Benthos Prime Central

Explore how we turn complex data into actionable insights. 🌐mybenthos.com Led by @Prabhu_gene #BenthosPrimeCentral #MultiOmics #ExosomeResearch #PrecisionMedicine #DataDrivenBiology

🚨 2 days left! 🧬 Decoding #GWAS Variants: From Signals to Function 💡 Turn GWAS peaks into biological insight with #CRISPR, iPSC & functional #genomics. 📅 July 2 | 12 PM ET 🎙️ @rovingscientist 🔗 Register: us06web.zoom.us/webinar/regist… Powered by @mybenthos

🧬 GWASmeRNA™ Live Experience Hosted by @mybenthos Decode RNA-genomic connections & uncover how SNPs may act via RNA—not just DNA/proteins. 📅 June 25 (11 AM CET🇪🇺) 📅 June 26 (2 PM ET🇺🇸) 👇 Details & registration in the thread #GWAS #Epitranscriptomics #RNAtools

🧬 Scientific consulting that actually moves your science forward. At @mybenthos, we’ve worked with labs, startups & R&D teams across the globe. Sometimes you don’t need another experiment — you need a second brain.

Check out the latest review in the June 6th issue of @CircRes by Orlowski & colleagues "Intracellular #pH Regulation in Ventricular Myocytes: Implications for #Cardiac Health and Disease" at ahajrnls.org/4kaf2zv

🚨 Exercise is no longer optional, it is essential! One of the most impactful studies at #ASCO25 🏃‍♂️ The #CHALLENGE trial (LBA4319) proves that structured exercise after chemo in stage III colon cancer is not just lifestyle—it’s life-saving. 📊 5y DFS: 80.3% vs 73.9% ❤️ 8y OS: 90.3% vs 83.2% 📉 Mortality risk ↓ by 37% 📄 Simultaneously in @NEJM nejm.org/doi/full/10.10… #ColorectalCancer #OncoTwitter #ExerciseOncology #exercise

If you're following AI-driven drug discovery, you should read this paper below. Generative AI just advanced a first-in-class TNIK blocker for pulmonary fibrosis, rentosertib, through phase 2a.

Today in @ScienceMagazine we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with @SternbergLab. 1/13 drive.google.com/file/d/1I-UbCR…

Postdoc positions available in my lab @karolinskainst - exciting science and fantastic environment. I take mentoring seriously - 7/7 postdocs that left my lab has faculty positions today. Existing datasets and funds to build new ones available. shorturl.at/sj2YE

🚨 Wow! #ASCO25 @ASCO was absolutely massive! 10 @NEJM papers published simultaneously 👉 all practice-changing studies ! 🔬✨🧵 See below for these studies 👇@oncoalert

🚨 Hot off the press in Nature Communications! Engineered extracellular vesicles (EVs) achieve >40% genome editing in hippocampal cells after a single dose 🤯 🔗 nature.com/articles/s4146… 👏 Huge congrats to @Samir_ELA_lab & team!

🔬🧬 New expansion in situ genome sequencing uses #SuperResolution expansion #Microscopy #ExM to localize genomic DNA and nuclear proteins, applied to linking lamin abnormalities in progeria-derived fibroblasts with areas of aberrant chromatin repression: bit.ly/4kHjDJP

Don’t forget to tune TOMORROW, Tuesday, June 3 at 3 PM EST to hear Armon Sharei, PhD from Portal Bio “A Silicon Membrane-based Platform for Multiplexed RNA Delivery and Cell Engineering of Primary Cells” To register click this link: qrco.de/bfzCj3 #RNA #RNAMedicine

🧠 Huge leap in spatial genomics! gsMap by @liyang_song & @jyang1981 maps complex traits like schizophrenia onto the brain's spatial cell structureusing ST + GWAS. Must-read: nature.com/articles/s4158… #Genomics #SpatialOmics

What if #RNAstructure mattered more than sequence? That shift is here — in RNA therapeutics, folding, accessibility & mods like m⁶A are shaping smarter design. We’re building tools to make that possible. Is RNA structure underused in drug design?

Nature research paper: Programmable control of spatial transcriptome in live cells and neurons go.nature.com/44JXqpW

Mechanisms through which synonymous mutations can affect gene expression Zhang & Qian Nat Rev Gen nature.com/articles/s4157…

@CircRes Compendium on Interorgan Crosstalk in #HeartFailure and #Cardiometabolic Diseases Liao et al Research Letter "Heart-Brain Crosstalk in #MI: Role of Heart #EVs in Neuroinflammation" ahajrnls.org/3Slq7lO @MarbanLab @JankauskasPhD

Revoking J1 visas is not only cruel, it undermines trust in American science. As we wrote with Jan Vilcek, an immigrant whose work led to one of medicine’s biggest breakthroughs, J1 students fuel discovery, innovation & US economic growth. cell.com/cell/fulltext/…

We are hiring! The Ardehali lab at @UAZHeart and @UAZMedTucson is hiring postdocs and technicians. Our research focuses on metabolism, Immunology, iron biology and cardiovascular disease. Interested applicants can contact me directly.

🚨Tomorrow!🚨 Join us to hear Dr. Peinado (@hps2002) and learn about how tumour-derived sEVs shape the pre-metastatic niche and their potential as biomarkers and therapeutic targets. 🕒TimeZone: notime.zone/OQZd2vgr6C5M8 🎯Join the SNEV network: isev.org/membership