Jonathan Courtney
5.8K posts

Jonathan Courtney
@Jicecream
Founder/CEO of https://t.co/V2Mb0IZ0Ij, https://t.co/iacgr9HU2m and host of The Unscheduled CEO podcast https://t.co/Y62TwHNdqz . I do not know what I’m talking about.






I have finished reviewing/getting impressions of every single game out of the 945 games submitted to #vibejam. If you submitted a game and haven't received any feedback or tags from me, take a look at the link below. Impressions tend to be brief. To be frank, some of these games did not deserve even the brief time I put into them. But SOME of these games are genuinely stunners. Some of these games have enormous depth, gorgeous visuals, addicting loops, and genuine commercial potential. I'll be posting some of my thoughts, opinions, and wrapup ideas as the official judging of the vibejam continues. As a reminder, I am not an official vibejam judge. I just wanted to look at all of the competition and see what the playing field looks like.






Stopped wearing AirPods while grocery shopping because it’s antisocial, doesn’t matter if everyone else is doing it, you have to start with yourself.



Researchers have identified a consistent chemical difference in the brains of people with anxiety disorders: significantly lower levels of choline-containing compounds. A groundbreaking 2025 meta-analysis by UC Davis Health scientists revealed this biological marker through proton magnetic resonance spectroscopy (1H-MRS) data. The study found an average 8% reduction in total choline (tCho) in the prefrontal cortex, a key region for emotional regulation, decision-making, and cognitive control, as well as across broader cortical areas. Analyzing 25 datasets involving 370 individuals with anxiety disorders (including generalized anxiety disorder, panic disorder, and social anxiety disorder) and 342 healthy controls, the researchers documented this reduction as a transdiagnostic feature consistent across different anxiety conditions. This represents the first meta-analysis to identify a reliable chemical pattern in the brains of people with anxiety, pointing to measurable neurochemical alterations rather than purely psychological factors. Choline, an essential nutrient obtained from foods such as eggs, salmon, and soybeans, plays a vital role in brain cell membrane integrity and neurotransmitter synthesis. The authors suggest that heightened arousal and chronic stress in anxiety disorders may increase choline demand, depleting levels faster than dietary intake can replenish them and potentially impairing the brain’s ability to regulate the fight-or-flight response. While the findings open promising avenues for nutritional interventions, experts stress that dietary or supplemental approaches should complement, not replace, established treatments. [Maddock RJ, Smucny J. Transdiagnostic reduction in cortical choline-containing compounds in anxiety disorders: a 1H-magnetic resonance spectroscopy meta-analysis. Molecular Psychiatry. 2025. DOI: 10.1038/s41380-025-03206-7]


@pbertrand_dev @levelsio Yeah fair point. I agree the grants shouldn't be the goal, but given the astronomical taxes we pay, might as well try to cop some back (IME, at least in Italy, it's quite rigged unfortunately 😁 and there's even companies that specialize in helping you get these grants)







It’s amusing watching channels like these seem unstoppable with massive followings, only to crash back down. Ali Abdaal is another example of audience seasonality mixed with getting trapped in a topical loop. Notices that the algorithm stops rewarding “more of the same,” and viewers mature out of the phase that attracted them so the creator either evolves or slowly becomes a parody of their own niche.







