Jie Gao

Thanks to everyone who joined the In Silico to In Vitro Hackathon with @adaptyvbio yesterday - we had a blast. Huge thanks to our sponsors @OpenRouter, @modal, and @RowanSci. We will share the results from Adaptyv as soon as they’re in (~3 weeks).

Come check out what we've built in the past month and hack with us :)

@paper Hey Paper team! Epic tool, I've been using it all day today - though is there something happening with the server? Currently having trouble reconnecting to server (on and off for a few sessions now)

Announcing Paper Desktop + MCP Now any agent can read or write with Paper Paper is connected. To your code. To your agents. To your data. To your teammates. Download Paper Desktop at paper.design

In Silico to In Vitro is our most ambitious hackathon yet. We’re teaming up with @adaptyvbio to run a challenge where scientists generate novel binders in silico, with top designs built and tested in the lab. Join us if you're in SF on 2/28: luma.com/a6t92ohv Co-sponsored by @RowanSci, @openrouter and @modal, with generous compute support.

The word around Silicon Valley is that everyone from Meta to OpenAI to xAI wants a piece of OpenClaw and its creator. Zuck and Sam might even have met with him. Ideally given its open source ethos he should take a cue from WordPress and build this one for the future for everyone, and go work with/at a company that would believe in that open source ideology.

@KexinHuang5 @a16z @MenloVentures @AnthropicAI Congrats Kexin! Beautiful branding :)

Today we’re launching Phylo, a research lab studying agentic biology, backed by a $13.5M seed round co-led by @a16z and @MenloVentures / Anthology Fund @AnthropicAI. We’re also introducing a research preview of Biomni Lab, the first Integrated Biology Environment (IBE), where we’re imagining a new way biologists work. Biomni Lab uses agents to orchestrate hundreds of biological databases, software tools, molecular AI models, expert workflows, and even external research services in one workspace, supporting research end-to-end from question to experiment to result. Agents handle the mechanics, while you define the question, then review, steer, and decide. Scientists end up spending more time on science: asking questions, understanding mechanisms, and eliminating diseases. Phylo (@phylo_bio) is a spin-out of @ProjectBiomni, where we will maintain the open-source community and push open-science research. I’m grateful to continue building with my co-founders @YuanhaoQ @jure @lecong and the dream founding team @serena2z @TianweiShe @huangzixin20151 @gm2123 @margaretwhua @malayhgandhi. We’re also fortunate to be advised by leading scientists @zhangf, Carolyn Bertozzi, and @fabian_theis, and supported by an amazing group of investors including @JorgeCondeBio @zakdoric Matt Kraning @ZettaVentures @dreidco @conviction @saranormous @svangel @valkyrie_vc and others. Biomni Lab is available for free today: biomni.phylo.bio Learn more in our launch post: phylo.bio/blog/company-f… We are also hosting launch events - join us at South San Francisco: luma.com/n8k8qb0n Virtual: luma.com/l5ryjaij We’re also hiring! phylo.bio/careers

This was a huge success. For the first time, we watched scientists and engineers iterate on a real challenge and present solutions in under 2 hours. It’s rare to see scientists at a hackathon, and this is clearly the beginning of something very special. An obvious missing piece here is real-world experimental validation, and this is exactly what we’re adding to the next event with @adaptyvbio. Stay tuned! Thank you to everyone who joined the first agentic bio hackathon - and to @TrueVentures for generously hosting, @RowanSci and @OpenRouter for co-sponsoring, and our fantastic judges @AriWagen, @geneticdrifts, @JaredXia , and Bennett.

@katyenko The first agentic bio hackathon ever!! Could hackathons be where future drug candidates will be found?!

Big thanks to @openrouter and @RowanSci for helping sponsor this event. Only a few slots left - sign up soon if you're interested! luma.com/0l5w97j0

@tomkrcha Congrats @tomkrcha !!! This is sick

Excited to launch Pencil INFINITE DESIGN CANVAS for Claude Code > Superfast WebGL canvas, fully editable, running parallel design agents > Runs locally with Claude Code → turn designs into code > Design files live in your git repo → Open json-based .pen format

@benjitaylor @seldom @alexvanderzon nice! when you're annotating, does it matter how precise your wording should be? and does this connect to any design-system or skills/principles? also floating bar so cool

@thejieg @seldom @alexvanderzon batched! whether you add 1 annotation or 100, when you click 'copy', you get the markdown output as one snippet containing all the feedback you provided

For all the Claude Code designers out there: We built Agentation to help you iterate faster. *Annotate anything* and get precise feedback to give to Claude. Give the docs a read: agentation.dev

made some edits to wdm? - new logo :') - persistent highlights: your saved explanations stay with the source link so that whenever you refer back to the source, all of your highlights are there waiting for you - new follow up questions: for big chunky topics that need additional follow up questions, there is now an added function for you to ask and read followup questions in context. just submitted to chrome web store, tysm all the fine folks on the waitlist for waiting! beta v soon <3 waitlist here: site-pi-sable.vercel.app

For the AI-curious scientists and bio-curious engineers: we’re hosting an agentic bio hackathon as a practical way to test AI tools on real scientific problems. Hosted by @trueventures and co-sponsored by @RowanSci. Come join us on Thursday, Jan. 29th luma.com/0l5w97j0

👋 Hi, I'm Felix and I work on Claude Cowork, bringing Claude Code closer to all kinds of knowledge work. It's an early and rough preview, please tag me in any feedback - we want to iterate very quickly and make it a little better every day.

@jgebbia Beautiful work Joe! And more importantly, factual information displayed with care

Announcing a profound partnership between National Design Studio and Sec Kennedy, Sec Rollins, CMS Administrator Oz, and FDA Commissioner Makary to bring the new Dietary Guidelines to life in the form of the New Pyramid. Shocking how misleading the one hanging in my second grade classroom was. Even more surprising would have been to tell my younger self one day I’d help redesign it. Eat whole foods, and enjoy realfood.gov @ndstudio @SecKennedy @SecRollins @DrOzCMS @DrMakaryFDA @PressSec @WhiteHouse @RapidResponse47

Wild that nowadays, you can turn your curiosities into tools in just a few hours time. Today, while reading, I found myself wishing for a lil tool that'd explain things to me in a lightweight but context-aware way without forcing me to leave the page. I then got v curious if I could make one with @cursor_ai. Turns out yes, very much yes. Built my first tool of 2026, affectionately (and temporarily named) wat dis mean? a chrome plugin that explains any highlighted text on web pages, pdf's and other text-based info. I can also catalog and save them in a library for me to refer back to later. a few flowy dreamy buildy hrs. 2026 is a wizarding year.

Payouts are live, which means you can now get rewarded for your scientific domain expertise. The reward is shown at the top right of every battle. Upon winning, USDC gets dropped directly into your account. Win battles - your gel is taking time to run anyway. 🧵

For those pushing science forward: today we’re launching the bioArena beta. bioarena.xyz