Boris D Heifets

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Boris D Heifets

Boris D Heifets

@TheBorisLab

Anesthesiologist, neuroscientist, amateur psychiatrist. I know where the most powerful psychotropic drugs in the hospital are.

Stanford, CA Katılım Kasım 2018
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Boris D Heifets
Boris D Heifets@TheBorisLab·
SPIKED: Stanford Placebo vs Intraop Ketamine Evaluated for Depression. We masked ketamine with surgical anesthesia in depressed patients. Full details now published, peer review pending. Huge antidepressant response in both groups. @TheresaLii 1st auth bit.ly/3LMAueK
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Bertha madras
Bertha madras@madras_bertha·
A fighter pilot? Capt Joseph Emerson sat in cockpit jump seat, tried to turn off fuel to both engines at 29,000 feet, 48 hours after taking psilocybin. We are marching in dangerous terrain, with yet another hyped “magic bullet” that can destroy as unpredictably as it can help.
Mattha Busby@matthabusby

As the war on drugs approaches its end, a new doctrine could soon take hold: psychedelic drugs for active-duty soldiers suffering from PTSD. 'Our men and women in uniform deserve every tool available to heal and stay in the fight.' Latest for @guardian theguardian.com/us-news/2026/a…

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Xue Zhang
Xue Zhang@warmxue·
Looking forward to a lively discussion on this work today. Please stop by Poster S217 — I’d love to connect!
Stanford PMH 🧠@Stanford_PMHW

Can brain circuits predict who benefits most from MDMA-assisted therapy? 🔍🧠 Catch Dr. Xue Zhang (@warmxue) at the @SOBP Poster Session presenting: S217: Circuit Stratification of MDMA Response: Convergent Evidence from Amygdala and Mediodorsal Thalamus Function New findings highlight how baseline brain activity—especially in the amygdala and mediodorsal thalamus of the negative affect circuit—may help explain variability in response, pointing toward more precise, personalized approaches for PTSD treatment. 📅Sat, May 2 | 5–7 PM EDT 📍West Side Ballroom Stop by to explore how circuit-based insights are shaping the future of precision psychiatry in the context of MDMA-assisted therapy. #PTSD #fMRI #PrecisionPsychiatry #NegativeAffectCircuit #SOBP2026

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Stanford Anesthesiology
Stanford Anesthesiology@stanfordanes·
A new paper takes a closer look at how ketamine works in the brain, and whether its different effects can be separated. Researchers compared ketamine given to people who were awake versus under general anesthesia, tracking brain activity with EEG.
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Stanford PMH 🧠
Stanford PMH 🧠@Stanford_PMHW·
Can brain circuits predict who benefits most from MDMA-assisted therapy? 🔍🧠 Catch Dr. Xue Zhang (@warmxue) at the @SOBP Poster Session presenting: S217: Circuit Stratification of MDMA Response: Convergent Evidence from Amygdala and Mediodorsal Thalamus Function New findings highlight how baseline brain activity—especially in the amygdala and mediodorsal thalamus of the negative affect circuit—may help explain variability in response, pointing toward more precise, personalized approaches for PTSD treatment. 📅Sat, May 2 | 5–7 PM EDT 📍West Side Ballroom Stop by to explore how circuit-based insights are shaping the future of precision psychiatry in the context of MDMA-assisted therapy. #PTSD #fMRI #PrecisionPsychiatry #NegativeAffectCircuit #SOBP2026
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Harrison Chow, MD, MS, FASA
Harrison Chow, MD, MS, FASA@drpuppychow·
open.substack.com/pub/drpuppycho… Starting a new blog - "The Anesthesia Dreamscape" on Substack. Collection of original observations and notes about the phenomenon of anesthesia dreaming. Please follow and subscribe, I will try to post and answer questions regularly there for consolidation-sake.
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Manoj Doss not exist
Manoj Doss not exist@ManojDoss·
I'm looking for a post-bac research assistant to help run our studies on the impact of psychedelics on memory! Preferably with an interest in cognitive neuroscience (not just psychedelics or clinical research) and knowledge of coding/data analysis. utaustin.wd1.myworkdayjobs.com/UTstaff/job/UT…
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Joe Hardy
Joe Hardy@jlhardyphd·
Imagine being in a magic mushroom study, and you get the placebo. Womp womp. This leads to what researchers are now calling the "knowcebo" effect. This wipes out the impact of placebo controls in these studies. @psybalazs : podcasts.apple.com/us/podcast/cog…
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Eric J. Nestler, MD, PhD
Eric J. Nestler, MD, PhD@EricJNestler·
I had the honor of a lifetime this evening by being inducted into the National Academy of Sciences. I want to thank the many PhD students and postdocs in my lab over the past almost 40 years whose hard, creative, and impactful work made this possible. @SinaiBrain @IcahnMountSinai
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BryanRoth
BryanRoth@zenbrainest·
Mechanism-guided identification of antidepressant G protein-coupled receptor drug targets: Cell cell.com/cell/fulltext/…
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Boris D Heifets
Boris D Heifets@TheBorisLab·
In a sane world, this study would be seen as a signal to learn more- not as the primary basis for a massive shift in policy. I’ll say though, it rly does take an EO that would make it possible to study Ibogaine in the US- the FDA has taken a zero-risk approach, trials are expensive and slow as a result
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Michael Ostacher, MD, MPH
Michael Ostacher, MD, MPH@RecoveryDoctor·
@TheBorisLab A different take on what you are saying. Look at what the people who got open label ibogaine study (that did not include everyone who got ibogaine btw). If you want people to get better on ibogaine, fund trips to Mexico & Stanford, give them massages, etc. x.com/RecoveryDoctor…
Michael Ostacher, MD, MPH@RecoveryDoctor

