Ashish Aneja MD FACC FAHA FASE FSCMR

A poll for my noninvasive CMR peeps! What agent(s) do you use most frequently for CMR stress? @HeartDocSubha @DrRyanPDaly @AkhilNarangMD

Some new evidence comparing middle-aged US population groups with MASALA and MESA data…

At what age does CVD risk begin to diverge among South Asians compared to other groups? Understanding risk trajectories allows us to identify people who can benefit from prevention before CVD events.

Among patients with #Stroke and #PatentForamenOvale, the PASCAL classification system identified those likely to benefit from closure and those at risk of increased atrial fibrillation. ja.ma/4bo2Rg4

Great to celebrate our Preventive Cardiology Guideline release with my colleague & key writing group member ⁦@SethShayMartin⁩ - special thanks to the Prevention Dream Team Writing group & my co-chair, the Amazing Dr. Pam Morris

In an international, randomized trial involving patients with acute venous thromboembolism, the risk of clinically relevant bleeding was significantly lower with apixaban than with rivaroxaban during the 3-month treatment period. Full COBRRA trial results: nejm.org/doi/full/10.10…

Finally published: the COBRRA trial, the first randomized head-to-head comparison of major DOACs — something the companies would never have done themselves, as a direct confrontation goes beyond their commercial interests. This was driven by independent investigators. The results somewhat support the idea of apixaban being the “safer” DOAC. That said, the list of study limitations is long, and for me, labeling something as “safe” is not enough — after all, even placebo is “safe” when it comes to bleeding. nejm.org/doi/full/10.10…

Low-Dose Rivaroxaban to Prevent Left Ventricular Thrombosis After Anterior Myocardial Infarction The APERITIF Randomized Clinical Trial In this multicenter randomized clinical trial among patients with anterior STEMI, the addition of low-dose rivaroxaban to DAPT did not demonstrate a statistically significant reduction in LV thrombus formation at 1 month but did increase minor bleeding #Cardiology #MedTwitter #CardioTwitter #HeartHealth #Healthcare @JAMA_current @CMichaelGibson @DrMarthaGulati @hvanspall @iamritu @AndrewJSauer @AnastasiaSMihai @biljana_parapid @Hragy jamanetwork.com/journals/jamac…

Regular aspirin use and reduced risk of aortic valve calcium and severe aortic stenosis in individuals with elevated lipoprotein(a) levels! ow.ly/l9mW50YljMj #EHJ #cardiotwitter #aspirin #aortic #stenosis #lipoprotein(a) @ESC_journals @escardio

@AlexRazavi @seamuswhelton @MichaelJBlaha @WendyPost9 @CiccaroneCenter @hopkinsheart

🆕 Effect of mavacamten on sudden cardiac death risk scores in obstructive hypertrophic cardiomyopathy 💡 see @ESCHeartFailure ow.ly/hKiC50YmgGF @EJHFEiC @JanBiegus @Ppponikowski #HFA_ESC @hvanspall @ShelleyZieroth @FudimMarat @gcfmd @AlexMebazaa @MarcoMetra @GianluSava

🫀 In HCM, combining imaging biomarkers improves risk prediction! High LGE% + low LV-GLS ➡️ highest risk of CV events, including sudden cardiac death. Integrating structure & function aids precision stratification 🔬 jacc.org/doi/10.1016/j.… #JACCAsia #cvHCM #RiskStratification

NEW: A study of more than 46,000 patients with #AtrialFibrillation taking the blood thinners apixaban or rivaroxaban found that those who were also prescribed diltiazem had a higher risk of serious bleeding than those prescribed metoprolol. bit.ly/40zVay1 @DawwasGhadeer @VUMCDiscoveries

Elevated Lp(a) increases the risk of abdominal aortic aneurysm (AAA), independent of #ApoB. Using UK Biobank & genetic analyses, Sharma et al. in #JACCBTS provide evidence that supports Lp(a) as a causal risk factor & potential therapeutic target for AAA. jacc.org/doi/10.1016/j.…

Lipoprotein(a)-lowering therapies: a promising future. A state-of-the-Art review in #EHJ 👉 ow.ly/V6Rm50YlK3J @RoccoMontone @ehj_ed

Very high lipoprotein(a) levels are associated with increased 30-year risk of major #cardiovascular events, coronary heart disease, ischemic #stroke, and cardiovascular death among healthy women. ja.ma/4tO1644

Important paper led by Head Coach @MichaelJBlaha - the MJ23 of Prevention - & his all-star team on the globalCV impact of severe obesity on CVA, AF, & total CVD @ZeinaDardari @CiccaroneCenter @hopkinsheart

Scientists gave 20 Alzheimer's patients creatine monohydrate for 8 weeks. This was the first clinical trial to test creatine in humans with Alzheimer's. What happened to their memory and cognition was extraordinary. Here's how remarkable creatine can be for your brain:

#EHJIMP 🫀 Mitochondrial cardiomyopathy is a cause of #LVH to keep in mind‼️ 🫀Cardiac involvement in mitochondrial diseases is common (⅓), including #HCM, conduction disease, #WPW and #DCM. #whyCMR aids in the differential diagnosis! ⏩Read more doi.org/10.1093/ehjimp…

🧵 1/ First ever AHA/ACC/multi-society guidelines re: diagnosis & management of acute PE released today! 2 year effort with 38 authors from 10 specialties. Link attached & summary in this thread: jacc.org/doi/10.1016/j.…

In a population-based cohort, third-trimester levels of soluble fms-like tyrosine kinase-1 (sFlt-1) and high-sensitivity cardiac troponin I were independently associated with greater long-term #CardiovascularDisease risk in pregnant women. ja.ma/46itQYz