Changfeng Chen
251 posts
Changfeng Chen
@long_wind98
PhD student @WashUdbbs in Molecular Cell Biology | Alum @PKU1898 (he/him)
Did you know there are lots of similarities between the innate immune systems of animals/plants and the phage defense systems in bacteria? Check out our new study by the amazing trio Alex (Linyi) Gao, @maxewilkinson, and @thestrecker. Congratulations! science.org/doi/abs/10.112….
A @Nature study from Rockefeller's @junyue_cao describes a new platform called PerturbFate that reveals how diverse genetic perturbations funnel into shared disease states, a method that could unlock therapeutic targets for complex diseases. 🔗: bit.ly/4thIsRw
Chris Paul and his leadership style clashed with the Clippers, sources tell ESPN. Paul has been vocal in holding management, coaches and players accountable, which the team felt became disruptive. Specifically: Ty Lue was not on speaking terms with Paul for several weeks.
.@FeiyaOu1 & Kenneth Murphy discuss study by Sun et al @gardnerlabucsf (hubs.la/Q03mLNtM0) highlighting eTACs as a key component of the RORγt+ antigen-presenting cells acting in the induction of RORγt+ pTregs specific to food antigens: hubs.la/Q03mLP340
I'm thrilled to share our new #bioRxiv preprint from @junyue_cao lab at @RockefellerUniv! We present PerturbFate, a high-throughput single-cell CRISPR platform profiling nascent/pre-existing RNA, steady-state RNA & chromatin accessibility. biorxiv.org/content/10.110…
Congratulations to Zhijian “James” Chen, 2024 #LaskerAward winner! – “for the discovery of the cGAS enzyme that senses foreign and self DNA, solving the mystery of how DNA stimulates immune and inflammatory responses.” laskerfoundation.org/winners/cgas-e… #Lasker2024 #LaskerLaureate
Let me introduce: InstanSeg 🦠🔬💻👩🔬 This *would* have been a short thread about Thibaut Goldsborough’s PhD work… but he solved too many problems. Now it's a long thread about 2 preprints, a whole new approach to cell segmentation & #opensource software to make it easy to use