Mahek Shah, MD

So excited to announce my new medical podcast HeartSuccess on cardiovascular disease is available on iTunes, Google Music & major podcast services. Please LISTEN, SUBSCRIBE, RATE US and SPREAD the word if you enjoy it!#heartsuccess #cardiology #podcasts #medicalpodcast #Health

Tell me you don't see patients without telling me you don't see patients Writers have lost touch with reality #Lipidguidelines

@DrMakaryFDA Whatever happened to Primum non nocere #FaustianBargain

A year ago, Dr. Prasad came to the FDA to implement 4 major long-lasting reforms: 2-to-1 pivotal trial requirement, national priority reviews, a risk-stratified covid vaccine framework, & the new plausible mechanism framework for ultra rare diseases which we launched last week. Also, under his leadership, his center hit a record number of approvals in Dec. He got a tremendous amount accomplished within his one-year sabbatical from UCSF and will be returning back to his academic home later next month. We will name a successor before his departure. I want to thank him for his service and personal sacrifice to take time away from his family.

The 800-pound gorilla HHS Appointee Study (2023): A study in Health Affairs tracked appointees across the Department of HHS (includes FDA) between 2004-2020. It found that 32% of government appointees exited directly into private industry at the end of tenure #revolvingdoor

@DutchRojas My attempt on Monday @ACHE2026 to get a solid answer from Dr. John Whyte resulted in a vague and tangential response.

The American Medical Association represents less than 15% of practicing physicians. It controls the CPT code system that governs how every physician in America gets paid. It receives licensing fees from that system regardless of AMA membership. It lobbies on behalf of positions most physicians actively oppose. It endorsed policies that accelerated consolidation, employment, and the commoditization of physician labor for decades. The AMA doesn’t represent physicians. It licenses the billing infrastructure they’re forced to use. These are different things. The conflation is not accidental.

@AcademicTruther Raises serious ethical and legal red flags #whatprogram

People realize that one way to game the heart transplant system is to implant surgical Bi-VADs (i.e. CentriMags) insetad of a durable LVAD, and thereby attain status 1 for patients. No hemodynamic criteria need to be met. I know of one program doing exactly that.

@ebtapper Echo is unhelpful because the interpreter is often wearing blinkers.

Being a hepatologist means you diagnose a LOT of heart failure 1. Ascites, often with high total protein 2. ALT > 400 is most often due to ischemic hepatitis. This is caused most by venous congestion and less by systemic hypotension. echo often unhelpful

Our team is one of only 50 Platinum-Level ECMO programs worldwide, as designated by ELSO. This is the standard we strive for every day. #MethodistSanAntonio #ECMO #ELSO #hftransplant linkedin.com/posts/mahek-sh…

@AcademicTruther Tests can hardly prevent that but its a start

If you cannot pass a cardiovascular board certification examination, you shouldn't be a cardiologist. FULL STOP. It's not that hard of a test. It tests BASIC knowledge. The public deserve to know their doctor is competent. STOP the dumbing down of medicine.

pVO2 recovery by @GLewisCardiol - an important new measure on CPET. Derivation from an observational study at MGH, application in SEQUOIA-HCM shows how aficamten improved pVO2 recovery compared to placebo An excellent read here ahajournals.org/doi/10.1161/CI… #CardioTwitter

Excited to lead our world class Pulmonary Hypertension team Officially, PHA accredited center of excellence!! Multidisciplinary team w/ heart failure, pulm critcare & lung transplant expertise on board Methodist Hospital, San Antonio, TX #PHAaccredited #CenterofExcellence #PAH

Double bagel in a final. Thats new. #Wimbledon2025

The curse has been lifted. Championship glory after 36 years. #WtcFinal2025 #AUSvsSA

(1/4)Disappointing - if not surprising - news on the AL #amyloidosis space, with the failure of birtamimab to change outcomes in advanced AL amyloidosis. 🙁Thoughts below…

3 out of 7 newly diagnosed ATTR-CM patients that I saw in 1 day didnt have ATTR-CM (2 on therapy). Just really tough to interpret PYP scans with blood pooling, and due to cavity size and shape they simply appeared as myocardial uptake to those reading them. That is why we are running REVEAL (Evuzamitide in suspected cardiac amyloidosis). Cant afford making such mistakes. clinicaltrials.gov/study/NCT06788… #CardioTwitter #CVNuc

Must’ve missed all those chapters on Excited delirium in Harrisons #TasersKill

I missed this presentation. Higher than we would have expected in terms of positive rate in carpal tunnel release. Important data #ACC25 #CardioTwitter #MEDIQACC25

Big news: A new bill supporting Physician-Owned Hospitals just dropped. It is a turning point. If passed, this bill removes key restrictions on physician-owned hospitals, especially those that serve rural and underserved areas. What can you do? •Contact your representative •Join advocacy groups like the PHA. •Share this post to spread awareness •Build or partner with POHs in your region We don’t need fewer hospitals. We need better ones—physician-led, transparent, efficient, and community-focused. Let’s bring healthcare back to the hands of those who deliver it. congress.gov/bill/119th-con… #physicianled #ruralhealth #POH #healthcarefreedom @RepLouCorrea @RepMGriffith @RepKevinHern @RepGonzalez @RepJohnJoyce @gopdoctors @physicianhosp

Low vs moderate-intensity anticoagulation for VV #ECMO 🔍 SAFE-ECMO pilot trial; 3 centers across 🇺🇸 💉 intermittent SC anticoagulant (doses for DVT prophylaxis) vs traditional approach to anticoagulation with continuous, goal-titrated, infusion 🩸major bleedings 8.3% in low vs 28.6% in moderate-intensity group 🩸thromboembolic event 8.3% vs none 🪦 mortality before discharge 0 vs 14.3% @accpchest 🖇️ bit.ly/3DLsiLF

@realEstateTrent @sprkhost_austin Airbnb Vrbo consistently better over a hotel Cant beat the space Be picky Havent had a bad experience so far

@sprkhost_austin Nah not my cup of tea. Need to be able to call room service, someone to clean each day, etc. did Airbn a few years ago - it was winter and the heat wasn’t working. Could not get the owner to fix that day - we got in the car and drove home, and that was the last time.

Where do families w/ three kids stay when they travel? Two hotel rooms? Pay 3x for a large suite? Airbn? Feels like the travel budget is 2x for fam of 5 vs 4.