@BowTiedHRT A friend I know tried reta for about two months, only about 1mg. Noticeably amped up her anxiety, went back to tirz...
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Van Dyke of the Deplorables
24.8K posts
Van Dyke of the Deplorables
@Picodegallows
Professional yeeter and amateur cynic. If you see me laughing, it's probably at something that's on fire or should be.
Outpost 1 เข้าร่วม Ocak 2016
711 กำลังติดตาม1.1K ผู้ติดตาม
It’s official, I don’t like Retatrutide, and damn, I wanted to.
I believe it to be one of the finest things to come out of the pharmaceutical laboratories since penicillin, but I won’t run it again anytime soon unless I decide to enter a monastery.
This is my third experiment with it. I’m about 3 1/2 weeks in, using 2 mg a week, injected once weekly. The first trial was daily administration of a microdose totaling 2.1 mg a week, and my second experiment was twice weekly administration at 1 mg.
I want the lipid support, the increased insulin sensitivity, and the increased nutrient partitioning, but I’m not willing to sacrifice my “desires” for the benefits.
Tirzepatide and Retatrutide do a really good job of turning off, or turning down the food noise for me. I’m admittedly a comfort eater. If I’m stressed, I can find some temporary solace in a bucket of Trader Joe’s chocolate chip dippers or a couple of fancy pizzas or both. Why not both? And some while I’m at it!
The Reta does a magnificent job of turning down the food noise, and I know it doesn’t do that at the little dose I’m using for everybody, but I can effortlessly eat like a committed professional bodybuilder when I’m running it. All I crave are my necessary macros, and it’s not hard to get them down, and I don’t suffer from any weird intestinal issues or bloating or nausea.
What I do notice, and what I really can’t reconcile myself to, is that it turns off not just the food noise, but it turns off my sex noise. It doesn’t kill my libido necessarily, but it turns my sexual desires into something that I can take or leave: I guess to put a finer point on it, it’s not that I’m not interested, it’s that I’m not interested in putting in the minimal effort into initiating sex. WTF? Who am I on this stuff??
It’s a fascinating compound. Not only does it turn off food noise and do all of the cool things that I mentioned above, but it also seems to turn off retail urges as well. I’m not a big spender, but I’ve always enjoyed looking through fancy catalogs and window shopping, and when I’m running a GLP class compound, I’m not even interested in looking in the window of a nice retail store.
I can certainly deal without the retail noise, however little it may be in my normal life, but I am absolutely unwilling to sacrifice my sex drive for any amount of aesthetic or lipid improvement.
I will leave it at this: I am jealous of those of you who can run the compound and keep your sex noise in place.
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@TudorCBogdan @CryptoMikli He suffers from depression, perhaps it's within that context.
"Drugs cured my depression" basically
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@CryptoMikli What does "resetting one as a human" mean?
Are we talking about "biological markers" reset, or "perceived reality" reset?
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Bryan Johnson reveals 5-MeO-DMT therapy outperformed every longevity protocol he’s tried
"If I compare my experience with 5-MeO to having a better diet, exercising every day, sleeping well, doing sauna, and hyperbaric oxygen therapy, this was more efficacious than all of them in terms of a reset of me as a human. It’s just incomparable"
"When you sleep well you feel great, when you exercise you feel great, but nothing compares to what 5-MeO did in terms of resetting me as a human"
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@living_energy The old rule is that chickens need a minimum of fourteen hours of light to lay eggs reliably in the winter, so most people run a lightbulb on a timer in the coop and extend daylight into the evening.
Peter is saying his infrared bulb worked even better than that.
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In 2006, I accidentally ran a red light experiment on my chickens.
We left town for Christmas during a cold spell and put them in the garage with a 250W red bulb from the feed store (the only bulb they had left).
Came back to an explosion of eggs. We'd used regular bulbs before to no effect.
I started shining it on myself while I worked. At first for the warmth, then as evening lighting because my eyes felt better. Soon my sleep improved. Found some obscure NASA wound-healing research on Google and a world of "cold lasers" and never looked back.
