klein. We show that Yamanaka factors induction expand the cortex and enhance cognitive skills. Moreover, their induction protect against neurodegeneration in a mouse model of AD. biorxiv.org/content/10.110…

Very excited to share our Research Briefing where we discuss the latest paper from our lab regarding the “dark side” of in vivo reprogramming @GDesdin. Thank you to the amazing team @ocampoLab @ParrasAlbert @sarapico7 @CalidaMrabti nature.com/articles/s4358…

Impressive work! Overwhelming amount of data, made possible by the amazing team @OcampoLab. Special mention to @Albavalvil, @sarapico7, and @GDesdin. nature.com/articles/s4358…

Excited to share my first postdoc paper!!!! nature.com/articles/s4358… This work has been a team work. I enjoyed working with @Albavalvil and @ParrasAlbert !!! Big thanks to @sarapico7 @CalidaMrabti, @kgiperez. I am grateful for the opportunity to learn from @aocampox about PR.

So happy to share our latest publication from @OcampoLab !! @ParrasAlbert @Albavalvil @GDesdin @aocampox

Very excited to share the latest paper from our laboratory where we investigated the adverse effects of in vivo reprogramming. We hope that our work can help this very promising field to move forward. Congratulations to the authors and collaborators! nature.com/articles/s4358…

Online now! Vitamin B12 emerges as key player during cellular reprogramming dlvr.it/SyxJxw

We are happy to share our News & Views about the recent paper of @martakova and #ManuelSerrano doi.org/10.1038/s42255… Vitamin B12 emerges as key player during cellular reprogramming @Albavalvil @OcampoLab

What's the biggest difference between a neuron from a young vs. an aged primate? It is not the length of the axon and dendrites, but the number of spines available to make contact and connections with other surrounding neurons! 3D recon. made with @ImarisSoftware #neuroscience