Bicentennial.VC

A Space Marine has 18 extra organs. 18 years from now, everyone can have these extra organs for the price of a laptop, small and specialized organs from our own tissue. @bitbio @UnitherPharma @LyGenesis_Inc @BiostageInc are already working on these extra organs. Make sure to check our website to understand exactly what will happen in the next 18 years. #Warhammer40k #spacemarine #longevity @bryan_johnson @davidasinclair @PeterAttiaMD

You don’t need to live 100 years. You need to live long enough to live forever. The bridge is being built THIS decade. Your only job is to still be here when it opens. LEV-2033.

Indeed. We now have 234 life-extension technologies listed on our website and have all ranked them by how many years they will likely add to the human lifespan. Which ones are your favorites David? You can pick your most favorite ones and share them with your fellow researchers.

@JoinLifespan What are more? I'll start: Social media Online dating Nuclear energy Smart phone AI companions Quantum computer Digital twin...

Once-laughable word pairings: Heart transplant Space travel Computer mouse In vitro fertilization Digital currency Search engine Gene editing Reusable rocket Artificial intelligence Personal genome Robo taxi Obesity cure Age reversal All sounded implausible. Until they weren’t

@JoinLifespan Indeed. We have 234 life-extension technologies listed on our website and have all ranked them by how many years they will add to the human lifespan. Which ones are your favorites? You can now pick your most favorite and share it with your fellow researchers.

we are within 5 years of the end of aging

The first glimpse of post cancer medicine Scientists are testing a personalized mRNA vaccine for pancreatic cancer, one of the deadliest cancers on Earth, and the early results are pretty amazing. Patients who responded to the vaccine didn’t just improve...many are still alive years later, up to ~6 years in some cases. Some of them remain cancer free, which is almost unheard of for pancreatic cancer. The vaccine is custom built for each patient, training the immune system to recognize and destroy their specific tumor. What makes this especially powerful: Pancreatic cancer usually comes back in over 80% of patients even after surgery. This approach may teach the immune system long term memory, preventing recurrence. Big picture: Personalized mRNA cancer vaccines can work. The immune system can be trained to suppress even aggressive cancers and the effects can last for years, not months.

This is the tweet you need to see.

@Dr_Singularity This is quite possible. We have listed all the 232 longevity startups building the future of anti-aging. Make your own lists and send them to your friends with the most potential lifespan extension technologies on our website. bicentennial.vc

All cancers will be curable by 2030s Immunotherapy is changing the game. Treatments that activate your immune system (like checkpoint inhibitors and CAR-T) are already producing long term remissions in cancers that used to be near certain death sentences. Early detection is getting radically better. Liquid biopsies (blood tests that detect cancer early) could catch tumors before they even form symptoms, which massively increases cure rates. AI + biology = acceleration AI is speeding up: drug discovery protein design treatment personalization Thanks to AI, we may reach 2100s level medicine in the 2030s. What many sci-fi authors predicted for 2100+, we could achieve far earlier. Progress is happening faster than even the most optimistic visionaries of the past expected. Plus insanely advanced nanotechnology and other technologies that we haven’t even invented yet. Make it to the mid 2030s and diseases will very likely stop being a real threat.

@Dr_Singularity This isn't even the most of it. We have listed all the 232 longevity startups building the future of anti-aging. Make your own lists and send them to your friends with the most potential lifespan extension technologies on our website. bicentennial.vc

We’re getting there (aging reversal). Breakthroughs like this are becoming more frequent each month, and more advanced each time. Scientists reverse brain aging, with a nasal spray. New therapy is turning back the clock in aging brains, healing inflammation, restoring memory and reshaping the future of brain age related therapies. Scientists at Texas A&M developed a nasal spray that may reverse brain aging by targeting chronic inflammation (“neuroinflammaging”), a key driver of memory decline. The spray delivers extracellular vesicles with microRNAs directly into the brain (via the nose), bypassing the blood brain barrier and reprogramming immune cells to reduce harmful inflammation. In aging mice, just two doses: reduced inflammation restored mitochondrial (energy) function improved memory and cognition within weeks, lasting months The treatment works by shutting down key inflammatory pathways (NLRP3, cGAS-STING) and reactivating the brain’s repair systems.

7 new cancer treatments currently in advanced clinical trials have hit the public just in April. It seems like cancer is becoming just like a bacterial infection, just take some anti-biotics and it'll be gone in a week. 1. Destroy cancer with sound 2. Destroy cancer with light 3. Destroy cancer with bacteria 4. Vaccinate against cancer by increasing PLD-1 levels 5. Vaccinate against cancer via a CD40 agonist 6. Destroy cancer via Microbiome Engineering with E.americana 7. Destroy cancer via Dandelion Root Extract There are 3 more cancer treatments and several microbiome engineering approaches you can all read up on our longevity index on our website for all cancer treatments currently in research. We have the most comprehensive and most up-to-date longevity index in the whole world.

