MET-FIT Lab

In the second episode of the #MeetThePI series, @Debojyoti_C shares his personal journey in science so far and reflects on the people and experiences that have shaped his path. He also talks about his team at @IGIBSocial and offers insights into his research. @SouvikM29933298 @CSIR_IND @CSIR_HRDG Watch here:youtu.be/hEwpjJlNy60

Paper Cuts #3 | JC by Poorva Featuring Patel et al., Nature (2026): Ageing promotes metastasis via activation of the integrated stress response. Ageing suppresses primary tumour growth but promotes metastasis. nature.com/articles/s4158…

✨ Since January, our lab has begun an alternate‑weekly Journal Club series — presenting impactful papers and sharing short write‑ups in our own words. We’ll be posting every other week — snapshots of our discussions + reflections to follow!

Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance @CellCellPress cell.com/cell/fulltext/… @BoyiGan @MDAndersonNews

First approved CAR-T against solid tumor. Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer. thelancet.com/journals/lance…

Now online: Blockade of Tumor-Intrinsic TGFβ Signaling Drives Hyperprogression in Small Cell Lung Cancer doi.org/10.1158/2159-8…

CD4+ T cells impair tumor growth through IL-3 and TNF-dependent vascular damage @ScienceMagazine @NIH science.org/doi/10.1126/sc…

✨ Continuing our alternate-weekly Paper Cuts series ✨ 2nd Paper Cut of the year - JC by @amishaaab —featuring Cassandras et al., Nature (2026): “Glucocorticoid–FAS axis drives immune evasion in metastatic seeding.” 🔗 nature.com/articles/s4158…

First JC of the year was presented by @VermaPalavi99 on : "Critical role for a high-plasticity cell state in lung cancer'' and here is the link of the paper : nature.com/articles/s4158…

A new Science #Immunology study highlights an approach called Effero-seq, which shows that #efferocytosis of tumor cells in mouse models of melanoma can induce protumoral functions in #macrophages. @meravcohen8 scim.ag/4o95WpZ

A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma dlvr.it/TSzKxk

In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging dlvr.it/TSv1b2

"Mitochondria-lysosome coupling contributes to lysosome acidification and aging" Read more in MOlecular Cell: cell.com/molecular-cell… Chuankai Zhou & colleagues @molecularcell

Welcoming our first dissertation student @Akhil_3600 to the lab! Wishing you a journey filled with curiosity, growth, and discovery — and hoping to see your valuable contributions ahead.

#Review 🚨 Cancer cells dynamically rewire immune checkpoint expression across multiple layers. Understanding these mechanisms could unlock new biomarkers and improve immunotherapy outcomes. 📖👇 dlvr.it/TSlFhH

Yuki Honda Keith, Tri Giang Phan et al. @garvaninstitute show that tissue-resident CSF1R-dependent CD169⁺ #macrophages localize deep in the skin. They surround growing tumors and directly suppress #melanoma growth independent of T and B cells. hubs.la/Q04hDVgY0

🎥✨ Our PI shares her journey in Life of a PI — a story of science, leadership, and inspiration. Watch now on YouTube! youtu.be/DDsEvhkLgIM

“Beyond the science, we enjoyed moments of learning, collaboration, and fun — from poster sessions to networking and exploring new ideas.”

Our team (PR, RD and AB) showcased their work through posters, learned from peers, and enjoyed the vibrant exchange of knowledge. @amishaaab @Dubeylisation @pranavrana1999

🌍✨ Delighted to join the 26th International Pigment Cell Conference (IPCC 2026) / 7th PigmentoryCon. 🎤 Our PI @shruthy_suresh gave an inspiring talk, sparking meaningful conversations with the global pigment cell community. #IPCC2026