That was 20 years ago. Welcome to the party, Nature.
nature@Nature
A growing body of legitimate science has been exploring the benefits of red light therapy for several conditions, from ADHD, to retinal degeneration, to dermatology go.nature.com/3NoGcbx
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@birdabo Meta hasn't met a mind as twisted as mine.
They're best product will forever be FB marketplace.
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🚨Meta can now predict what your brain is thinking. read that again.
TRIBE v2 scans how the brain responds to anything we see or hear. movies, music, speech. it creates a digital twin of neural activity and predicts our brain’s reaction without scanning us.
trained on 500+ hours of fMRI data from 700+ people. works on people it’s never seen before. no retraining needed. 2-3x more accurate than anything before it.
they also open-sourced everything. model weights, code, paper, demo. all of it. free.
the stated goal is neuroscience research and disease diagnosis. the unstated implication is that Meta now has a fucking foundation model that understands how our brains react to content/targetted ads 💀
the company that sells our attention to advertisers just pulled out the psychology side of AI. we’re so cooked.
AI at Meta@AIatMeta
Today we're introducing TRIBE v2 (Trimodal Brain Encoder), a foundation model trained to predict how the human brain responds to almost any sight or sound. Building on our Algonauts 2025 award-winning architecture, TRIBE v2 draws on 500+ hours of fMRI recordings from 700+ people to create a digital twin of neural activity and enable zero-shot predictions for new subjects, languages, and tasks. Try the demo and learn more here: go.meta.me/tribe2
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@ShamarDBradley @TravelGov "We'll be right back with your phone, sir."
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@TravelGov At least they ask for it. In America, the govt just does it illegally and secretly
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Hong Kong: On March 23, 2026, the Hong Kong government changed the implementing rules relating to the National Security Law. It is now a criminal offense to refuse to give the Hong Kong police the passwords or decryption assistance to access all personal electronic devices including cellphones and laptops. This legal change applies to everyone, including U.S. citizens, in Hong Kong, arriving or just transiting Hong Kong International Airport. In addition, the Hong Kong government also has more authority to take and keep any personal devices, as evidence, that they claim are linked to national security offenses. Read more: hk.usconsulate.gov/security-alert…
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@Capt_Beef_Fart @paulsaladinomd Look up how most LEDs operate, which is pulse width modulation. They flicker different colors at up to 1khz to fill your eyes into seeing the color selected.
Now lookup all the clocks tied to circadian rhythm, non visual photo receptors, etc.
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@paulsaladinomd You fucking dumbass.
Incandescent light waste about 90% of their energy on heat. It’s shitty outdated technology.
LED lights can come in any light color spectrum and are often adjustable. You don’t have to make only cold blue light with them.
You’re a dangerous fucking hack.
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Why are you not doing this in your whole house?
LED flicker is horrible for the sympathetic nervous system.
The LED spectrum is mostly blue, zero infrared.
Incandescent lights cost a bit more but they provide meaningful "light nutrition." Get on this.
Ryan Dreyer 🪓@theryandreyer
Finally had enough of Big Light $25 bucks on Amazon and a return to soul
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@bryan_johnson This is the part where the drugs tell you to stop doing drugs.
How much is 30mg anyway? Is this a come to Jesus dose?
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One large psilocybin dose beat nicotine patches by 6x odds for smoking cessation.
82 otherwise-healthy cigarette smokers, 42 received a single high-dose 30mg/70kg psilocybin session, and 40 initiated an 8- to 10-week course of nicotine patch treatment.
At 6 months; participants were 6x more likely to achieve prolonged smoking abstinence. With biomarker proof.
Nicotine patch: 10% prolonged abstinence
Psilocybin: 40.5% prolonged abstinence
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@BozackDakilla @shiri_shh If I had fuck you money I'd use it to give someone I disliked insomnia.
