Alessandro Bitto

@agingdoc1 @NatMetabolism Thank you so much! The whole idea of mitochondrial transplants as a longevity strategy is very intriguing... and it has just enough sci-fi flare to it to make it even more appealing :D

Mitochondrial transplants to treat mitochondrial dysfunction @BittoAlessandro | @NatMetabolism nature.com/articles/s4225… "A new approach to treating mitochondrial disorders is based on the transplantation of healthy mitochondria, and improves symptoms and survival in a mouse model of Leigh syndrome — a paediatric mitochondrial disease that is characterized by failure to thrive, lactic acidosis, and progressive degeneration..." Fig. 1: Different strategies for mitochondrial transplant.

Mitochondrial transfer nature.com/articles/s4225…

@agingdoc1 what summer break?

So, academics, whatcha doin’ for summer break? science.org/content/articl…

@GeroScienceAGE So nice to see new exciting models for longevity research popping up. I had the privilege of watching Gerald's Master's Defense on this topic and I am really thrilled to see what can be achieved with this platform.

📢New Open🔓 Access Paper Alert Morphological features of the domestic house cricket (Acheta domesticus) for translational aging studies by Gerald Yu Liao & Warren Ladiges et al. rdcu.be/esYyU #aging #morphology #housecrickets #locomotion #SensoryAdaptation #geroscience

@agingdoc1 Thank you for the shoutout!

Ndufs4-/- mice: a testing ground for longevity interventions 🔘"This analysis serves as a useful guide for researchers utilizing this animal in the discovery of effective interventions for longevity and to prevent the onset of disease. 🔘It suggests there may be unprecedented underlying sex-specific differences in patients with Leigh syndrome and further strengthens the connection between normative aging and mitochondrial dysfunction." Jackson Nuss, @mkaeberlein, @BittoAlessandro, @GrilloAnthonyS link.springer.com/article/10.100…

@GrilloAnthonyS @mkaeberlein Happy reading and let us know what you think. 7/7

This work stems from @GrilloAnthonyS’s idea to compile over a decade worth of data in these mice. We are grateful for the help of countless undergraduate students who gathered all the data, and for @mkaeberlein who funded the majority of the studies these data are taken from. 6/n

Excited to share our latest publication in @GeroScienceAGE: "Ndufs4−/− mice: a testing ground for longevity interventions". link.springer.com/article/10.100…. In this paper, @GrilloAnthonyS and I introduce a transgenic mouse model exquisitely sensitive to longevity interventions. 🧵 1/n

Congratulations to Rhea Misra for her poster presentation at the Mary Gates Undergraduate Research Symposium!

See their work on @eLife at: elifesciences.org/articles/96926

With the holidays I missed the boat on sharing this little eLife Magazine piece I wrote last month. A small commentary on a very nice paper by Dylan Sarver and Will Wong at Johns Hopkins. elifesciences.org/articles/105191

Also, follow the link for the cutest Ella interview ever.

I don't usually post about private stuff on Twitter/X but I feel this is important.@SeaPubSchools is planning on closing my children's elementary school upon budgetary concerns. The aftermath for my son and other children on the spectrum could be dramatic. kiro7.com/news/local/par…

@BrestoffLab @UMDF I haven't been to the @UMDF meeting ever since it was in Seattle in 2016. It might be time to change that.

The program for this meeting is exciting! #mitochondria #obesity #diabetes #mitochondrialdiseases #mitophagy #mitodynamics #mitotransfer #mitotransplants #mitomics and more Join us in St Louis next Juneby the Arch! #MitoMed 2025 @UMDF

@agingdoc1 Thank you for the shoutout! It was a privilege to read the original work ahead of publication.

Mitochondrial transplants to treat mitochondrial dysfunction @BittoAlessandro nature.com/articles/s4225…

Very grateful to @NatMetabolism for the opportunity to share my views on this exciting paper.