@cremieuxrecueil It’s even more concerning with regard to interpreting subjective data with no control. Have a look at the methods for the people in the study. Not only did they get three trips to The Farm, they got all these other activities and interventions — and had all their travel paid for.

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Boris D Heifets
Boris D Heifets@TheBorisLab·
Dead on. Step 1 to understanding what Ibogaine and psychedelics can do is easing regs and promoting science. I hope the same enthusiasm extends to creating and sustaining the social and psychological supports needed to “scale”
Franklin King MD@KingFranklinIV

The contradiction at the heart of Republicans’ embrace of psychedelics Without additional resources, psychedelics like ibogaine can’t support recovery, mental health statnews.com/2026/04/20/tru…

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ARPA-H
ARPA-H@ARPA_H·
America is in the middle of a mental health crisis. Half of all Americans will experience a mental or behavioral health condition, with even higher rates among veterans. Yet medical professionals still lack the objective tools needed to determine what treatments work and for whom. Too many patients are left cycling through care without clear answers. ARPA-H’s EVIDENT program is working to change that by developing new ways to measure treatment effectiveness and evaluate emerging therapies, including psychedelics. Thank you @POTUS @WhiteHouse and @SecKennedy for elevating this as a national priority through Saturday’s executive order to accelerate medical treatments for serious mental illness. ARPA-H was built to take on challenges like this and deliver Americans transformative care at rapid speed. arpa-h.gov/news-and-event…
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Bruce Lambert
Bruce Lambert@bruce_lambert·
Larger sample sizes. More psychedelically naive patients. More long term follow up. More complete and honest reporting of adverse effects. More careful blinding. More transparent consent and more research on whether patients think the consent was true and useful when viewed after the trip.
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Boris D Heifets
Boris D Heifets@TheBorisLab·
Real world studies, long term studies in the VA system, better reimbursement for interlocked therapy / coaching / medical care and intense interventions like, perhaps, psychedelic treatment, creative exploration of what kind of things we can do on-drug to engage the incredible range of patient issues…
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Genevieve Jurvetson
Genevieve Jurvetson@gjurvetson·
Thx Leanne for your contributions to this historic event. One of the most touching parts of the signing ceremony was @NIHDirector_Jay’s tribute to Stanford Professor @NolanRyWilliams whose incredible research on ibogaine was referenced by @POTUS. Thx so much Jay!💗 President Trump gave us a commemorative coin for Nolan which we are sending to Nolan’s Mom (who was invited to the Oval Office to honor the work of her son.)
Genevieve Jurvetson tweet mediaGenevieve Jurvetson tweet media
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Stanford PMH 🧠
Stanford PMH 🧠@Stanford_PMHW·
Today, the @WhiteHouse issued a new Executive Order on “Accelerating Medical Treatments for Serious Mental Illness” a major step toward expanding access to innovative, evidence-based care. Dr. Leanne Williams (@LMWilliams_PhD) was at the White House for the signing and noted: “This is a much needed bold move for precision mental health… accelerating access to personalized, targeted treatments. Our work is developing brain-based tests to understand why treatments work and who they’ll be most effective for. With this mandate, we can accelerate saving lives and getting people well sooner.” A meaningful moment for the future of precision mental health. Watch this morning's press conference to learn more: youtube.com/watch?v=8xrI-_… #precisionmentalhealth #neuroscience #research #stanford #mentalhealth
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Matt Burke
Matt Burke@MattBurkeMD·
There is converging evidence that brain networks and neurotransmitter systems modulated by placebo effects may overlap with the therapeutic mechanisms of many psychiatric treatments. There are critical implications of this re: potential ceiling on shared effects, synergism etc!
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Keşfet

@madras_bertha @warmxue @SOBP @psybalazs @SinaiBrain @IcahnMountSinai @POTUS @WhiteHouse