Matt Cohen

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Matt Cohen

Matt Cohen

@mattybcohen

🌊 Founder & Managing Partner @ripple_ventures 🎙 Host of @TankTalkPodcast / Family Office - https://t.co/DTLouaREEX - Be an LP https://t.co/bxNoxlLOEy

Toronto, Ontario Katılım Mayıs 2012
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Matt Cohen
Matt Cohen@mattybcohen·
Thanks for inviting me onto the @BNNBloomberg show today @JonErlichman to discuss everything happening in the venture capital markets these days and how Canada and our entrepreneurs are playing a vital role in creating the next great tech leaders!
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Matt Cohen
Matt Cohen@mattybcohen·
@JasonrShuman drove Uber at night to fund himself while sourcing VC deals by day. One of those deals was @latchaccess Now he's a GP at @PrimaryVC , which scaled from $190M to $1.6B AUM without ever drifting from seed. In Episode 320 of Tank Talks, we get into: → Why most VC platform teams are built to fail, and how Primary's 60-person Impact team delivers customers and talent, not just capital → Why software-only moats are dead, and why he's betting on hardware-activated agent networks → Primary's incubation model: backing founders only after the wedge is validated → The lessons from winding down his footwear brand Category5, and how that founder's scar tissue shapes how he invests The throughline for any emerging manager: Differentiation isn't a tagline. It's an operating model you build deliberately and refuse to dilute as you scale. #venturecapital #seedinvesting
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Jonny
Jonny@hsu_jonny·
I'm super excited to announce our $7.2M seed round + a strategic collaboration with @PacBio! Together, we'll be generating long-read, bulk-RNA sequencing directly from patient tumours spanning multiple cancer indications. This is extremely rich data that will be used to further train and evaluate our models. @blankbio_, we are focused on training RNA foundation models that can learn and predict disease progression and treatment response in patients. These are the biological insights that will enable us to design smaller, more efficient clinical trials with higher success rates. Huge thank you to all of our investors who have been amazing supporters from the beginning. For more details, please check out the links below. Press release: blank.bio/seed-announcem… Blog from the team: blank.bio/accelerate-cli… We're hiring: ycombinator.com/companies/blan…
Blank Bio@blankbio_

Today, we’re excited to announce our $7.2M seed round alongside a strategic collaboration with @PacBio! At Blank Bio, we help pharma make more informed decisions in clinical trials by capturing the biology that makes each patient’s tumour unique. We do this by training RNA foundation models to learn the patterns that shape disease progression and how patients respond to treatment. In our collaboration with @PacBio, we will generate long-read, bulk RNA-sequencing data from patient tumour samples across multiple indications. This dataset will be used to further train and evaluate our models. Our models are currently focused on two main applications. First, we predict how a patient’s disease is likely to progress over time from their molecular profile. Through the FDA-recommended approach of covariate adjustment, these RNA prognostic scores can help clinical development teams design trials that reach statistical power with fewer patients. Second, we’re working to help pharma teams understand biological differences between patients so they can identify who is most likely to respond to a given therapy. We are thankful to @definevc, @LeonisCapital, Nova Threshold, @ripple_ventures, @SignalFire, @ycombinator, and other investors for being early supporters in our vision. This financing will support the continued development of our foundation models, expanded collaborations with pharma, and growing our patient-level datasets. Read the press release: blank.bio/seed-announcem… Read the blog from the team: blank.bio/accelerate-cli… Learn more about Blank Bio: blank.bio

