Toni Petan

178 posts

Toni Petan

@PetanLab

Group leader @JSI_SLO and Associate Professor @MPS_JS #Lipids #LipidDroplets #CellBiology #Membranes #Ferroptosis #Metabolism

Jozef Stefan Institute Katılım Haziran 2012

320 Takip Edilen215 Takipçiler

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Toni Petan@PetanLab·2 Mar

Excited to share our new paper in @FEBSJournal! With @OndrejKuda & @FedorovaLab we show how LDs reshape the lipidome of PUFA-exposed cells & shift function within the same cell, revealing a context-dependent role in ferroptosis. Congrats Ana & @Lejaperne! shorturl.at/TyRl1

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Ferroptosis and Oxidative Stress@Ferroptosis_SP·4d

💥New Article in FOS! Ferroptosis surveillance: Insights from in vivo contexts by Dr. Thales Papagiannakopoulos @ThalesPapaG team and Dr. Jessalyn M. Ubellacker from @HarvardChanSPH Please check the link🔗: sciexplor.com/articles/fos.2… #ferroptosis #cell #scienceresearch

Ferroptosis and Oxidative Stress tweet media

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James Olzmann@OlzmannLab·6d

Thanks to @NatureSMB for publishing a "Research Briefing" on our recent work, highlighting the discoveries and providing context on the story behind our research into how vitamin B2 metabolism regulates FSP1 stability to suppress ferroptosis.

NatureStructMolBiol@NatureSMB

New online! FAD-dependent stabilization of FSP1 promotes ferroptosis resistance dlvr.it/TRSYqP

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James Olzmann@OlzmannLab·6d

1/3 Thrilled to see our paper led by Kirandeep Deol is out! We used CRISPR screens to uncover regulators of the ferroptosis suppressor FSP1. key discovery: vitamin B2 metabolism stabilizes FSP1 via FAD, revealing a new way vitamins regulate ferroptosis. nature.com/articles/s4159…

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Trends in Endocrinology & Metabolism@Trends_Endo_Met·7 Mar

Online Now: Targeting mitochondrial metabolism with combined metabolic activators dlvr.it/TRLrH5 #trends #endocrinology #metabolism

Trends in Endocrinology & Metabolism tweet media

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Ezequiel Dantas@eze_dantas·8 Mar

"Short-term fasting induces intratumoral accumulation of isoleucine, which reconfigures CD8+ T cell epigenetic programs and phospholipid remodeling, thereby licensing enhanced anti-tumor capacity."

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Toni Petan@PetanLab·2 Mar

@OlzmannLab Thanks, James!!

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James Olzmann@OlzmannLab·2 Mar

Very nice work on lipid droplets, FSP1, and ferroptosis in cancer cells from @PetanLab and colleagues. 👏 🤩

Toni Petan@PetanLab

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Toni Petan@PetanLab·2 Mar

@OlzmannLab @FEBSJournal @OndrejKuda @FedorovaLab @Lejaperne Thank you, James!!

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James Olzmann@OlzmannLab·2 Mar

@PetanLab @FEBSJournal @OndrejKuda @FedorovaLab @Lejaperne Great to see this exciting work published! Congrats @PetanLab and team! 🎉

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Toni Petan@PetanLab·2 Mar

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Toni Petan@PetanLab·2 Mar

@cohenlaboratory @FEBSJournal @OndrejKuda @FedorovaLab @Lejaperne Thank you, Sarah!

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Sarah Cohen@cohenlaboratory·2 Mar

@PetanLab @FEBSJournal @OndrejKuda @FedorovaLab @Lejaperne Congratulations, Toni! Looking forward to reading this 📖

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Sarah Cohen@cohenlaboratory·26 Şub

Amazing resource of CRISPR-based screens to identify regulators of #LipidDroplets in response to various metabolic and stress conditions

James Olzmann@OlzmannLab

2/ We used systematic, parallel CRISPR-based genetic screens in hepatocytes, run across multiple metabolic conditions, to identify regulators of lipid droplet biology. You can access these screens through crisprlipid.org.

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Toni Petan@PetanLab·26 Şub

@OlzmannLab @Nature @apsarruda @alymathiowetz @EmilyMeymand Congrats, James, Alyssa and team, nice to see this story published!!🎉🥳🍾

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James Olzmann@OlzmannLab·25 Şub

1/ Thrilled to share our new paper in @Nature: “CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.” From our lab together with @apsarruda, led by co–first authors @alymathiowetz and @EmilyMeymand. 🥳 nature.com/articles/s4158…

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Shannon Reilly@ShannonReilly5·23 Şub

Read my latest #research on #fat #metabolism and #thermogenesis, published with @SpringerNature in @NatMetabolism rdcu.be/e5gLi

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Cell Metabolism@Cell_Metabolism·18 Şub

New! Online now: Lipid droplet-induced T cell death sustains autoimmune tissue inflammation dlvr.it/TR28B9

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Sarah Cohen@cohenlaboratory·17 Şub

I'm delighted to present TWO new preprints from my lab, led by @MC_Zanellati and @ChihHsuanHsu1, about how #organelles remodel throughout #NeuronalDifferentiation. Check out the tweetorials about their papers below:

Sarah Cohen@cohenlaboratory

Cells come in many shapes and sizes, with diverse physiological functions. But how do #organelles and their interaction networks remodel during #differentiation of stem cells into different cell types? Here’s what we discovered about neuronal differentiation: 1/13

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EMBL Events@EMBLEvents·27 Oca

2026 has just begun and we are looking forward to welcoming you to EMBL for another year of groundbreaking science. Our programme now features even more events, check it out ➡️ s.embl.org/2026-poster

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Abdou Rachid Thiam@Rachid_Thiam·23 Oca

New preprint from the lab! Triglycerides act like salt on ice: they solubilize cholesterol esters and drive lipid droplet growth. The TG/CE ratio shapes both droplet size and proteome, mirroring lipoprotein organization. biorxiv.org/content/10.648…

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Greg Fairn@gfairn·20 Ara

New training awards for international applicants. We have spaces in my lab in Halifax, Nova Scotia and several projects available. Salmonella, Crohn's disease, lipid droplets, cancer biology, and my favourite PIPs. Have a look and email me if interested. nserc-crsng.canada.ca/en/news/launch…

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Toni Petan@PetanLab·19 Oca

@HenneLab @cohenlaboratory @NatRevMCB Congrats, Mike & Sarah! Can’t wait to read this👍🏼🏆

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Henne_Lab@HenneLab·16 Oca

With so many great reviews on LDs already out, do we need another? Sarah @cohenlaboratory & I were approached by @NatRevMCB to organize a review on LD heterogeneity and inter-organelle contacts...topics often in reviews, but not a focus. Fun project! nature.com/articles/s4158…

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Sarah Cohen@cohenlaboratory·16 Oca

Such a pleasure to write this review on #LipidDroplet heterogeneity, dynamics and organelle interactions with Mike @HenneLab! Thank you to the editorial team @NatRevMCB and to @YoniMalis for assistance with draft illustrations

Nature Reviews Molecular Cell Biology@NatRevMCB

New Online! Heterogeneity, dynamics and organelle interactions of lipid droplets dlvr.it/TQMlT6

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Keşfet

@ThalesPapaG @HarvardChanSPH @NatureSMB @OlzmannLab @FEBSJournal @OndrejKuda @FedorovaLab @Lejaperne