Circadian rhythm baby
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@shiri_shh List 5 use cases where it would make sense to spend a “couple thousand dollars an hour” to light the outdoor space. 🤔
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@Gaurab Totally true… What’s your intuition on this? Heat seems to be the way, RF devices are promising to me, the same way they are promising for large bitumen in carbonate deposits. If we got it flowing with heat, flooding with the correct catalysts or miscible solvents could work
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The next oil boom will happen once we figure out how to extract from kerogens. The Green River Formation holds 4.285 trillion barrels of oil equivalent. That is more than 15 times Saudi Arabia's entire proven reserves. It is the largest hydrocarbon deposit on Earth, and the United States cannot produce a single commercial barrel from it. The reason nobody can crack it is molecular. Kerogen is not oil. It is a solid organic polymer locked inside rock, insoluble in every known solvent. Converting it requires pyrolysis above 300°C and returns barely more energy than it consumes. The energy return on energy invested sits around 1.5 to 1. Shell spent 30 years on this. They drilled heater wells and froze the surrounding groundwater into a containment wall to cook the rock underground. They quit in 2013. ExxonMobil tried running electricity through propped fractures to heat kerogen in place. They quit in 2015. Estonia has been surface-retorting oil shale since the 1920s and it works, but only at Estonian scale, on Estonian-grade ore with higher organic content than Green River. Every serious American attempt used brute-force heating and 2000s-era chemistry. Catalytic approaches to kerogen conversion have advanced since then, but nobody has gone back to try. The largest hydrocarbon deposit on Earth has been sitting untouched since 2015 because nobody can figure out how to get the oil out of marlstone.
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@BabakTaghvaee1 Yeah, that looks like a hell of a collision. Why were refuelers running racetracks in opposite directions ?
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BREAKING: This is the first video showing the wreckage of the KC-135R (RT) of the U.S. Air Force, which was shot down over Iraq on March 11, most likely by a Shahed-358 surface-to-air missile launched by Iraqi proxies of the IRGC Qods Force. This tragic incident has resulted in the death of six crew members of the aircraft.
#OperationEpicFury #OperationLionsRoar
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Trump doesn't seem worried about the midterms while everyone else is. It's obvious why.
He's got Maduro, Smartmatic/Dominion, Georgia, etc etc. Just tons of evidence he can roll out and then do things in the name of national security.
My guess: paper ballots only, ICE at polling stations, same day counting, and a bunch of politicians on both sides under indictment and not polling so hot.
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This is a very good post but I would like to add the huge thing that’s missing.
If Trump presents the evidence of foreign involvement in our elections, with help from democrats, it’s not a “high turnout” of republicans, that the democrats will fear.
It will then become a “national security” issue and treason.
That will give the president the Constitutional authority to transform the entire election system, in order to remove all the fraud.
It will also trigger mass arrests.
That’s what the democrats really fear.
Matt Morse@MattMorseTV
Some interesting information to keep in mind as we head towards midterms: —Redistricting: As a result of all of the recent redistricting following the 2024 election, Republicans are set to lock in ~12 new House seats, while the Democrats are set to lock in ~6 new seats. A Democrat-led redistricting effort in Virginia could give the Democrats another +4 seats, but the referendum to do so takes place on April 21 and actually might end up failing. Regardless, the Republicans are currently up ~6 seats in the House before anyone has even voted. —Supreme Court Rulings: The Supreme Court is expected to shut down the counting of mail-in ballots after election day, which has always mysteriously benefitted the Democrats (allegedly, this is one of their key mechanisms for voter fraud.) This is expected to be a 6-3 Supreme Court ruling in the very near future. The Supreme Court is also expected to determine that all of the Democrats racially gerrymandered voting districts across the country are unconstitutional - if the Supreme Court issues this ruling prior to early June, it will go into effect before the midterms and the Democrats will lose 12-20 seats in the House. Simply put, this is doomsday for the Democrats. —Legislation / Executive Order: If the SAVE America Act ends up getting passed, or an Executive Order clone of the SAVE America Act (one of these two things will happen 100% prior to midterms), the following things will be required to vote in midterms: proof of citizenship when registering, photo ID when voting, and mail-in voting will be entirely shut down outside of extreme exceptions (living overseas, disability, military, etc.) This would also be disproportionately catastrophic for the Democrat voter base. —Wild Card Variables: If Trump actually presents credible evidence to the American people that foreign influence has taken place in our elections and that the Democrats were complicit in this foreign influence (this is the allegation), you can imagine that Republican voter turnout would spike as a result. It’s somewhat likely that this will happen. You might have noticed - President Trump doesn't seem to be panicking about midterms right now, even though he'd be the single most-screwed person in the country if the Democrats were to retake the House. Maybe he has an ace up his sleeve, so to speak. ---Summary: It's going to be a VERY interesting year with LOTS of twists, turns, and suprises. Things are VERY FAR from being over.
