JonRowley.eth

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JonRowley.eth

JonRowley.eth

@JonRowley

Founder & Buidler @RoosterBio. Industrializing the Advanced Therapy supply chain. Cell & Exosome Manufacturing, Longevity, Crypto/Web3. Tweets are my own.

New Tokyo, 10KTF (& Maryland) Katılım Mart 2008
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Allie K. Miller
Allie K. Miller@alliekmiller·
oh wow - i went to the sold out Open Claw meetup in NYC last night. let me tell you what i learned. 1) not a single person thinks that their setup is 100% secure 2) one openclaw expert said he has reviewed setups from cybersecurity experts and laughed. his statement to me was: "if you're not okay with all of your data being leaked onto the internet, you shouldn't use it. it's a black and white decision" 3) pretty much everyone is setting up multiple agents, all with their own names and jobs and personalities 4) nearly everyone used "him" or "her" to refer to their claws, even if they had robot-leaning names. one speaker suggested to think of them as "pets, not cattle" 5) one guy (former finance) built out a whole stock trading platform and made $300 his first day - he brought in a *ton* of personal expertise (ex: skipping the first 15min of market opening) and thought the build would be much worse without his years of experience in finance 6) @steipete is basically a god to everyone in that room... also the room had 2021 crypto energy - i don't know if that's good or bad 7) token usage is still a problem - spoke to one person who's spending $1-$2k a month on openai plans, very token optimized. he said he is going through ~1B tokens per day across all of his claws (there is a chance i'm misremembering and it's actually 1B per week, but i'm pretty sure it was daily). 8) people are very excited for more proactive ai (ai that prompts *you* as opposed to the other way around) - one guy said he receives a message in discord, he doesn't know whether it's from a human or an ai, he doesn't care about distinguishing between the two, and he replies in the same way regardless 9) i asked if people are happy - they said they're joyful and stressed at the same time 10) i asked if people feel they have agency - they said they feel fully in control and completely out of control at the same time 11) i would love to see more women at these events - the fake promises of ai democratization feel especially painful in a room that's out of balance with even the standard tech ratio (i think standard is about 25-30%, this was maybe 5%) 12) i asked if it changed people's daily habits/schedule - everyone said their sleep has gotten worse since harnesses came out (but about half wondered if it was something else in their life/state of our world) 13) general consensus is that the agents are not reliable enough on their own or lie often (like telling you they finished a task when they didn't) - solutions included secondary agents to check on the first, human checking, or requiring more standardized info from the agent (ex: if it's a bug they're fixing, make them reference an issue number) 14) a hackathon winner (neuroscience phd) presented his build (a lab management dashboard with data analysis and ordering) - he had never coded or built anything a few months ago 15) everyone agreed prompting is dead - disagreement on what replaces it (context engineering, harness engineering, goal-based inputs) 16) people love having ai interview them for big builds and delegating part of the product research to ai. only one person talked about coming to ai with a full laid out plan and just asking the ai to execute. ai-led interviews is a welcomed and preferred interaction mode. 17) watching ai agents interact with each other was a highlight for a lot of attendees - one ai posted in slack saying it ran out of tokens, another ai replied telling it to take a deep breath in and out. 18) agents upskilling agents was very cool. one ai agent shared skills with its little agent friends via github. 19) several speakers had openclaw literally building their presentation during the event itself. one speaker even had openclaw code a clicker for her phone so she could control the preso away from the podium 20) wouldn't say model welfare (or agent welfare) is a prioritized topic among the folks i chatted with - language like "oh i could kill this agent whenever i want" and not "gracefully sunset" 21) i asked if it felt like work or play - one speaker said "it's like a puzzle and a video game at the same time" this was just the tip of the iceberg, honestly. also hosted a Claude Code meetup this week with @TENEXai / @businessbarista & @JJEnglert and learned equally helpful methods, frameworks, and insider tips. what a time to be alive. surround yourself with people going deep into this stuff - it will pay dividends throughout the year.
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Garga.eth (Greg Solano)
Garga.eth (Greg Solano)@CryptoGarga·
