Poulikos Poulikakos
217 posts

Poulikos Poulikakos
@Poulikos
Researcher focused on cancer and immune signaling and targeted therapies. Professor with tenure @TischCancer @SinaiImmunol
New York Katılım Kasım 2008
650 Takip Edilen516 Takipçiler
Poulikos Poulikakos retweetledi

Our lab is expanding and hiring both a postdoc and staff scientist! We study how metabolism and cell cycle states drive tumor progression, therapy response, and immune interactions. Philly is a great place to live and do research! See more at: airdlab.com.
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Thrilled to share our new @NatureGenet paper! We mapped human skin at single-cell spatial resolution and found that anatomy is encoded in cell states and neighborhoods, led by PhD student @paularstrpo. Link: nature.com/articles/s4158…
1/9
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New in Cancer Genes and Networks: RAS Mutation–Specific Responses to Paralog- and State-Selective RAS Inhibitors doi.org/10.1158/1541-7…

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@FaltasLab @WeillCornell @Cornell @HeartBobH @DrScottTagawa @DrDavidNanus @DrChoueiri @ChongPan_HMS @montypal @HsiehLab @PGrivasMDPhD @MarkARubin1 @ElementoLab Congrats Bishoy!
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#Tenure! I’m overwhelmed with gratitude to share that I’ve been awarded tenure at @WeillCornell @Cornell
I’m deeply grateful to my family, mentors, collaborators, and the many friends and colleagues in the field who have supported me in so many ways over the years. Too many names to list here! Thank you to every single one of you.
To the #FaltasLab members and alumni, your creativity, persistence, and teamwork made this possible. You’ve made me better in every way, and it’s a privilege to witness your growth and successes. This truly belongs to all of you.
As I reflect on this journey, I’m reminded of the challenges we’ve overcome, and of the profound privilege of being a physician-scientist: caring for patients with #bladdercancer, doing cutting-edge science, and mentoring the next generation of bright minds.
The next chapter is about asking bigger questions and building new bridges, between science and medicine, and between people! @WCMEnglanderIPM @WCM_MeyerCancer
With passion, persistence, and humility, onward!


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Pleased to share our latest study on emerging RAS-targeted therapeutics, now published in Molecular Cancer Research.
Molecular Cancer Research@MCR_AACR
#OnlineFirst: Paralog- and state- selective RAS inhibitors are differentially effective towards RAS-mutant tumors. doi.org/10.1158/1541-7… #RASInhibitor @Poulikos @ChrAdamopoulos @ProfGavathiotis @IcahnMountSinai @broadinstitute @UMRogelCancer @EinsteinMed
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Happy to share my lab’s work out today in @Cancer_Cell demonstrating that multiple myeloma relapses after CAR T therapy frequently express low BCMA levels. We develop novel SEMA4A-directed CAR T cells eradicating MM, especially under BCMA low conditions.
authors.elsevier.com/a/1lvYf_YwcvnX…
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Immunology takes center stage again at the #NobelPrize! Congratulations to Mary Brunkow, Fred Ramsdell & Shimon Sakaguchi for uncovering how regulatory T cells maintain immune tolerance—a discovery that transformed our understanding of autoimmunity and cancer immunotherapy
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Congrats to all on a labor of love. I recall "pd-1 is boring" as a grant review comment. Not so boring in fact...
nature.com/articles/s4159…
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We are delighted to share our lab's latest paper on the RAS GTPase RIT1 just published @CR_AACR!!
In this work, we explored the role of the RIT1 oncoprotein in lung cancer and propose different therapeutic strategies to inhibit downstream signaling and RIT1 directly.
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I am thrilled to share that the first preprint from my lab is now available on bioRxiV! In this study, our team elucidates the role of autocrine ligands in the aberrant behavior of oncogene-driven lung cancer.
biorxiv.org/content/10.110…
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@ZeynepHG @CellPressNews @EsaiMyvizhi @SinaiGenetics @IcahnMountSinai @TischCancer @SinaiImmunol Congrats Zeynep! Impressive work!
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Our study out in Cell @CellPressNews
on how germline variants shape tumors: Precision proteogenomics reveals pan-cancer impact of germline variants. Great work by @EsaiMyvizhi from @SinaiGenetics @IcahnMountSinai @TischCancer @SinaiImmunol &great collab sciencedirect.com/science/articl…

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BREAKING: Federal judge temporarily blocks NIH indirect costs rate cap issued Friday as applied to states that sued over the act this morning.
Judge Angel Kelley, a Biden appointee, ordered further briefing and set a hearing on Feb 21 in the case. storage.courtlistener.com/recap/gov.usco…


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Our review article, "Resistance Mechanisms and Therapeutic Strategies for CDK4/6 Kinase Targeting in Cancer," is out today in @NatureCancer ! Check it out.
rdcu.be/d75mG
@ProfGavathiotis @ChrAdamopoulos
#PROTACs #CDK46 #CDK2 #Oncology #CancerImmunotherapy
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Learn from the expert!
Medical Digest & Congress Report@MedicalDigestCR
🎥 Joshua Brody, MD discusses the advancing field of bispecific antibodies in third-line relapsed/refractory follicular lymphoma at ASH24. -> medicaldigest.org/scientific-con… @JoshuaBrodyMD @IcahnMountSinai @ASH_hematology #hematology
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