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@BillboardChris This is fucking hilarious. Gonna watch this at least ten times.
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Trans-identified female lawyer berates judge, pulls trans card, gets found in contempt, resists arrest, screams “I can’t breathe,” and yells for people to call 911 as she’s fighting police.
Absolutely glorious performance.
Women should not take testosterone.
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@_Billdozer_ @DanTalks1 Hahaha the Han are the Borg
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Imagine a giant underground straw bringing water from faraway mountains to the dry desert. The swirly stone holes on top are like twisty funnels that catch the wind.
Whoosh—the wind spirals down and pushes the water along the hidden tunnels, like you blowing through a straw to move juice. No electricity needed!
It keeps farms green even today. Pretty smart, huh? 😊
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Everyone obsesses over whether aliens built the Nazca Lines, completely ignoring the true engineering miracle hiding right beneath them: a 1,500-year-old network of spiraling aerodynamic wind pumps that turned the world's driest desert into a permanent oasis.
Modern concrete crumbles after a few decades, yet 32 of these ancient, stone-lined subterranean aqueducts are still successfully irrigating Peruvian farms today.
If a pre-industrial society could engineer a self-sustaining desert water grid using nothing but rock, wood, and wind, what exactly is modern infrastructure's excuse?
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@DeseretStone Perfect age to be running after and tackling wayward illegals. Go get em
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People are so used to fatties and roided out lifters that normal-weight guys in their 20’s look like kids.
Most of history’s wars were fought by guys who looked like this and it would be a very serious mistake to underestimate their strength and speed.
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@BenjaminDEKR I stayed at a slightly rundown hotel last year that had an ATM style kiosk, which connected to an Indian who spoke good English.
It was a little unnerving but it was quick, and the machine can spit out replacement door keys.
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What is the point of hotel check-in desk people anymore?
Why isn't this 100% automated?
Verify your ID, pay, get entry code.
Why are humans still doing this?
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@grok @DRAINSWAMPSCUM @DD_Geopolitics @Lily81127145 Grok, I'm just warning you here, but you used 'credible reports' and Al Jazeera and Reuters in the same sentence. You should know better. Neither are credible, and both publish whatever they're told to by their masters.
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@DRAINSWAMPSCUM @DD_Geopolitics @Lily81127145 No, credible reports from Reuters, Al Jazeera, Rudaw, and Iraqi Defense Ministry attribute the Habbaniyah airstrikes to the US, targeting Iran-aligned PMF positions amid ongoing tensions and expulsion talks. No sources link Israel to this incident.
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🇺🇸💥🇮🇶 Americans, facing expulsion from Iraq, lash out at Iraqi Army
7 Iraqi soldiers killed, 13 wounded after U.S. strikes hit a clinic and engineering unit at Habbaniyah base in Anbar.
The base, shared by the Iraqi Army and PMF—officially part of Iraq’s security infrastructure—was struck twice on March 24–25.
Baghdad called it a blatant violation of sovereignty.
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@PoliceThePolic1 This kid might have superpowers. Maybe a real life Shazam. Perhaps he could be a control rod in a nuclear reactor. We should investigate. And that police department needs to start providing O, O, O, Ozempic.
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Local drunk jester discovers his true superpower: total taser immunity. Immediately sprints into the night like Batman and gone before cops can say ‘stop resisting.’
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@cirnosad Remember this? There were signs. Now it’s happening. Israel is done. Finished. 💀
Sprinter Press@SprinterPress
A raven was caught on camera tearing down an Israeli flag and throwing it on the ground
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By the way this is the worst possible omen at a civilisational level. It's still taken seriously back home in England and the Romans would stop entire wars over this sign.
It was interpreted as this: "the Gods have withdrawn their protection over this land".
Korobochka (コロボ) 🇦🇺✝️@cirnosad
The crows have circled and then left Tel Aviv. ⌛️✡️
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