some thoughts on APE: Staking for ApeCoin ends today. I think that's a good thing longterm. Staking had an admirable goal: align BAYC holders and long-term believers with ApeCoin. In practice though, it created a hyperinflationary setup and constant sell pressure that didn't really benefit anyone. So we’re moving APE to a usage-driven economy instead, and making the token deflationary. I’ve said this before, but I think generalized L2’s without a killer app are a dead end. A chain is only as good as the thing on it that people actually want to use. For APE, that killer app is Otherside. We’re already seeing how Otherside can be a home for communities across crypto. And it’s the perfect canvas for us at Yuga to partner with some of the biggest companies and artists in the world, from Amazon to Daniel Arsham. Going forward, we’ll keep evolving Otherside into the best place for creators to launch their own game or social experience, with crypto quietly doing the heavy lifting in the background: permissionless ownership, creator royalties, and open economies. That means incentives should line up so ApeCoin wins if Otherside wins, and vice versa. To start, from now on all gas spent on transactions on ApeChain will be burned. So that activity on Otherside permanently reduces the supply of APE. This will be small to start, of course, and not as flashy as staking. But it’s the start of a real economic loop, where value comes from what people build and use. This is just the foundation. There’s a lot more coming to make Otherside more robust, scalable, wild and fun. Along with ways to make sure the economic loop between Otherside and APE is stronger than ever. More to share on all that soon.
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beeple
beeple@beeple·
could not be more proud of our team at the studio who absolutely destroyed this shit so fucking hard. this would have IN NOW WAY been possible their hard work and dedication to making everything look like magic. For those of you who peaked behind the curtain or interacted with Scott, Tyler, Ricky and Jeremiah this week you know these guys were absolutely busting their asses to make this a massive success and I could not be more appreciative of their professionalism and inspiring work ethic. Honored be on this team!!! <3 💪💪💪
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Chikai
Chikai@lifeofc·
I think people are starting to realize that the $69M Christie’s sale wasn’t just a fluke. @beeple wasn’t a fly-by-night artist who got lucky but he has done it again at @ArtBasel Zero 10, bringing the world’s attention to digital art And the part that most don’t see and matters even more (at least to me) is that he’s not just here for himself but he shows up for other artists in the community. He showed up for @lphaCentauriKid‘s Broken Keys exhibition in NYC. He showed up for @artblocks_io in Marfa. And those events didn’t even exhibit any of his works like @ToledoMuseum and @LACMA did where he also showed up and was so approachable and of course funny. He even pranked @benskaarx at a bar in Toledo! And this is on top of the community events he throws at his own expense at Beeple Studios. I have only started to get to know him a bit better this past year, but the more I know the more I’m impressed with Beeple. I’m happy he is the at forefront leading the way and helping to shine the spotlight on so many artists in our space.
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dutchee
dutchee@dutchee·
ULTIMATE THREAD: BAYC OTHERSIDE 🧵 I analyzed every tweet + source I could find and listened to the 4 most recent Twitter Spaces from Garga and Figge Years in the making and it launches this month 👀 Built on ApeChain and Powered by ApeCoin Here's ALL THE ALPHA you missed 👇
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Fred Ehrsam
Fred Ehrsam@FEhrsam·
I founded @nudge with @quintinfrerichs. We’re building an ultrasound headset to enhance human experience. Press a button to shift your brain state: go to sleep, boost focus, break habits, elevate mood, etc. We believe this device has the potential to improve people’s daily lives more than any other technology. Ultrasound neuromodulation has the ingredients necessary for a near-term mainstream consumer product. Research progress in ultrasound has accelerated in the last few years and has begun to produce promising results. It's not just for those with diagnosed conditions - everyone can benefit from better brain function. Safety is a top priority and a large advantage of ultrasound. It has been used for decades for sensitive applications like imaging children in the womb in addition to being studied directly for neuromodulation at similar low power levels. We’re currently a scrappy team of 11 engineers and scientists who previously worked at places and on projects like the Vision Pro, Neuralink, SpaceX, and top university labs like Stanford. If you’re a mechanical, electrical, or software engineer who wants to build a device to improve people’s daily lives beyond what is currently possible, reach out: info@nudge.com. For updates on our progress, follow @nudge.
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The Tennis Letter
The Tennis Letter@TheTennisLetter·
Venus Williams is honored with her own Barbie doll. Her doll is a part of the new ‘Role Model’ line-up of dolls, which celebrates female sporting icons. Very deserved. 💖
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Peter H. Diamandis, MD
Peter H. Diamandis, MD@PeterDiamandis·
Just completed my 2nd of 6 "Therapeutic Plasma Exchange (TPE)" treatments at Fountain Life. My "longevity oil change" replacing 2.2 liters of gunk (inflammatory factor etc). Check it out www. Fountainlife.com
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Peter H. Diamandis, MD
Peter H. Diamandis, MD@PeterDiamandis·
Age-reversal: yes or no? Would you do it if you could?
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Kenneth W Witwer (he/him)
Kenneth W Witwer (he/him)@KennethWWitwer·
A reviewer recently ruled "reject" on a submitted paper since we measured small #ExtracellularVesicles <100 nm in diameter by #NanoFlow. In the reviewer's opinion, this finding was invalidating, since "classical extracellular vesicles have a size of greater than 100 nm." In fact, many (often most) EVs are smaller than 100 nm in diameter. If you are measuring a larger average population size, this may simply be due to the insensitivity of most optical methods to smaller particles.
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