@AndrewGSugrue @joshim5 @AndrewGSugrue the quality of your research, conviction, and founder-orientation are second to none. Thank you for being such amazing partners.
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Jack Dent
114 posts
When we first invested in Chai’s Series A, we were drawn to the audacity and the ambition of @jackdent and @joshim5 who envisioned a future of AI one-shotting novel drug candidates. Fast forward just a year and a half later and that vision is becoming reality with some of the largest pharma companies in the world. While AI’s impact in enterprise will create winners and losers, in biology and healthcare, all of humanity will benefit from more cures and better treatments thanks to the hard work and vision of teams like @chaidiscovery. Excited to have friends like @mamoonha and @lachygroom on this journey with us.
businesswire.com/news/home/2026…
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@zavaindar @joshim5 @chaidiscovery We are honoured to have been partnered with you from the very start, and even more honoured to have you as a lead check in this round.
@_DimensionCap sets a new standard for VCs.
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a few years ago we office’d @joshim5 @jackdent and the early @chaidiscovery team in our noho hq as they traversed the 0 to 1 of newco genesis. alongside thrive and OAI we led the first financing into the company
today, as CHAI sets the bar for generative molecular design - inking partnerships with Lilly, Pfizer, and Novartis - @_DimensionCap is writing the largest check to date in our 3 year history, helping to lead a $400M financing with index, kleiner, and sequoia
at the limit, preclinical (and increasingly clinical) drug discovery and development will never be the same 🚀
Zavain Dar@zavaindar
Today we’re launching @chaidiscovery, led by @joshim5 & his polymathic world class cofounders. We’re also open sourcing Chai-1: a state of the art frontier model for biomolecular interactions. @_DimensionCap has co-led the founding round alongside Thrive & OpenAI
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Don’t get distracted by the doomers, AI is going to create jobs and drugs to cure disease. Congrats to Chai team.
Jack Dent@jackdent
Thrilled to announce our $400M Series C led by @IndexVentures, with @kleinerperkins, @sequoia, @_DimensionCap and others. Great to speak to @m_delamerced @nytimes about how drug discovery using AI is moving from a promise to actual deployment.
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Thrilled to announce our $400M Series C led by @IndexVentures, with @kleinerperkins, @sequoia, @_DimensionCap and others.
Great to speak to @m_delamerced @nytimes about how drug discovery using AI is moving from a promise to actual deployment.
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Jack Dent@jackdent
Chai’s year of deployment continues. Great to announce this collaboration with @Novartis today to support multiple therapeutic programs with our models, including Chai-3. It’s been incredibly rewarding to collaborate over the past year. Looking forward to expanding our work together.
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Chai’s year of deployment continues.
Great to announce this collaboration with @Novartis today to support multiple therapeutic programs with our models, including Chai-3.
It’s been incredibly rewarding to collaborate over the past year. Looking forward to expanding our work together.
Joshua Meier@joshim5
I'm delighted to announce a new collaboration between @ChaiDiscovery & @Novartis. It's been a pleasure working together over the past year, and we're excited to scale our collaboration to support broader deployment of Chai-3 across multiple therapeutic programs.
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I’m so excited to share this update on @Conception –
We’ve generated the first early human eggs derived from stem cells.
This is a big deal -- the potential to redefine fertility is real.
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Better data ~> smarter models. Congrats to @ninklefitz and team!
Nicole Fitzgerald@ninklefitz
I've started a new company called @tacitlabsco, an applied research lab at the intersection of AI and biology. 1/n
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AI drug discovery has progressed from idea/open source to use at the largest pharma companies in the world in 2 years. What felt uncertain at seed seems inevitable today. Huge AI + bio acceleration. @chaidiscovery crushing on the commercial front!
Jack Dent@jackdent
I’m delighted to announce @chaidiscovery's collaboration with @pfizer. Their scientists will deploy our AI platform to accelerate drug discovery, including early access to our latest frontier model Chai-3. You can learn more about this partnership and our momentum in @amyfeldman's feature in @Forbes out today forbes.com/sites/amyfeldm…
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Huge - congrats @jackdent and @chaidiscovery
Jack Dent@jackdent
I’m delighted to announce @chaidiscovery's collaboration with @pfizer. Their scientists will deploy our AI platform to accelerate drug discovery, including early access to our latest frontier model Chai-3. You can learn more about this partnership and our momentum in @amyfeldman's feature in @Forbes out today forbes.com/sites/amyfeldm…
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I’m delighted to announce @chaidiscovery's collaboration with @pfizer. Their scientists will deploy our AI platform to accelerate drug discovery, including early access to our latest frontier model Chai-3.
You can learn more about this partnership and our momentum in @amyfeldman's feature in @Forbes out today
forbes.com/sites/amyfeldm…
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The aging research will continue. Thank you @foundersfund for leading, @ThriveCapital, @Greenoaks and @QuietCapital for joining and all our insiders for coming back.
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Fun to sit down with my friend @SabrinaHalper and talk about Chai's journey. Thanks for having me on!
Sabrina Halper@SabrinaHalper
"We have this long term vision of turning biology from something which is trial and error and experimental and make it something that looks more like an engineering discipline in the next century." New Episode with @jackdent ! 0:00 Intro 02:28 Inside @stripe w/ @patrickc, at <100 People 08:45 @sama role in @chaidiscovery origin 16:20 Chai-2 Antibody Breakthrough 19:24 Approaching biology as an engineering problem 24:45 Using AI models to treat people on an individual scale 26:52 Robotics in labs 27:22 Pharma industry today 29:49 The clinical trial bottleneck 32:53 Personalized biology models & cancer vaccines 36:24 Longevity, peptides, and trillion-dollar drugs 39:02 Does it matter that the government cut exploratory science grants? 41:00 What next-gen Chai models will do 42:08 Can frontier AI labs build this themselves? 43:26 Biology is hard
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WSJ features @Neo as one of the highest performing VC funds of the decade.
Thank you for the in-depth feature, Yuliya!
Yuliya Chernova@ychernova
Scoop on fund returns for @apartovi's Neo. Neo's 2018 Fund 1 is at 7.5X, its 2021 Fund 2 is at 6.5X net. There's a widening gap between high performers and everyone else in VC now. More on how Neo did it: wsj.com/pro/venture-ca…
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Today we’re announcing $80M in new financing for @appliedcompute, to help enterprises go from general to specific intelligence.
Our view is that the winners of this era will be the companies that turn their information, and expertise into intelligent systems that compound over time. They’ll have agents that get sharper every week by learning from real decisions, outcomes, and feedback.
Applied Compute@appliedcompute
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First in Human! When @rhomsany and I first started Octant, this was the dream. A platform that makes molecules that few others can go after… to get the chance to tackle severe diseases with poor to no standard of care. It's been a long journey but so incredibly proud of the team and thankful to the volunteers who make this attempt possible. We got to celebrate with these new sunhats! octant.bio/news/octant-an…
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Jack Dent retweetledi
Memo: What If We're Right?
We recently wrote a private letter to partners & friends of a common failure mode: the inability to consistently reason through the daisy chain of downstream consequence when non-consensus, low-probability, events actually occur
pages: 1-3
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