🚨CANCER BREAKTHROUGH: Frog-Derived Gut Bacterium Completely ERADICATES 100% of Tumors After a SINGLE Dose in Mice A single IV dose of Ewingella americana achieved COMPLETE tumor elimination in 100% of treated mice—with NO detectable toxicity, outperforming BOTH chemo and immunotherapy. E. americana is a naturally occurring bacterium isolated from the gut microbiome of amphibians (tree frogs) and reptiles—NOT genetically engineered. In a colorectal cancer model, tumors weren’t just reduced—they were fully eliminated, with NO recurrence upon rechallenge, indicating durable immune protection. The new study found it rapidly targets tumors, multiplies inside the tumor microenvironment, and triggers a powerful immune response—activating T cells, B cells, and neutrophils for a dual attack. Investigators observed ~3,000-fold bacterial expansion within tumors within 24 hours, with NO detectable colonization in major organs. Despite IV delivery of live bacteria, there was NO significant toxicity, NO organ damage, and normal blood markers—while the bacteria cleared from circulation within 24 hours. The bacterium outperformed BOTH chemotherapy (doxorubicin, “red devil”) and immune checkpoint blockade (anti–PD-L1)—two pillars of modern cancer therapy. This represents one of the most striking preclinical cancer findings reported to date.

@scitechgirl Yes, two startups are already employing nanobots for their use, @NaNotics and @OisinBio with around $20M in funding each. Check them out on our Longevity Index on our website for more info.

🚨 Tiny “Nanobots” May Be Able to Clean Arteries From the Inside… Scientists are now exploring nanobots—microscopic machines that could one day target clogged arteries and break down fatty buildup from the inside. Instead of major heart procedures, future treatments may work at the cellular level, going straight to the blockage and helping restore blood flow in ways we’ve never seen before. It still sounds like science fiction… but early nanomedicine research is already showing how tiny particles can deliver treatment directly to problem areas with extreme precision. Could heart surgery one day be replaced by invisible machines working silently inside us? The future of medicine is getting smaller… and far more powerful. Source: Nature Nanotechnology. (n.d.). Nanomedicine and targeted drug delivery systems review. American Heart Association. (n.d.). Cardiovascular disease research updates.

🚨 Menopause Could Soon Be DELAYED… Science Just Changed Everything What if the body’s “biological clock” for menopause could be slowed down? Scientists are now studying ways to protect and repair the ovaries so they age more slowly. Early research suggests it may be possible to keep egg cells healthier for longer, which could delay menopause in the future. This could mean more than just fertility — it may also help protect heart, bone, and brain health linked to ovarian hormones. It’s still early research, but experts say we may be getting closer to something once thought impossible… slowing down one of the body’s natural timelines. The big question now is: how far can science go? Source National Institutes of Health. Repurposed drug may delay menopause, slow ovarian aging. NIH Record

Early Diagnostics have come incredibly far. 1. Full Body MRI 2. Galleri Test detecting 90% of cancers from a drop of blood 3. 200 Blood Markers and 15 more advanced diagnostics companies that you can find in the Longevity Index on our website consisting of 242 longevity companies. It's the most comprehensive and most up-to-date longevity index you can find. bicentennial.vc

I teach medical students that pancreatic cancer is a death sentence because we catch it too late. That may be about to change. NIH-funded researchers just developed a 4-marker blood test that detects pancreatic cancer with 91.9% accuracy across ALL stages -- and 87.5% for early-stage disease, when treatment actually works. The breakthrough: two newly discovered proteins (ANPEP and PIGR) combined with existing markers CA19-9 and THBS2. The old test alone caught only 76% of early cases. This panel catches nearly 88%. Why this matters: pancreatic cancer has a 5-year survival rate under 12%. The single biggest reason? By the time symptoms appear, it has already spread. A simple blood draw could change everything. As I wrote in "Lies I Taught in Medical School," we have spent decades treating late-stage disease instead of catching metabolic dysfunction early. This is what early detection actually looks like. Full breakdown coming on the Health Longevity Secrets podcast. Source: sciencedaily.com/releases/2026/… #PancreaticCancer #EarlyDetection #BloodTest #MetabolicHealth #CancerScreening

7 new cancer treatments currently in advanced clinical trials have hit the public just in April 1. Destroy cancer with sound 2. Destroy cancer with light 3. Destroy cancer with bacteria 4. Vaccinate against cancer by increasing PLD-1 levels 5. Vaccinate against cancer via a CD40 agonist 6. Destroy cancer via Microbiome Engineering with E.americana 7. Destroy cancer via Dandelion Root Extract There are 3 more cancer treatments and several microbiome engineering approaches you can all read up on our longevity index on our website for all cancer treatments currently in research. We have the most comprehensive and most up-to-date longevity index in the whole world.