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Matt Cohen retweetledi
Blank Bio
Blank Bio@blankbio_·
Today, we’re excited to announce our $7.2M seed round alongside a strategic collaboration with @PacBio! At Blank Bio, we help pharma make more informed decisions in clinical trials by capturing the biology that makes each patient’s tumour unique. We do this by training RNA foundation models to learn the patterns that shape disease progression and how patients respond to treatment. In our collaboration with @PacBio, we will generate long-read, bulk RNA-sequencing data from patient tumour samples across multiple indications. This dataset will be used to further train and evaluate our models. Our models are currently focused on two main applications. First, we predict how a patient’s disease is likely to progress over time from their molecular profile. Through the FDA-recommended approach of covariate adjustment, these RNA prognostic scores can help clinical development teams design trials that reach statistical power with fewer patients. Second, we’re working to help pharma teams understand biological differences between patients so they can identify who is most likely to respond to a given therapy. We are thankful to @definevc, @LeonisCapital, Nova Threshold, @ripple_ventures, @SignalFire, @ycombinator, and other investors for being early supporters in our vision. This financing will support the continued development of our foundation models, expanded collaborations with pharma, and growing our patient-level datasets. Read the press release: blank.bio/seed-announcem… Read the blog from the team: blank.bio/accelerate-cli… Learn more about Blank Bio: blank.bio
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Matt Cohen
Matt Cohen@mattybcohen·
🇨🇦 Bring it home 🇨🇦 New Tank Talks with @JonLoveKingSett, founder of @kingsettcapital , one of Canada's largest private equity real estate platforms. His thesis: Canada doesn't have a capital problem. It has a permission problem. 👇We dug into: The $25B Canada Strong sovereign wealth fund Tim Hodgson's Major Projects Office and the 5-10 shovel-ready projects promised by spring 2027 Why institutional capital is finally coming home to Canada And on real estate: Triple-A office is quietly the strongest asset class in the country For-sale residential is in pain, but a sharp recovery is coming Office-to-hotel conversions are just getting started The capital is here. The talent is here. The opportunities are here. What's missing is permission to build. Worth your time if you care about where Canada actually goes from here. (Links Below)
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Matt Cohen
Matt Cohen@mattybcohen·
New site, new era at @ripple_ventures This past quarter we backed founders across AI infra, AI for science, deep tech, and AI-native services. Full write-up + fresh look: rippleventures.com
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Matt Cohen
Matt Cohen@mattybcohen·
Big day for our portco @urunml - officially out of stealth. The bottleneck in generative AI has moved from intelligence per token to tokens per second. uRun is building the inference cloud for the interactive era — video, avatars, and world models that hold session state and stay alive between turns. The team has done this before: @keeganmccallum3 scaled video inference to a million users in 4 days at Luma, Sean Kane co-authored Docker: Up & Running and built New Relic's container platform, and @mattkrzus spent years at AWS compiling models for Just Walk Out and Panorama. If you're a research team, game studio, or product team building real-time generative experiences, join the waitlist. Proud to be early.
Keegan McCallum@keeganmccallum3

Today, we come out of stealth. 👋 @urunml is the inference cloud for the interactive era. We wrote down why we're building it and what we believe. Manifesto→ blog.urun.sh Join the waitlist → urun.sh

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Matt Cohen
Matt Cohen@mattybcohen·
New @TankTalkPodcast with @ruffoloj. One of the busiest weeks Canadian tech has had in a while 👇 We get into: - Canada's proposed AI chatbot ban for under-16s - Exit tax on Canadians leaving for the U.S. - @cohere's rumoured merger with a German AI player - @invoker back as interim CEO at @hootsuite Policy, sovereign AI, talent flight, and a founder comeback. The real question is bigger than any one story: what kind of innovation economy does Canada actually want to be? Full episode below
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Matt Cohen
Matt Cohen@mattybcohen·
Ask ten founders to explain venture debt and you'll get ten different answers. Most of them wrong. New Tank Talks: @marshallhawks spent 16 years at SVB structuring deals for Airbnb, Twitch, and Fitbit. Then watched the third-largest bank failure in US history from the inside. We unpacked what founders actually get wrong about venture debt in 2026, from confusing venture banking with private credit, to obsessing over terms when the lending partner matters more. The market hit $62B in volume with more players than ever. Worth your time if you're thinking about your capital stack. 🎙️ Link below
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Matt Cohen
Matt Cohen@mattybcohen·
We led Hyper's pre-seed round. Today @MotorolaUS Solutions acquired them. AI voice agents that handle non-emergency 911 calls so human operators can focus on real emergencies. From idea to live across North America, resolving 75% of non-emergency volume autonomously. 22 months. Pre-seed to strategic acquisition. Congrats @8ENs @DamianMcCabe and the whole @call_hyper team. 🇨🇦
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