Peter Chockley

94 posts

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Peter Chockley

Peter Chockley

@PeterChockley

Natural Killer Cells and synthetic receptors. Assistant Professor at The Ohio State University. opinions=mine

Memphis, TN Katılım Temmuz 2021
164 Takip Edilen131 Takipçiler
Peter Chockley retweetledi
Malcolm Sim
Malcolm Sim@mjwsim·
The Sim lab has been hard at work and we’re proud to present our first paper. We developed new methods to study peptide:KIR interactions. Congratulations to star postdoc Tanusya Murali who led the project. biorxiv.org/content/10.648…
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Paul G Thomas
Paul G Thomas@PGTimmune·
After many rewarding years at @StJudeResearch surrounded by exceptional colleagues & groundbreaking science, I’m delighted to join @fredhutch to push boundaries in viral & cancer immunology. Grateful to St. Jude and looking forward to what’s next at FH! More about the move below
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Peter Chockley retweetledi
The Jeremy Chase Crawford Lab
I’m hiring a sr. bioinformatics research scientist in integrative analysis to perform data analysis and visualization, statistical analysis, experimental design, database development, mathematical modeling, and novel method development. Join the team. tinyurl.com/39fz6cwy
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Peter Chockley retweetledi
The Jeremy Chase Crawford Lab
Come join my lab as a sr. scientist focused on applied integrative biology to develop and implement novel technical approaches for assaying single cell dynamics, high throughput functional screening, and high parameter molecular phenotyping. tinyurl.com/3466kx8u #NowHiring
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Peter Chockley retweetledi
David J Glass MD
David J Glass MD@davidjglassMD·
RNAseq is commonly performed. We compared N=30 wild-type Bl6 mice to an N=30 heterozygotic knockout with a phenotype, and then downsized. We found you need at least an N= 8-12 to avoid a >50% false positive rate. A 2nd line confirmed the finding. biorxiv.org/content/10.110…
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Peter Chockley retweetledi
Nature Biotechnology
Nature Biotechnology@NatureBiotech·
In vivo AAV–SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy go.nature.com/4cfyac2
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Peter Chockley
Peter Chockley@PeterChockley·
@jkagan1 Totally agree. 6week vs 8week old mouse can dictate tumor growth or rejection. I rarely accept a 5 week old mouse study as mildly relevant scientifically.
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Jonathan Kagan
Jonathan Kagan@jkagan1·
So much of our knowledge of immunity is based on studies in young mice. Yet we know that the immune system changes as we age. How many rules of immunity are age-dependent? Are any rules age agnostic?
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Klebanoff_Lab
Klebanoff_Lab@KlebanoffLab·
🚨Pre-print alert: Here, we show that CAR-T *and* CAR-NK persistence is negatively self-regulated through activation dependent FAS ligand expression. Further highlights FAS as an actionable molecule to enhance cell therapies. @parkerici @MSKCancerCenter biorxiv.org/content/10.110…
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