Don't pull those yard weeds just yet. A common plant might be the next massive breakthrough in modern oncology. Canadian researchers have discovered that dandelion root extract can actively target and destroy up to 95% of cancer cells in just 48 hours. In laboratory studies, the extract acts like a precision biological tool, triggering programmed cell death in colon, pancreatic, and leukemia cells while leaving healthy, surrounding tissue completely untouched. By effectively shutting down tumor growth at the cellular level without the harsh side effects of traditional chemotherapy or radiation, this discovery is paving the way for upcoming human trials. It proves that some of our most powerful, side-effect-free medical solutions might just be growing right under our feet.

6 new cancer treatments have hit the public just in April 1. Destroy cancer with sound 2. Destroy cancer with light 3. Destroy cancer with bacteria 4. Vaccinate against cancer by increasing PLD-1 levels 5. Vaccinate against cancer via a CD40 agonist 6. Microbiome Engineering with E.americana There are 3 more cancer treatments and several microbiome engineering approaches you can all read up on our longevity index on our website for all cancer treatments currently in research. We have the most comprehensive and most up-to-date longevity index in the whole world.

🚨 This is INSANE. CANCER has been Cured via something found in Japanese forests. • Literally ERADICATED TUMORS IN A SINGLE DOSE • Head to Head against chemo & immuno — worked Way Better • No bad side effects • Prevented Recurrence: the cancer COULD NOT be brought back All this was possible via a single bacterium isolated from the intestines of Japanese tree frogs - Ewingella americana. 🐸 ➡️ When a single dose of the E. americana was injected into the veins of mice bearing colorectal cancer, the tumors were 100% Rapidly, Completely eliminated. ➡️ No side effects (except mild necessary inflammation, gone w/in 72 hrs). No signs of long-term toxicity (multi-month observation period). ➡️ It also induced immune memory against rechallenge (prevented cancer from coming back). ➡️ And importantly: Zero colonization in normal organs + GONE from the body w/in 24 hours. ➡️ It's Highly likely these results will translate well to humans & to other (especially solid tumor) cancer types. I pay attention to cancer studies (have for decades) and these are actually an INSANE results. ✅ Why E. americana is the perfect CANCER KILLING MACHINE: • E. americana thrives in the same (low oxygen, immunosuppressive) environment tumors thrive. And proteins + metabolic byproducts that cancer cells produce actually support the growth of E. americana, right there near the tumors. • Tumor blood vessels are poorly structured, very permeable/leaky. Because of this, E. americana can easily exit the bloodstream and enter the tumor tissue. IN OTHER WORDS: when this bacterium is injected, a perfect symphony transpires where it goes DIRECTLY to tumors & eliminates them  — while leaving normal cells & organs alone. 😯 ✅ HOW IT WORKS: E. americana eliminates cancer via 2 mechanisms: • Directly damages cancer cells. • Activates immune system — E. americana attracts T cells, B cells, and neutrophils to the tumor area (which then eliminate the cancer cells). ✅ WHY THIS IS LIKELY TO WORK IN HUMANS: Curing cancer via bacteria has been tried before. Here's what we know. ⚫️ Efficacy results shown in mice usually DO translate to humans— ie. bacteria that accumulate in mice tumors usually do the same w/in a human body ⚫️ Toxicity results shown in mice also show up similarly in humans ⚫️ There has Never been a mice study showing results this good OR w/o toxicity (the other ones showed a lot of toxicity & even death in the mice) ⚫️ In other bacteria cancer studies: the bacteria DID accumulate in normal organs. This one does not. ⚫️ IMPORTANTLY: all other bacteria that have been tried thus far were bioengineered/GMO. ⚫️ E. americana is naturally occurring & far less likely to lead to bad side effects. So anyway. Given these INSANENELY EFFECTIVE & safe results...they surely will FAST TRACK human trials on E. americana (perhaps on those who have nothing to lose and everything to gain) Right? ...Right?! I doubt it. It'll probably be forever... IF they even let this get to the public. They'll probably announce some new "miracle" genetic therapy instead, and try to pull all attention & resources toward that. UNLESS we do something. Be loud. Share this. Don't let this die down and be forgotten about. This is one of the most promising "1 & done" type of cancer solutions I've ever seen. But even if this does become mainstream, Natural Medicine & healthy living will still have it's place. This therapy does require an at least somewhat functioning immune system to work. And know: there are ways to fix your body.  Please see my other posts on cancer reversal via high dose IP6 (Inositol Hexaphosphate), large amounts of vegetable juicing (carrots/greens especially), high doses of specific mushrooms (Mesima, certain types of Reishi), etc.  I've posted tons of studies & reversal reports (often stage 4). Nature is amazing. Spread the word.

