Siddharth Krishnan

Paper from the post doc on HSPCs in the healthy gingiva finally out in @JExpMed 👇🏽👇🏽👇🏽

Architecture of the neutrophil compartment @Nature nature.com/articles/s4158… @ivanbamartin @AndrsHidalgo16 @lai9uan @danielacerezo @Yale 🇨🇳🇪🇸🇺🇸

Inhibitory PD-1 axis maintains high-avidity stem-like CD8+ T cells @Nature #Germain @NIAIDNews nature.com/articles/s4158…

pDCs amplify tissue-resident memory CD8+ T cell responses during viral reinfection @JExpMed rupress.org/jem/article-ab…

Dynamics and variegation in the Treg response to IL-2 pnas.org/doi/10.1073/pn… @KumbaSeddu @Harvardmed

iPEX facilitates untargeted spatial proteomics at micrometer resolution for diverse applications @Nature @ZouYilong 🇨🇳 @Westlake_Uni nature.com/articles/s4158…

The Raman effect is the change in the wavelength of light that occurs when a light beam is deflected by molecules. It was named after Sir Chandrasekhara Venkata Raman who was born #OnThisDay, 7 November 1888. The Raman effect is used to analyse different types of material.

If only Rosalind Franklin had pre-printed her image

Amazing study by Anne and co. demonstrating the role of PU.1 in maintaining the microglia homeostatic state nature.com/articles/s4158…

Exciting new work from Anne Schaefer’s lab describing new protective microglia biology 👏👏👏 || Lymphoid gene expression supports neuroprotective microglia function | Nature nature.com/articles/s4158…

Ray, Krummel et al. show that targeting CD206⁺ #macrophages disrupts the establishment of a key antitumor immune axis. hubs.la/Q03RrVby0 📘 #cancer #immunotherapy collection: hubs.la/Q03RrZvk0 #SITC25

Online now: Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development dlvr.it/TP7k7c

Viral vectors displaying peptide-MHC are versatile tools for activating and reprogramming antitumor CD8 T cells directly in vivo @ScienceAdvances @MEBirnbaum @MITdeptofBE @kochinstitute @ragoninstitute science.org/doi/10.1126/sc…

Tertiary lymphoid structures in a subset of gliomas that show signs of functional adaptive immune activation and are associated with longer overall patient survival and an immune-permissive tumor microenvironment @ImmunityCP @K_Imkeller 🇩🇪 cell.com/immunity/fullt…

Balancing IL-17–mediated protection and IFN-γ–driven pathology at mucocutaneous barriers @TrendsImmuno cell.com/trends/immunol… @NIH 🇺🇸

AdFalci Vax — India’s 1st indigenous multi-stage malaria vaccine 💉🌍 developed by @ICMR_RMRCBBSR Licensed to industry partners under #PatentMitra . Innovation ➡️ Impact. @PanaceaBiotec @ZydusUniverse @biological_e @TechinventionL @indimmune_

The billionaires funding aging reversal. When they were young they wanted to be rich. When they were rich, they wanted to be young. @shaneshifflett @AmyDMarcus @AlexLJanin wsj.com/health/wellnes…

Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia | Science science.org/doi/10.1126/sc…

Our paper made the September cover of @NatImmunol! 🎉 Aren’t dendritic cells beautiful? 😍 SEM shows pDCs transitioning into cDC2-like cells. Huge congrats to the whole team! 👏 🔗 nature.com/ni/volumes/26/…

Supercharged NK cells: a unique population of NK cells capable of differentiating stem cells and lysis of MHC class I high differentiated tumors🇺🇸 nature.com/articles/s4141… important work from immigrant scientists 🇮🇳🇹🇼🇮🇷 @UCLA

Dietary saturated fatty acids skew monocytes and macrophages in the lungs toward an inflammatory phenotype and exacerbate airway inflammation in mice, shows a study that decrypts the connection between diet and lung immune cell activation. @ScienceTM scim.ag/46bjnOQ