Benjamin S. Simpson

So @nanopore discovered something a few days ago - and it has to do with light. And they posted this image (sorry, too good not to share off the community). Yes, that’s 469% increased output. So, we decided to give it a shot and …

Pleased to share latest study from our lab, led by @LukeSimpsn and in collab with the Nichols Lab. biorxiv.org/content/10.110… .

Mellon repository is available at github.com/settylab/mellon, and the pipeline for primed and lineage-specific peak identification (along with other utilities for ATAC metacells) is available at: github.com/settylab/atac_…

Check out our new study in @ScienceMagazine, where we take on a 100-year-old debate: what’s the role of aneuploidy in cancer? We discovered that genetically removing extra chromosomes blocks cancer growth - a phenomenon we call “aneuploidy addiction”. science.org/doi/10.1126/sc…

Delighted to see this work, led by @Lukesimpsn, and a tribute to our late friend Andrew Johnson, published in #PLOSBiology: NANOG is required to establish the competence for germ-layer differentiation in the basal tetra ... dx.plos.org/10.1371/journa… @mattloose

Excited to share our latest work out now in @CD_AACR, a high-resolution insight into how advanced metastatic melanoma evolves as it colonizes various sites in the body. Huge thanks to everyone involved (patients, authors, funders, reviewers etc) aacrjournals.org/cancerdiscover…

We are hiring!! We are looking for talented postdocs experts in cancer immunology, molecular biology/antibody engineering to join ⁦@QuezadaLab⁩ ⁦⁦@CRUKCOLcentre⁩ and the team that will make the next gen immune modulatory agents for cancer. ucl.ac.uk/work-at-ucl/se…

Very proud to see part 1 of the work led by the late Andrew Johnson finally out. Thanks @LukeSimpsn and @mattloose for the great work. #evolution #pluripotency #nanog biorxiv.org/content/10.110…

Have you ever needed to automate #PowerPoint in #R? Well you're in luck! I wrote a tutorial on it. Enjoy! Article: buff.ly/3bsRloG #rstats

@TheWhitakerlab @MrJosephNorris Well done team!

And another!! Congratulations again to everyone involved @MrJosephNorris @b3nsimp #MRI #ProstateCancer #PSMA #cancerresearch mdpi.com/2072-6694/14/1…

🔥Elated to share that I'm amongst the scientists🔬announcing the award of a UKRI Future Leaders Fellowship🏆 Our mission🧗 •Use the immune system to prevent cancer by asking when+how recognition&regulation first occur. #ukriflf @uclcancer @UKRI_News @uclnews @CRUKLungCentre

🎉🎉 Extremely proud and grateful that our Tissue Immune Cell Atlas is out in @ScienceMagazine bit.ly/Sci_abl5197 A thread 🧵 (1/12)

Researchers have identified a new and unexpected kind of cell division that occurs without DNA being replicated

How does a skin cell become melanoma? We built one to find out, to help understand this lethal disease. science.org/doi/10.1126/sc… @ScienceMagazine W/ co-1st @ele_tt, @johnkwon71, & senior author Aviv Regev. Early years joint w/ @LeviAGarraway. And many others in last tweet! 🧵 1/18

Small but mighty! This is a video of a killer T cell of the immune system destroying a monstrous ovarian cancer cell. I recently captured this data on a spinning disc confocal microscope.

Sometimes the mental energy for complicated pipes with xargs just isn't there, and you simply need to get the job done. This is where multiple cursors in Sublime Text (or VSCode) comes in to play: #Bioinformatics #Programming #DataScience

Preclinical study suggests that AR blockade sensitizes prostate cancer to ICIs by directly enhancing CD8+ T cell function. Mechanistically, AR was found to bind to the IFNγ gene & thus suppress cytokine production in CD8+ T cells. nature.com/articles/s4158… #PCSM #ImmunoOnc

🔥🔥 ONLINE NOW @NatureCancer: "The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response", by @IdoAmitLab @MiriamMerad #AmosTanay & Co Find it here! go.nature.com/35nKOsq rdcu.be/cIaAQ

No more shift key when writing long path names on the cluster! Turn on case-insensitive autocompletion for BASH: askubuntu.com/questions/8706…

Today we reported our Q4 and year-end 2021 financial results and business highlights, including clinical data demonstrating the unique ability of our T cell platform to detect, quantify and track our clonal neoantigen-reactive T cells. View here: ir.achillestx.com/news-releases/… $ACHL