@RyanAFournier Just a marketing stunt. You'll be able to copy your brain in 10 years from now without any invasive procedures.

Sam Altman has admitted he is on a waitlist for a procedure that would digitize his brain. The procedure would kill him. He considers this an acceptable trade for digital immortality. This is the person making decisions about the future of artificial intelligence for hundreds of millions of users. A man who views ending his own biological life as a reasonable step toward uploading his consciousness to the cloud. These are not the priorities of a stable leader.

@Balboa17761 @FluentInFinance All of them, because manufacturers will make a lot of money from them. Bacterial and sound treatments are also very cheap to manufacture, so cheap competition is likely to reduce prices.

@bicentennialvc @FluentInFinance How many of these are or will be available to the public?

JUST IN: Scientists built bacteria that EATS cancer from the inside out. The future of cancer treatment isn't a drug. It's a living organism that devours tumors from the inside. Here's how it works: Solid tumors have a dead center. No oxygen. No blood flow. Just dead cells and nutrients sitting there. Most cancer drugs can't survive in that environment. They get blocked. They break down. They never reach the core where the tumor is most protected. But researchers at the University of Waterloo found something that THRIVES there. It's called Clostridium sporogenes. A bacteria found in soil that loves oxygen-free environments. Researchers send spores directly into the tumor: 1. The bacteria wakes up in the dead, oxygen-free center 2. It starts consuming nutrients and growing 3. It multiplies and COLONIZES the space 4. It eats the tumor from the inside out Then they added something called quorum sensing. Bacteria communicate through chemical signals. When enough bacteria pile up INSIDE the tumor, those signals flip on the oxygen-tolerance gene. This means the bacteria won't activate in your bloodstream. It only activates inside the tumor, where it belongs. Think about what that means. Chemo hits everything. Good cells. Bad cells. Your hair. Your gut. Your immune system. The cancer suffers, but so does the rest of your body. This is different. This is a PRECISION weapon. A living, self-regulating machine that targets only the tumor's environment and ignores healthy tissue. The team is now heading into preclinical trials and testing it on real tumors. We are watching history happen.

49 patients with rectal cancer. All received an immunotherapy drug called dostarlimab for 6 months before scheduled surgery. 100% had complete tumor clearance. Every single one. None of them needed surgery. None needed chemo. None needed radiation. 96% are still cancer-free at 2 years. Published in the New England Journal of Medicine. Phase 2 trial at Memorial Sloan Kettering, led by Andrea Cercek. When the same drug was tested in 54 patients with other dMMR cancers (stomach, liver, bladder, gynecologic), 65% also achieved complete response. 82 of 84 responders kept their organs. The key: all these cancers share a genetic feature called mismatch repair deficiency (dMMR). About 15% of all solid tumors carry it. Their DNA repair is broken, which makes them unusually visible to the immune system when you remove the brakes. Dostarlimab removes the brakes. The immune system does the rest. For this subset of patients, the most effective cancer treatment may be no surgery at all. Just six months of immunotherapy, then watch and wait.

In 2011, a neuroscientist at MIT named Dr. Li-Huei Tsai made a discovery that should have been on the front page of every newspaper on Earth. She exposed mice with advanced Alzheimer's disease to a flickering light pulsing at exactly 40 Hz — forty flashes per second. Nothing else. No drugs. No surgery. Just light at a specific frequency. Within one hour, the amyloid-beta plaques in their brains — the protein deposits that define Alzheimer's — began to dissolve. Not slow. Not gradually. Within sixty minutes. After seven days of daily 40 Hz exposure, plaque levels dropped by 50%. The mice regained memory function. Their neurons began firing in synchrony again. The brain's immune cells — microglia — activated and started clearing the toxic buildup like a cleaning crew that had been asleep for years. The study was published in Nature. The most prestigious scientific journal on the planet. Peer-reviewed. Replicated. Confirmed. That was 2016. It is now 2026. 40 million people worldwide have Alzheimer's. The pharmaceutical industry generates $13 billion per year from Alzheimer's drugs that do not reverse the disease. Not one of them. They slow it. Maybe. Temporarily. At $26,000 per year per patient. A 40 Hz light costs less than a dollar to produce. Dr. Tsai is still at MIT. Her research continues. Phase III human trials are underway. But you will not see this on the evening news. You will not hear your doctor mention it. You will not find it in any pharmacy. Because a frequency that costs nothing cannot sustain a $13 billion industry. The light is 40 Hz. The frequency is real. The science is published. And 40 million people are still waiting for permission to use it.