Maverick Matters

@sweatystartup Indeed. Similar story on leucine

Methionine is the amino acid I’m worried about. Data isn’t conclusive yet, but this is scary. Lots of smart longevity docs are reducing protein in clients because of the data below. mTOR grows muscles, but it also accelerates cellular aging.

Normal people eating 150-200 grams of protein daily will go down as as big of a disaster as the lead pipes that took down the Roman Empire.

In 2003, next to footage of the US bombing Iraq, Secretary of Defense Donald Rumsfeld said on TV that the footage was a kind of postmodern, subjective non-truth that was "not taking place." I don't think the Trump people have someone who can operate on this level

@SahilBloom Protein I mean

@SahilBloom Insanely impressive. You’re doing almost 3x g/kg BW? Whoaahh

What’s the single most underrated exercise? I’ll start: Heavy walking lunges. Full body strength, balance and stability, plus cardio at higher rep ranges.

@INArteCarloDoss Perspicacious Mo. As always 😂

This mfer cracks me up

@Alan_Couzens damn, our loss - will miss you - be well!

With that said, I'm going to be spending more time on the #MADcrew forum and less here. It's becoming readily apparent that this place simply isn't good for your long-term physical or mental health... forum.madcrew.app/t/social-media…

@Alan_Couzens Yeah. Considering tossing my whoop tbh…

Unpopular opinion o' the day: #HRV (alone) is not powerful enough to determine when an athlete should take recovery. Even more unpopular opinion o' the day: This is why we need composite measures that factor in other markers like readiness scores. Perhaps the most unpopular opinion o' the day: Current commercial (wearable) options for readiness algorithms are largely bullshit, and you're better off building your own. #### As a starting point, a simple even weighting of HRV, RHR, Soreness, Fatigue, Life Stress & Mood will outperform HRV alone and all commercially available options.

"At the single-fiber level, then, geometry and physics would predict that a fiber cannot be both massive and maximally oxidative" 👏 Big or fit? Your choice.

"hey man I know you're worried the trucking company might lay you off soon and you're behind on the mortgage, but Kalshi is offering 3 to 1 on 46,000+ trucker layoffs in Q1 so you might want to hedge that risk out"

@ColdBloodShill Man

This year (2025): Gold +60% (best year since 1970s) Silver +104% (best year since 1970s) NASDAQ +20% SPX +16% and BTC -7% ETH -25%

@EricTopol Thanks. But actually worthwhile if current treatments are ineffective (of course individuals should anyway do lifestyle+ you advocate)?

p-tau217, the breakthrough blood test, prediction of amyloid-β burden and Alzheimer's disease in people with no symptoms, no cognitive impairment jamanetwork.com/journals/jaman…

@goodalexander lol yes. Damn tasty tho

which means of course the only thing worse than American food is Hawker food

I'm pretty sure seed oils are actually bad from you back from Singapore for a month - not inflamed, stronger, and less on edge

@goodalexander They loaded u w seed oils in SG u mean?

@EricTopol @grok summarise the findings and propose a sensible takeaway. On net is low protein diet a key contributor to health span and longevity? What constitute low protein? Does cycling protein intake / staggering it make a difference ?

Low protein diet's beneficial effect on aging of 40+ different tissues in the mouse model and in humans. Extreme protein deficiency promoted inflammation cell.com/cell/abstract/…

@TheFlowHorse Greet footwork!

Can’t put a price on this.

@based16z 🔥

you need to be on his level of locked in

Is dark chocolate good for you? "Sadly for chocoholics, the health claims for dark chocolate come from wishful thinking and sly marketing, not the findings of science." economist.com/science-and-te…

Nothing to see here ;-) @Nature feature, by @SilverJacket nature.com/articles/d4158…

its like 2017 ICOs except its the biggest companies in the world this is fine